Genome Instability Induced by Low Levels of Replicative DNA Polymerases in Yeast

How cells ensure correct repair of DNA double-strand breaks

(2018) Joonyoung Her et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GC content elevates mutation and recombination rates in the yeastSaccharomyces cerevisiae

(2018) Denis A. Kiktev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Properties of Mitotic and Meiotic Recombination in the Tandemly-RepeatedCUP1Gene Cluster in the YeastSaccharomyces cerevisiae

(2017) Ying Zhao et al.   GENETICS

SIR2suppresses replication gaps and genome instability by balancing replication between repetitive and unique sequences

(2017) Eric J. Foss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA replication stress restricts ribosomal DNA copy number

(2017) Devika Salim et al.   PLoS Genetics

Properties of Mitotic and Meiotic Recombination in the Tandemly-RepeatedCUP1Gene Cluster in the YeastSaccharomyces cerevisiae

(2017) Ying Zhao et al.   GENETICS

DNA replication stress: from molecular mechanisms to human disease

(2016) Sergio Muñoz et al.   CHROMOSOMA

DNA replication stress and cancer: cause or cure?

(2016) Elaine M Taylor et al.   Future Oncology

Global analysis of genomic instability caused by DNA replication stress inSaccharomyces cerevisiae

(2016) Dao-Qiong Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Polymerases Divide the Labor of Genome Replication

(2016) Scott A. Lujan et al.   TRENDS IN CELL BIOLOGY

DNA Replication Stress as a Hallmark of Cancer

(2015) Morgane Macheret et al.   Annual Review of Pathology-Mechanisms of Disease

Eukaryotic DNA polymerase ζ

(2015) Alena V. Makarova et al.   DNA REPAIR

Elevated Genome-Wide Instability in Yeast Mutants Lacking RNase H Activity

(2015) K. O'Connell et al.   GENETICS

Genome-wide analyses of LINE–LINE-mediated nonallelic homologous recombination

(2015) Michał Startek et al.   NUCLEIC ACIDS RESEARCH

Extrachromosomal circular DNA is common in yeast

(2015) Henrik D. Møller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Destabilizing Effects Associated with Top1 Loss or Accumulation of Top1 Cleavage Complexes in Yeast

(2015) Sabrina L. Andersen et al.   PLoS Genetics

DNA replication stress: Causes, resolution and disease

(2014) Abdelghani Mazouzi et al.   EXPERIMENTAL CELL RESEARCH

High-Resolution Mapping of Two Types of Spontaneous Mitotic Gene Conversion Events in Saccharomyces cerevisiae

(2014) Eunice Yim et al.   GENETICS

Mechanisms and Regulation of Mitotic Recombination in Saccharomyces cerevisiae

(2014) L. S. Symington et al.   GENETICS

Correlation between frequency of non-allelic homologous recombination and homology properties: evidence from homology-mediated CNV mutations in the human genome

(2014) Zhen Peng et al.   HUMAN MOLECULAR GENETICS

Genome-wide high-resolution mapping of chromosome fragile sites in Saccharomyces cerevisiae

(2014) W. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Precise estimates of mutation rate and spectrum in yeast

(2014) Y. O. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of Naturally Evolved CUP1 Tandem Arrays in Yeast Indicate That These Arrays Are Generated by Unequal Nonhomologous Recombination

(2014) Ying Zhao et al.   G3-Genes Genomes Genetics

Gene Copy-Number Variation in Haploid and Diploid Strains of the Yeast Saccharomyces cerevisiae

(2013) H. Zhang et al.   GENETICS

Germline and somatic polymerase ϵ and δ mutations define a new class of hypermutated colorectal and endometrial cancers

(2013) Sarah Briggs et al.   JOURNAL OF PATHOLOGY

High-Resolution Mapping of Spontaneous Mitotic Recombination Hotspots on the 1.1 Mb Arm of Yeast Chromosome IV

(2013) Jordan St. Charles et al.   PLoS Genetics

Fragile Site Instability in Saccharomyces cerevisiae Causes Loss of Heterozygosity by Mitotic Crossovers and Break-Induced Replication

(2013) Danielle M. Rosen et al.   PLoS Genetics

A Natural Polymorphism in rDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan

(2013) Elizabeth X. Kwan et al.   PLoS Genetics

High-Resolution Genome-Wide Analysis of Irradiated (UV and  -Rays) Diploid Yeast Cells Reveals a High Frequency of Genomic Loss of Heterozygosity (LOH) Events

(2012) J. St. Charles et al.   GENETICS

Reciprocal uniparental disomy in yeast

(2012) S. L. Andersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Double-Strand Break End Resection and Repair Pathway Choice

(2011) Lorraine S. Symington et al.   Annual Review of Genetics

Friedreich's Ataxia (GAA)n•(TTC)n Repeats Strongly Stimulate Mitotic Crossovers in Saccharomyces cerevisae

(2011) Wei Tang et al.   PLoS Genetics

Systematic identification of fragile sites via genome-wide location analysis of γ-H2AX

(2010) Rachel K Szilard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Optimized detection of sequence variation in heterozygous genomes using DNA microarrays with isothermal-melting probes

(2010) D. Gresham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms

(2010) J. L. McCulley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Baker's Yeast Diploid Genome Is Remarkably Stable in Vegetative Growth and Meiosis

(2010) K. T. Nishant et al.   PLoS Genetics

Participation of DNA Polymerase   in Replication of Undamaged DNA in Saccharomyces cerevisiae

(2009) M. R. Northam et al.   GENETICS

Chromosome Aberrations Resulting From Double-Strand DNA Breaks at a Naturally Occurring Yeast Fragile Site Composed of Inverted Ty Elements Are Independent of Mre11p and Sae2p

(2009) A. M. Casper et al.   GENETICS

Highly Transcribed RNA Polymerase II Genes Are Impediments to Replication Fork Progression in Saccharomyces cerevisiae

(2009) Anna Azvolinsky et al.   MOLECULAR CELL

A Fine-Structure Map of Spontaneous Mitotic Crossovers in the Yeast Saccharomyces cerevisiae

(2009) Phoebe S. Lee et al.   PLoS Genetics

Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair

(2008) Hyun-Min Kim et al.   EMBO JOURNAL

Reduced Levels of DNA Polymerase   Induce Chromosome Fragile Site Instability in Yeast

(2008) F. J. Lemoine et al.   MOLECULAR AND CELLULAR BIOLOGY

High-resolution mapping of meiotic crossovers and non-crossovers in yeast

(2008) Eugenio Mancera et al.   NATURE

Low Levels of DNA Polymerase Alpha Induce Mitotic and Meiotic Instability in the Ribosomal DNA Gene Cluster of Saccharomyces cerevisiae

(2008) Anne M. Casper et al.   PLoS Genetics

Hypermutability of Damaged Single-Strand DNA Formed at Double-Strand Breaks and Uncapped Telomeres in Yeast Saccharomyces cerevisiae

(2008) Yong Yang et al.   PLoS Genetics