Fragile Site Instability in Saccharomyces cerevisiae Causes Loss of Heterozygosity by Mitotic Crossovers and Break-Induced Replication

High-Resolution Mapping of Spontaneous Mitotic Recombination Hotspots on the 1.1 Mb Arm of Yeast Chromosome IV

(2013) Jordan St. Charles et al.   PLoS Genetics

Histone H3K56 Acetylation, Rad52, and Non-DNA Repair Factors Control Double-Strand Break Repair Choice with the Sister Chromatid

(2013) Sandra Muñoz-Galván et al.   PLoS Genetics

High-Resolution Genome-Wide Analysis of Irradiated (UV and  -Rays) Diploid Yeast Cells Reveals a High Frequency of Genomic Loss of Heterozygosity (LOH) Events

(2012) J. St. Charles et al.   GENETICS

The complex basis underlying common fragile site instability in cancer

(2012) Efrat Ozeri-Galai et al.   TRENDS IN GENETICS

Rapid Analysis of Saccharomyces cerevisiae Genome Rearrangements by Multiplex Ligation–Dependent Probe Amplification

(2012) Jason E. Chan et al.   PLoS Genetics

Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development

(2011) Assaf C. Bester et al.   CELL

Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes

(2011) Anne Helmrich et al.   MOLECULAR CELL

Failure of Origin Activation in Response to Fork Stalling Leads to Chromosomal Instability at Fragile Sites

(2011) Efrat Ozeri-Galai et al.   MOLECULAR CELL

A continuum model for tumour suppression

(2011) Alice H. Berger et al.   NATURE

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

(2011) Anne Letessier et al.   NATURE

Friedreich's Ataxia (GAA)n•(TTC)n Repeats Strongly Stimulate Mitotic Crossovers in Saccharomyces cerevisae

(2011) Wei Tang et al.   PLoS Genetics

Meiotic Recombination Intermediates Are Resolved with Minimal Crossover Formation during Return-to-Growth, an Analogue of the Mitotic Cell Cycle

(2011) Yaron Dayani et al.   PLoS Genetics

A Genetic and Structural Study of Genome Rearrangements Mediated by High Copy Repeat Ty1 Elements

(2011) Jason E. Chan et al.   PLoS Genetics

Meiotic versus mitotic recombination: Two different routes for double-strand break repair

(2010) Sabrina L. Andersen et al.   BIOESSAYS

Break-induced replication: What is it and what is it for?

(2010) Bertrand Llorente et al.   CELL CYCLE

Replication dynamics at common fragile site FRA6E

(2010) Elisa Palumbo et al.   CHROMOSOMA

Deletion at Fragile Sites Is a Common and Early Event in Barrett's Esophagus

(2010) L. A. Lai et al.   MOLECULAR CANCER RESEARCH

Mus81 and Yen1 Promote Reciprocal Exchange during Mitotic Recombination to Maintain Genome Integrity in Budding Yeast

(2010) Chu Kwen Ho et al.   MOLECULAR CELL

Molecular Structures of Crossover and Noncrossover Intermediates during Gap Repair in Yeast: Implications for Recombination

(2010) Katrina Mitchel et al.   MOLECULAR CELL

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

Double Holliday junctions are intermediates of DNA break repair

(2010) Malgorzata Bzymek et al.   NATURE

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitotic gene conversion events induced in G1-synchronized yeast cells by gamma rays are similar to spontaneous conversion events

(2010) P. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defective Resection at DNA Double-Strand Breaks Leads to De Novo Telomere Formation and Enhances Gene Targeting

(2010) Woo-Hyun Chung et al.   PLoS Genetics

Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites

(2009) Allison A Burrow et al.   BMC GENOMICS

Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast

(2009) A. L. Paek et al.   GENES & DEVELOPMENT

Chromosome Aberrations Resulting From Double-Strand DNA Breaks at a Naturally Occurring Yeast Fragile Site Composed of Inverted Ty Elements Are Independent of Mre11p and Sae2p

(2009) A. M. Casper et al.   GENETICS

A Fine-Structure Map of Spontaneous Mitotic Crossovers in the Yeast Saccharomyces cerevisiae

(2009) Phoebe S. Lee et al.   PLoS Genetics

Reduced Levels of DNA Polymerase   Induce Chromosome Fragile Site Instability in Yeast

(2008) F. J. Lemoine et al.   MOLECULAR AND CELLULAR BIOLOGY

High-resolution mapping of meiotic crossovers and non-crossovers in yeast

(2008) Eugenio Mancera et al.   NATURE

Genome instability: a mechanistic view of its causes and consequences

(2008) Andrés Aguilera et al.   NATURE REVIEWS GENETICS

Low Levels of DNA Polymerase Alpha Induce Mitotic and Meiotic Instability in the Ribosomal DNA Gene Cluster of Saccharomyces cerevisiae

(2008) Anne M. Casper et al.   PLoS Genetics