Tim3 binding to galectin-9 stimulates antimicrobial immunity

Lack of TIM-3 Immunoregulation in Multiple Sclerosis

(2014) L. Yang et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis-Specific CD8+ T Cells Require Perforin to Kill Target Cells and Provide Protection In Vivo

(2014) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Caspase-1 Independent IL-1  Production Is Critical for Host Resistance to Mycobacterium tuberculosis and Does Not Require TLR Signaling In Vivo

(2010) K. D. Mayer-Barber et al.   JOURNAL OF IMMUNOLOGY

Interleukin-1  (IL-1 ) Processing Pathway

(2010) A. Weber et al.   Science Signaling

IL-1β Stimulates the Expression of Prostaglandin Receptor EP4 in Human Chondrocytes by Increasing Production of Prostaglandin E2

(2009) Yusuke Watanabe et al.   CONNECTIVE TISSUE RESEARCH

Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

(2009) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

(2009) Maziar Divangahi et al.   NATURE IMMUNOLOGY

The Caspase-1 Inflammasome: A Pilot of Innate Immune Responses

(2008) Hong Bing Yu et al.   Cell Host & Microbe

Mycobacterium tuberculosis Prevents Inflammasome Activation

(2008) Sharon S. Master et al.   Cell Host & Microbe

ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection

(2008) Ingrid C. Koo et al.   CELLULAR MICROBIOLOGY

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor Necrosis Factor Blockers Influence Macrophage Responses toMycobacterium tuberculosis

(2008) James Harris et al.   JOURNAL OF INFECTIOUS DISEASES

Innate Invariant NKT Cells Recognize Mycobacterium tuberculosis–Infected Macrophages, Produce Interferon-γ, and Kill Intracellular Bacteria

(2008) Isabel Sada-Ovalle et al.   PLoS Pathogens