Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity

Plasma-derived extracellular vesicle proteins as a source of biomarkers for lung adenocarcinoma

(2017) Jody Vykoukal et al.   Oncotarget

The Emerging Role of B Cells in Tumor Immunity

(2016) Peiling Tsou et al.   CANCER RESEARCH

Circulating autoantibodies in cancer patients have high specificity for glycoxidation modified histone H2A

(2016) Abdul Rouf Mir et al.   CLINICA CHIMICA ACTA

B Cells Promote Pancreatic Tumorigenesis

(2016) A. Roghanian et al.   Cancer Discovery

A systematic review of serum autoantibodies as biomarkers for pancreatic cancer detection

(2016) Karin Dumstrei et al.   Oncotarget

An Autoimmune Response Signature Associated with the Development of Triple-Negative Breast Cancer Reflects Disease Pathogenesis

(2015) H. Katayama et al.   CANCER RESEARCH

Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma

(2015) Michela Capello et al.   JNCI-Journal of the National Cancer Institute

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

(2015) Shabnam Shalapour et al.   NATURE

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

(2015) Lin Zhang et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma

(2015) Michela Capello et al.   JNCI-Journal of the National Cancer Institute

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

Boosting the MHC Class II-Restricted Tumor Antigen Presentation to CD4+ T Helper Cells: A Critical Issue for Triggering Protective Immunity and Re-Orienting the Tumor Microenvironment Toward an Anti-Tumor State

(2014) Roberto S. Accolla et al.   Frontiers in Oncology

Serologic Autoantibodies as Diagnostic Cancer Biomarkers--A Review

(2013) P. Zaenker et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Autoantibodies to Ezrin are an early sign of pancreatic cancer in humans and in genetically engineered mouse models

(2013) Michela Capello et al.   Journal of Hematology & Oncology

Dendritic Cell-Derived Exosomes Need To Activate Both T and B Cells To Induce Antitumor Immunity

(2013) T. I. Naslund et al.   JOURNAL OF IMMUNOLOGY

Cancer immunotherapy with exosomes requires B-cell activation

(2013) Tanja I Näslund et al.   OncoImmunology

Autoantibody Signatures Involving Glycolysis and Splicesome Proteins Precede a Diagnosis of Breast Cancer among Postmenopausal Women

(2012) J. J. Ladd et al.   CANCER RESEARCH

The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes

(2012) Nathalie Cloutier et al.   EMBO Molecular Medicine

Exosome removal as a therapeutic adjuvant in cancer

(2012) Annette M Marleau et al.   Journal of Translational Medicine

Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC

(2011) Christina Battke et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

α-enolase: a promising therapeutic and diagnostic tumor target

(2011) Michela Capello et al.   FEBS Journal

Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy

(2011) Valentina Ciravolo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Antigen Localization Controls T Cell-Mediated Tumor Immunity

(2011) I. S. Zeelenberg et al.   JOURNAL OF IMMUNOLOGY

Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3

(2011) T. Aung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of Smoothened Activates the Sonic Hedgehog Signaling Pathway in Pancreatic Cancer-Associated Fibroblasts

(2010) K. Walter et al.   CLINICAL CANCER RESEARCH

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)

(2010) Marta Szajnik et al.   PLoS One

Antigen-loaded exosomes alone induce Th1-type memory through a B cell-dependent mechanism

(2009) K. R. Qazi et al.   BLOOD

Serum autoantibodies as biomarkers for early cancer detection

(2009) Hwee Tong Tan et al.   FEBS Journal

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE