Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy

Microvesicles: Messengers and mediators of tumor progression

(2011) Khalid Al-Nedawi et al.   CELL CYCLE

Anti-HER2 neoadjuvant and adjuvant therapies in HER2 positive breast cancer

(2010) V. Guarneri et al.   CANCER TREATMENT REVIEWS

HER2 as a target for breast cancer therapy

(2010) Elda Tagliabue et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Lapatinib and breast cancer: current indications and outlook for the future

(2010) Cynthia Moreira et al.   Expert Review of Anticancer Therapy

Shed HER2 extracellular domain in HER2-mediated tumor growth and in trastuzumab susceptibility

(2010) Gaia C. Ghedini et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Randomized Study of Lapatinib Alone or in Combination With Trastuzumab in Women With ErbB2-Positive, Trastuzumab-Refractory Metastatic Breast Cancer

(2010) Kimberly L. Blackwell et al.   JOURNAL OF CLINICAL ONCOLOGY

Management of breast cancer with targeted agents: importance of heterogenicity

(2010) Serena Di Cosimo et al.   Nature Reviews Clinical Oncology

Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)

(2010) Marta Szajnik et al.   PLoS One

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

(2009) Britta Weigelt et al.   BREAST CANCER RESEARCH AND TREATMENT

Utility of Serum HER2 Extracellular Domain Assessment in Clinical Decision Making: Pooled Analysis of Four Trials of Trastuzumab in Metastatic Breast Cancer

(2009) Siân Lennon et al.   JOURNAL OF CLINICAL ONCOLOGY

A Naturally Occurring HER2 Carboxy-Terminal Fragment Promotes Mammary Tumor Growth and Metastasis

(2009) K. Pedersen et al.   MOLECULAR AND CELLULAR BIOLOGY

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

Vaccination with autologous tumor-loaded dendritic cells induces clinical and immunologic responses in indolent B-cell lymphoma patients with relapsed and measurable disease: a pilot study

(2008) M. Di Nicola et al.   BLOOD

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Generation of novel, secreted epidermal growth factor receptor (EGFR/ErbB1) isoforms via metalloprotease-dependent ectodomain shedding and exosome secretion

(2007) Michael P. Sanderson et al.   JOURNAL OF CELLULAR BIOCHEMISTRY