Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-10-16
DOI
10.1038/s41467-018-06686-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial
- (2018) Zhi-Wei Lai et al. LANCET
- Single cell analysis of kynurenine and System L amino acid transport in T cells
- (2018) Linda V. Sinclair et al. Nature Communications
- Blockade of Treg Cell Differentiation and Function by the Interleukin-21-Mechanistic Target of Rapamycin Axis Via Suppression of Autophagy in Patients With Systemic Lupus Erythematosus
- (2018) Hiroshi Kato et al. Arthritis & Rheumatology
- Follicular Helper T Cells in Systemic Lupus Erythematosus
- (2018) Sun Jung Kim et al. Frontiers in Immunology
- Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
- (2017) Jonatan Ersching et al. IMMUNITY
- T follicular regulatory cells in mice and men
- (2017) Ana Raquel Maceiras et al. IMMUNOLOGY
- Mammalian target of rapamycin complex 1 signalling is essential for germinal centre reaction
- (2017) Bingshou Li et al. IMMUNOLOGY
- B cell–derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity
- (2017) Tanvi Arkatkar et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+Th Cells
- (2017) Kaitlin A. Read et al. JOURNAL OF IMMUNOLOGY
- Immunometabolism in systemic lupus erythematosus
- (2017) Laurence Morel Nature Reviews Rheumatology
- Review: Metabolic Control of Immune System Activation in Rheumatic Diseases
- (2017) Andras Perl Arthritis & Rheumatology
- T follicular helper cells in human autoimmunity
- (2016) Hideki Ueno CURRENT OPINION IN IMMUNOLOGY
- T follicular helper (Tfh) cells in lupus: Activation and involvement in SLE pathogenesis
- (2016) Patrick Blanco et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation
- (2016) Hu Zeng et al. IMMUNITY
- mTOR has distinct functions in generating versus sustaining humoral immunity
- (2016) Derek D. Jones et al. JOURNAL OF CLINICAL INVESTIGATION
- Tissue-specific programming of memory CD8 T cell subsets impacts protection against lethal respiratory virus infection
- (2016) Georges Abboud et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity
- (2016) Phillip P. Domeier et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses
- (2016) Jialong Yang et al. eLife
- Follicular Helper T Cells in Systemic Lupus Erythematosus: Why Should They Be Considered as Interesting Therapeutic Targets?
- (2016) Matthieu Sawaf et al. Journal of Immunology Research
- The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells
- (2015) John P. Ray et al. IMMUNITY
- An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells
- (2015) Hao Wu et al. JOURNAL OF IMMUNOLOGY
- Glucose Oxidation Is Critical for CD4+T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus
- (2015) Yiming Yin et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Circulating Plasmablasts Induce the Differentiation of Human T Follicular Helper Cells via IL-6 Production
- (2015) Konstantia-Maria Chavele et al. JOURNAL OF IMMUNOLOGY
- Natural Killer Cells and Innate Interferon Gamma Participate in the Host Defense against Respiratory Vaccinia Virus Infection
- (2015) Georges Abboud et al. JOURNAL OF VIROLOGY
- T cells as a therapeutic target in SLE
- (2015) D Comte et al. LUPUS
- Regulation of T cells by mTOR: the known knowns and the known unknowns
- (2015) Kristen N. Pollizzi et al. TRENDS IN IMMUNOLOGY
- Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus
- (2015) Tue Kruse Rasmussen et al. ARTHRITIS RESEARCH & THERAPY
- PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
- (2015) Nikolaos Patsoukis et al. Nature Communications
- Preventing Allograft Rejection by Targeting Immune Metabolism
- (2015) Chen-Fang Lee et al. Cell Reports
- Interleukin-21 Receptor Blockade Inhibits Secondary Humoral Responses and Halts the Progression of Preestablished Disease in the (NZB × NZW)F1 Systemic Lupus Erythematosus Model
- (2015) Ming Zhang et al. Arthritis & Rheumatology
- Transcription Factor STAT3 and Type I Interferons Are Corepressive Insulators for Differentiation of Follicular Helper and T Helper 1 Cells
- (2014) John P. Ray et al. IMMUNITY
- Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation
- (2014) Mako Nakaya et al. IMMUNITY
- Bcl-6 directly represses the gene program of the glycolysis pathway
- (2014) Kenneth J Oestreich et al. NATURE IMMUNOLOGY
- Dysregulated Cytokine Production by Dendritic Cells Modulates B Cell Responses in the NZM2410 Mouse Model of Lupus
- (2014) Allison Sang et al. PLoS One
- Control of TFH cell numbers: why and how?
- (2013) Alvin Pratama et al. IMMUNOLOGY AND CELL BIOLOGY
- The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus
- (2013) Rachael Keating et al. NATURE IMMUNOLOGY
- Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
- (2013) Linda V Sinclair et al. NATURE IMMUNOLOGY
- Are RASopathies new monogenic predisposing conditions to the development of systemic lupus erythematosus? Case report and systematic review of the literature
- (2013) Brigitte Bader-Meunier et al. SEMINARS IN ARTHRITIS AND RHEUMATISM
- Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation
- (2012) André Ballesteros-Tato et al. IMMUNITY
- mTOR, metabolism, and the regulation of T-cell differentiation and function
- (2012) Adam T. Waickman et al. IMMUNOLOGICAL REVIEWS
- MS2 VLP-based delivery of microRNA-146a inhibits autoantibody production in lupus-prone mice
- (2012) Yang Pan et al. International Journal of Nanomedicine
- CD98 at the crossroads of adaptive immunity and cancer
- (2012) J. M. Cantor et al. JOURNAL OF CELL SCIENCE
- Interleukin-7, but Not Thymic Stromal Lymphopoietin, Plays a Key Role in the T Cell Response to Influenza A Virus
- (2012) Adam W. Plumb et al. PLoS One
- K-RAS GTPase- and B-RAF kinase-mediated T-cell tolerance defects in rheumatoid arthritis
- (2012) K. Singh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial
- (2011) Sandra V Navarra et al. LANCET
- Germinal center B and follicular helper T cells: siblings, cousins or just good friends?
- (2011) Stephen L Nutt et al. NATURE IMMUNOLOGY
- Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study
- (2010) Gabor G. Illei et al. ARTHRITIS AND RHEUMATISM
- In vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus
- (2010) Yulia Vugmeyster et al. mAbs
- A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice
- (2009) J. A. Bubier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defective B-cell response to T-dependent immunization in lupus-prone mice
- (2008) Haitao Niu et al. EUROPEAN JOURNAL OF IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More