Follicular Helper T Cells in Systemic Lupus Erythematosus: Why Should They Be Considered as Interesting Therapeutic Targets?
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Title
Follicular Helper T Cells in Systemic Lupus Erythematosus: Why Should They Be Considered as Interesting Therapeutic Targets?
Authors
Keywords
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Journal
Journal of Immunology Research
Volume 2016, Issue -, Pages 1-13
Publisher
Hindawi Limited
Online
2016-08-23
DOI
10.1155/2016/5767106
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Related references
Note: Only part of the references are listed.- Follicular Helper T Cells
- (2016) Carola G. Vinuesa et al. Annual Review of Immunology
- The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6
- (2016) Dennis Stauss et al. EMBO JOURNAL
- Increased frequency of circulating follicular helper T cells in lupus patients is associated with autoantibody production in a CD40L-dependent manner
- (2015) Huaheng Xu et al. CELLULAR IMMUNOLOGY
- A comprehensive investigation on the distribution of circulating follicular T helper cells and B cell subsets in primary Sjögren's syndrome and systemic lupus erythematosus
- (2015) K. Szabó et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Signal transducer and activator of transcription (STAT) 3 inhibition delays the onset of lupus nephritis in MRL/lpr mice
- (2015) Lindsay J. Edwards et al. CLINICAL IMMUNOLOGY
- OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response
- (2015) Clément Jacquemin et al. IMMUNITY
- ICOS Coreceptor Signaling Inactivates the Transcription Factor FOXO1 to Promote Tfh Cell Differentiation
- (2015) Erica L. Stone et al. IMMUNITY
- Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies
- (2015) Cindy S. Ma et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Cutting Edge: Circulating Plasmablasts Induce the Differentiation of Human T Follicular Helper Cells via IL-6 Production
- (2015) Konstantia-Maria Chavele et al. JOURNAL OF IMMUNOLOGY
- Circulating CXCR5+CD4+helper T cells in systemic lupus erythematosus patients share phenotypic properties with germinal center follicular helper T cells and promote antibody production
- (2015) X Zhang et al. LUPUS
- LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6
- (2015) Youn Soo Choi et al. NATURE IMMUNOLOGY
- MicroRNA-146a regulates ICOS–ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres
- (2015) Alvin Pratama et al. Nature Communications
- Circulating Follicular Helper-Like T Cells in Systemic Lupus Erythematosus: Association With Disease Activity
- (2015) Jin-Young Choi et al. Arthritis & Rheumatology
- Interleukin-21 Receptor Blockade Inhibits Secondary Humoral Responses and Halts the Progression of Preestablished Disease in the (NZB × NZW)F1 Systemic Lupus Erythematosus Model
- (2015) Ming Zhang et al. Arthritis & Rheumatology
- The association of interleukin-21 polymorphisms with interleukin-21 serum levels and risk of systemic lupus erythematosus
- (2014) Yan Lan et al. GENE
- B7RP-1 Blockade Ameliorates Autoimmunity through Regulation of Follicular Helper T Cells
- (2014) Y.-L. Hu et al. JOURNAL OF IMMUNOLOGY
- T–B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction
- (2014) Dan Liu et al. NATURE
- Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development
- (2014) Xindong Liu et al. NATURE
- Stat3 promotes IL-10 expression in lupus T cells throughtrans-activation and chromatin remodeling
- (2014) Christian M. Hedrich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defective PTEN regulation contributes to B cell hyperresponsiveness in systemic lupus erythematosus
- (2014) X.-n. Wu et al. Science Translational Medicine
- Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure
- (2013) Jing He et al. IMMUNITY
- Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses
- (2013) Michela Locci et al. IMMUNITY
- Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency
- (2013) Fabienne Mazerolles et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation
- (2013) Radhika Goenka et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility
- (2013) Heping Xu et al. NATURE
- The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression
- (2013) Dirk Baumjohann et al. NATURE IMMUNOLOGY
- MicroRNAs of the miR-17∼92 family are critical regulators of TFH differentiation
- (2013) Seung Goo Kang et al. NATURE IMMUNOLOGY
- Circulating TFH Subset Distribution Is Strongly Affected in Lupus Patients with an Active Disease
- (2013) Carole Le Coz et al. PLoS One
- Role of the PD-1 Pathway in the Immune Response
- (2012) L. V. Riella et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Functional STAT3 deficiency compromises the generation of human T follicular helper cells
- (2012) C. S. Ma et al. BLOOD
- Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene
- (2012) S E Löfgren et al. GENES AND IMMUNITY
- Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation
- (2012) André Ballesteros-Tato et al. IMMUNITY
- MS2 VLP-based delivery of microRNA-146a inhibits autoantibody production in lupus-prone mice
- (2012) Yang Pan et al. International Journal of Nanomedicine
- STAT5 Protein Negatively Regulates T Follicular Helper (Tfh) Cell Generation and Function
- (2012) Roza I. Nurieva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STAT5 is a potent negative regulator of TFHcell differentiation
- (2012) Robert J. Johnston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-21 Receptor Is Required for the Systemic Accumulation of Activated B and T Lymphocytes in MRL/MpJ-Faslpr/lpr/J Mice
- (2012) A. L. Rankin et al. JOURNAL OF IMMUNOLOGY
- TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells
- (2012) Hayato Takahashi et al. NATURE IMMUNOLOGY
- Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
- (2012) Kenneth J Oestreich et al. NATURE IMMUNOLOGY
- Inhibition of Aberrant Circulating Tfh Cell Proportions by Corticosteroids in Patients with Systemic Lupus Erythematosus
- (2012) Xuebing Feng et al. PLoS One
- Deficiency in TNFRSF13B (TACI) expands T-follicular helper and germinal center B cells via increased ICOS-ligand expression but impairs plasma cell survival
- (2012) X. Ou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Follicular Helper CD4 T Cells (TFH)
- (2011) Shane Crotty Annual Review of Immunology
- Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion
- (2011) Rimpei Morita et al. IMMUNITY
- ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6
- (2011) Youn Soo Choi et al. IMMUNITY
- Germinal Center B Cell and T Follicular Helper Cell Development Initiates in the Interfollicular Zone
- (2011) Steven M. Kerfoot et al. IMMUNITY
- B Cell-Specific Expression of B7-2 Is Required for Follicular Th Cell Function in Response to Vaccinia Virus
- (2011) S. Salek-Ardakani et al. JOURNAL OF IMMUNOLOGY
- Blockade of B7-H1 (Programmed Death Ligand 1) Enhances Humoral Immunity by Positively Regulating the Generation of T Follicular Helper Cells
- (2011) E. Hams et al. JOURNAL OF IMMUNOLOGY
- Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial
- (2011) Sandra V Navarra et al. LANCET
- Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
- (2011) Yeonseok Chung et al. NATURE MEDICINE
- Foxp3+ follicular regulatory T cells control the germinal center response
- (2011) Michelle A Linterman et al. NATURE MEDICINE
- IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation
- (2011) Danelle Eto et al. PLoS One
- Expression of inducible co-stimulator on peripheral blood T lymphocytes in patients with lupus nephritis
- (2011) Wen-Xian Li et al. RHEUMATOLOGY INTERNATIONAL
- Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus
- (2011) Sebastian Dolff et al. ARTHRITIS RESEARCH & THERAPY
- Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice
- (2010) Meera Ramanujam et al. ARTHRITIS AND RHEUMATISM
- Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study
- (2010) Gabor G. Illei et al. ARTHRITIS AND RHEUMATISM
- The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity
- (2010) Linda A. Lieberman et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Batf coordinates multiple aspects of B and T cell function required for normal antibody responses
- (2010) Briana C. Betz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Identification of New Pathogenic Players in Lupus: Autoantibody-Secreting Cells Are Present in Nephritic Kidneys of (NZBxNZW)F1 Mice
- (2010) S. Lacotte et al. JOURNAL OF IMMUNOLOGY
- IL-21 Receptor Is Critical for the Development of Memory B Cell Responses
- (2010) A. L. Rankin et al. JOURNAL OF IMMUNOLOGY
- B and T Lymphocyte Attenuator Suppresses IL-21 Production from Follicular Th Cells and Subsequent Humoral Immune Responses
- (2010) D. Kashiwakuma et al. JOURNAL OF IMMUNOLOGY
- Germinal Center T Follicular Helper Cell IL-4 Production Is Dependent on Signaling Lymphocytic Activation Molecule Receptor (CD150)
- (2010) I. Yusuf et al. JOURNAL OF IMMUNOLOGY
- In vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus
- (2010) Yulia Vugmeyster et al. mAbs
- PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells
- (2010) Kim L Good-Jacobson et al. NATURE IMMUNOLOGY
- A polymorphism withinIL21Rconfers risk for systemic lupus erythematosus
- (2009) Ryan Webb et al. ARTHRITIS AND RHEUMATISM
- MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins
- (2009) Yuanjia Tang et al. ARTHRITIS AND RHEUMATISM
- Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
- (2009) Nicholas Simpson et al. ARTHRITIS AND RHEUMATISM
- T cell CD40LG gene expression and the production of IgG by autologous B cells in systemic lupus erythematosus
- (2009) Ying Zhou et al. CLINICAL IMMUNOLOGY
- Human Dendritic Cells Induce the Differentiation of Interleukin-21-Producing T Follicular Helper-like Cells through Interleukin-12
- (2009) Nathalie Schmitt et al. IMMUNITY
- The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment
- (2009) Di Yu et al. IMMUNITY
- Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12
- (2009) Cindy S Ma et al. IMMUNOLOGY AND CELL BIOLOGY
- The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells
- (2009) Oliver Dienz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Follicular helper T cells are required for systemic autoimmunity
- (2009) Michelle A. Linterman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Raised expression of cytokine receptor gp130 subunit on peripheral lymphocytes of patients with active lupus. A useful tool for monitoring the disease activity?
- (2009) M De La Torre et al. LUPUS
- Interleukin-6 release from peripheral mononuclear cells is associated to disease activity and treatment response in patients with lupus nephritis
- (2009) Pasquale Esposito et al. LUPUS
- The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
- (2009) Nicolas Fazilleau et al. NATURE IMMUNOLOGY
- Cytokine-secreting follicular T cells shape the antibody repertoire
- (2009) R Lee Reinhardt et al. NATURE IMMUNOLOGY
- Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis
- (2009) Roberta Caruso et al. NATURE MEDICINE
- Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase
- (2009) M. Gigoux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice
- (2009) J. A. Bubier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation
- (2009) R. J. Johnston et al. SCIENCE
- Bcl6 Mediates the Development of T Follicular Helper Cells
- (2009) R. I. Nurieva et al. SCIENCE
- Association of plasma B lymphocyte stimulator levels and disease activity in systemic lupus erythematosus
- (2008) Michelle Petri et al. ARTHRITIS AND RHEUMATISM
- Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-α–producing antigen-presenting cells
- (2008) Bing Yan et al. ARTHRITIS AND RHEUMATISM
- Reduced CD4+,CD25− T cell sensitivity to the suppressive function of CD4+,CD25high,CD127−/lowregulatory T cells in patients with active systemic lupus erythematosus
- (2008) Ram Kumar Chowdary Venigalla et al. ARTHRITIS AND RHEUMATISM
- Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities
- (2008) F. Eddahri et al. BLOOD
- Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages
- (2008) Roza I. Nurieva et al. IMMUNITY
- Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE)
- (2008) M. Bonelli et al. INTERNATIONAL IMMUNOLOGY
- ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity
- (2008) Jared M. Odegard et al. JOURNAL OF EXPERIMENTAL MEDICINE
- SAP-controlled T–B cell interactions underlie germinal centre formation
- (2008) Hai Qi et al. NATURE
- Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
- (2008) John B Harley et al. NATURE GENETICS
- Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity
- (2007) Rosanne Spolski et al. Annual Review of Immunology
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