Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion

Epithelial Mesenchymal Transition in Tumor Metastasis

(2018) Vivek Mittal   Annual Review of Pathology-Mechanisms of Disease

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

(2017) Angela M. Krebs et al.   NATURE CELL BIOLOGY

The miR-200 family in ovarian cancer

(2017) Maria Koutsaki et al.   Oncotarget

QuPath: Open source software for digital pathology image analysis

(2017) Peter Bankhead et al.   Scientific Reports

EMT, cell plasticity and metastasis

(2016) Christine L. Chaffer et al.   CANCER AND METASTASIS REVIEWS

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes

(2016) Francesca Cinti et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance

(2016) Merve Mutlu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype

(2016) E Fessler et al.   ONCOGENE

The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes

(2015) Bengt-Frederik Belgardt et al.   NATURE MEDICINE

Tissue invasion and metastasis: Molecular, biological and clinical perspectives

(2015) W.G. Jiang et al.   SEMINARS IN CANCER BIOLOGY

A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics

(2015) A. Sadanandam et al.   Cancer Discovery

Inhibition of ZEB1 expression induces redifferentiation of adult human β cells expanded in vitro

(2015) Elad Sintov et al.   Scientific Reports

Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice

(2015) Jennifer E. Bruin et al.   Stem Cell Reports

The Regulatory Role of MicroRNAs in EMT and Cancer

(2015) Apostolos Zaravinos   Journal of Oncology

Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

(2014) Gaofeng Xiong et al.   BMC CANCER

Pancreatic β Cell Dedifferentiation in Diabetes and Redifferentiation following Insulin Therapy

(2014) Zhiyu Wang et al.   Cell Metabolism

Oncogenic roles of EMT-inducing transcription factors

(2014) Alain Puisieux et al.   NATURE CELL BIOLOGY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNAs in Cancer

(2013) Gianpiero Di Leva et al.   Annual Review of Pathology-Mechanisms of Disease

Distinct Properties of Cell-Type-Specific and Shared Transcription Factor Binding Sites

(2013) Jason Gertz et al.   MOLECULAR CELL

MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways

(2013) X Li et al.   ONCOGENE

Downregulated microRNA-200a promotes EMT and tumor growth through the Wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

(2013) NINGNING CONG et al.   ONCOLOGY REPORTS

Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells

(2013) M. A. Nieto   SCIENCE

MicroRNAs in Stress Signaling and Human Disease

(2012) Joshua T. Mendell et al.   CELL

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Regulation of EMT by TGFβ in cancer

(2012) Carl-Henrik Heldin et al.   FEBS LETTERS

ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression

(2012) Young-Ho Ahn et al.   JOURNAL OF CLINICAL INVESTIGATION

Short Structured RNAs with Low GC Content Are Selectively Lost during Extraction from a Small Number of Cells

(2012) Young-Kook Kim et al.   MOLECULAR CELL

Meta-Analysis of Gene Expression Signatures Defining the Epithelial to Mesenchymal Transition during Cancer Progression

(2012) Christian J. Gröger et al.   PLoS One

Reduced proliferation and enhanced migration: Two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1

(2011) Valentina Evdokimova et al.   CELL CYCLE

Functional Cooperation between Snail1 and Twist in the Regulation ofZEB1Expression during Epithelial to Mesenchymal Transition

(2011) Natàlia Dave et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   MOLECULAR BIOLOGY OF THE CELL

Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis

(2011) V Davalos et al.   ONCOGENE

Pancreatic Cancers Epigenetically Silence SIP1 and Hypomethylate and Overexpress miR-200a/200b in Association with Elevated Circulating miR-200a and miR-200b Levels

(2010) A. Li et al.   CANCER RESEARCH

The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?

(2010) Simone Brabletz et al.   EMBO REPORTS

MicroRNA Functions in Stress Responses

(2010) Anthony K.L. Leung et al.   MOLECULAR CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy

(2009) L. Adam et al.   CLINICAL CANCER RESEARCH

MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer

(2009) P. Olson et al.   GENES & DEVELOPMENT

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer

(2008) S. Spaderna et al.   CANCER RESEARCH

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY