The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes

The biological functions of miRNAs: lessons from in vivo studies

(2015) Joana A. Vidigal et al.   TRENDS IN CELL BIOLOGY

Epigenetic Regulation of the DLK1-MEG3 MicroRNA Cluster in Human Type 2 Diabetic Islets

(2014) Vasumathi Kameswaran et al.   Cell Metabolism

β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment

(2014) Philippe A. Halban et al.   DIABETES CARE

MicroRNA-200 Is Induced by Thioredoxin-interacting Protein and Regulates Zeb1 Protein Signaling and Beta Cell Apoptosis

(2014) Stephen R. Filios et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-7a regulates pancreatic β cell function

(2014) Mathieu Latreille et al.   JOURNAL OF CLINICAL INVESTIGATION

Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance

(2014) Rémy Denzler et al.   MOLECULAR CELL

mRNA Destabilization Is the Dominant Effect of Mammalian MicroRNAs by the Time Substantial Repression Ensues

(2014) Stephen W. Eichhorn et al.   MOLECULAR CELL

MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes

(2014) Amin Ardestani et al.   NATURE MEDICINE

PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors

(2014) R. Ohki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling

(2013) Su Jung Song et al.   CELL

Type 2 Diabetes and Congenital Hyperinsulinism Cause DNA Double-Strand Breaks and p53 Activity in β Cells

(2013) Sharona Tornovsky-Babeay et al.   Cell Metabolism

Evidence for Rapamycin Toxicity in Pancreatic β-Cells and a Review of the Underlying Molecular Mechanisms

(2013) Adam D. Barlow et al.   DIABETES

Global gene expression profiling of pancreatic islets in mice during streptozotocin-induced  -cell damage and pancreatic Glp-1 gene therapy

(2013) J. M. Tonne et al.   Disease Models & Mechanisms

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

(2013) Jan-Wilhelm Kornfeld et al.   NATURE

Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

(2013) Guanlan Xu et al.   NATURE MEDICINE

TALEN-based knockout library for human microRNAs

(2013) Young-Kook Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MicroRNA Expression in Alpha and Beta Cells of Human Pancreatic Islets

(2013) Dagmar Klein et al.   PLoS One

MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility

(2013) H. Hasuwa et al.   SCIENCE

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress-Mitochondrial Dialog Triggering Lipotoxic Rodent and Human  -Cell Apoptosis

(2012) D. A. Cunha et al.   DIABETES

Dysregulation of Dicer1 in Beta Cells Impairs Islet Architecture and Glucose Metabolism

(2012) Amitai D. Mandelbaum et al.   Experimental Diabetes Research

MyomiR-133 regulates brown fat differentiation through Prdm16

(2012) Mirko Trajkovski et al.   NATURE CELL BIOLOGY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Reduced Proliferation and a High Apoptotic Frequency of Pancreatic Beta Cells Contribute to Genetically-determined Diabetes Susceptibility of db/db BKS Mice

(2011) R. Puff et al.   HORMONE AND METABOLIC RESEARCH

miR-29a and miR-29b Contribute to Pancreatic  -Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)

(2011) T. J. Pullen et al.   MOLECULAR AND CELLULAR BIOLOGY

p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs

(2011) Chun-Ju Chang et al.   NATURE CELL BIOLOGY

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

(2011) Manav Korpal et al.   NATURE MEDICINE

Association of Mitotic Regulation Pathway Polymorphisms with Pancreatic Cancer Risk and Outcome

(2010) F. J. Couch et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The endoplasmic reticulum stress response in the pancreatic β-cell

(2010) A. Volchuk et al.   DIABETES OBESITY & METABOLISM

Deficiency of Atf3, an adaptive-response gene, protects islets and ameliorates inflammation in a syngeneic mouse transplantation model

(2010) E. J. Zmuda et al.   DIABETOLOGIA

Dual-specificity phosphatase 26 is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma

(2010) X Shang et al.   ONCOGENE

Gene Expression Profiles of Beta-Cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes

(2010) Lorella Marselli et al.   PLoS One

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

PH Domain-Only Protein PHLDA3 Is a p53-Regulated Repressor of Akt

(2009) Tatsuya Kawase et al.   CELL

Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax

(2009) M. D. McKenzie et al.   DIABETES

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Multiple loci identified in a genome-wide association study of prostate cancer

(2008) Gilles Thomas et al.   NATURE GENETICS

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

(2008) Eleftheria Zeggini et al.   NATURE GENETICS

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

(2008) Nika N Danial et al.   NATURE MEDICINE