Staphylococcus aureus Impairs the Function of and Kills Human Dendritic Cells via the LukAB Toxin

Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314

(2018) Kimbria J. Blake et al.   Nature Communications

Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action

(2017) Isaac P. Thomsen et al.   JOURNAL OF INFECTIOUS DISEASES

Wall teichoic acid is an essential component of Staphylococcus aureus for the induction of human dendritic cell maturation

(2017) Sung Jun Hong et al.   MOLECULAR IMMUNOLOGY

Leukocidins: staphylococcal bi-component pore-forming toxins find their receptors

(2017) András N. Spaan et al.   NATURE REVIEWS MICROBIOLOGY

Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus

(2017) Julia Uebele et al.   PLoS Pathogens

Staphylococcus aureus Esx Factors Control Human Dendritic Cell Functions Conditioning Th1/Th17 Response

(2017) Melania Cruciani et al.   Frontiers in Cellular and Infection Microbiology

Exploiting dominant‐negative toxins to combatStaphylococcus aureuspathogenesis

(2016) Tamara Reyes‐Robles et al.   EMBO REPORTS

Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus

(2016) Liana C. Chan et al.   INFECTION AND IMMUNITY

Staphylococcus aureusvaccines: Deviating from the carol

(2016) Dominique Missiakas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Humanized Mice Exhibit Increased Susceptibility toStaphylococcus aureusPneumonia

(2016) Alice Prince et al.   JOURNAL OF INFECTIOUS DISEASES

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

The Fall of a Dogma? Unexpected High T-Cell Memory Response toStaphylococcus aureusin Humans

(2015) Julia B. Kolata et al.   JOURNAL OF INFECTIOUS DISEASES

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

Staphylococcal manipulation of host immune responses

(2015) Vilasack Thammavongsa et al.   NATURE REVIEWS MICROBIOLOGY

Microarray-based identification of human antibodies againstStaphylococcus aureusantigens

(2015) Peggy Kloppot et al.   Proteomics Clinical Applications

Counter inhibition between leukotoxins attenuates Staphylococcus aureus virulence

(2015) Pauline Yoong et al.   Nature Communications

Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection

(2015) Ching Wen Tseng et al.   PLoS Pathogens

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection

(2015) Aisling F. Brown et al.   PLoS Pathogens

Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular

(2015) Jason H. Melehani et al.   PLoS Pathogens

Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage

(2015) Kipyegon Kitur et al.   PLoS Pathogens

BDCA1-Positive Dendritic Cells (DCs) Represent a Unique Human Myeloid DC Subset That Induces Innate and Adaptive Immune Responses to Staphylococcus aureus Infection

(2014) Jun-O Jin et al.   INFECTION AND IMMUNITY

Phagocytosis of Staphylococcus aureus by Human Neutrophils Prevents Macrophage Efferocytosis and Induces Programmed Necrosis

(2014) M. C. Greenlee-Wacker et al.   JOURNAL OF IMMUNOLOGY

The Bicomponent Pore-Forming Leucocidins of Staphylococcus aureus

(2014) Francis Alonzo et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element

(2014) Meredith A. Benson et al.   MOLECULAR MICROBIOLOGY

Models matter: the search for an effective Staphylococcus aureus vaccine

(2014) Wilmara Salgado-Pabón et al.   NATURE REVIEWS MICROBIOLOGY

Neutrophils Versus Staphylococcus aureus: A Biological Tug of War

(2013) András N. Spaan et al.   Annual Review of Microbiology

Staphylococcus aureus Leukotoxin ED Targets the Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection

(2013) Tamara Reyes-Robles et al.   Cell Host & Microbe

Distinct localization of the complement C5b-9 complex on Gram-positive bacteria

(2013) Evelien T. M. Berends et al.   CELLULAR MICROBIOLOGY

Staphylococcus aureus Elaborates Leukocidin AB To Mediate Escape from within Human Neutrophils

(2013) Ashley L. DuMont et al.   INFECTION AND IMMUNITY

Children with Invasive Staphylococcus aureus Disease Exhibit a Potently Neutralizing Antibody Response to the Cytotoxin LukAB

(2013) Isaac P. Thomsen et al.   INFECTION AND IMMUNITY

Integrin CD11c/CD18 α-Chain Phosphorylation Is Functionally Important

(2013) Liisa M. Uotila et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Staphylococcus aureus Phenol-Soluble Modulin Peptides Modulate Dendritic Cell Functions and Increase In Vitro Priming of Regulatory T Cells

(2013) J. Schreiner et al.   JOURNAL OF IMMUNOLOGY

Pathogen-Triggered Activation of Plasmacytoid Dendritic Cells Induces IL-10-Producing B Cells in Response to Staphylococcus aureus

(2013) M. Parcina et al.   JOURNAL OF IMMUNOLOGY

Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1

(2013) A. L. DuMont et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccine review: “Staphyloccocus aureus vaccines: Problems and prospects”

(2013) Kathrin U. Jansen et al.   VACCINE

Dendritic Cells Are Central Coordinators of the Host Immune Response to Staphylococcus aureus Bloodstream Infection

(2012) Daniela Schindler et al.   AMERICAN JOURNAL OF PATHOLOGY

Rot and SaeRS Cooperate To Activate Expression of the Staphylococcal Superantigen-Like Exoproteins

(2012) M. A. Benson et al.   JOURNAL OF BACTERIOLOGY

Staphylococcus aureus Induces Type I IFN Signaling in Dendritic Cells Via TLR9

(2012) D. Parker et al.   JOURNAL OF IMMUNOLOGY

Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome

(2012) Dirk Holzinger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

Proteolytic Cleavage Inactivates the Staphylococcus aureus Lipoteichoic Acid Synthase

(2011) M. E. Wormann et al.   JOURNAL OF BACTERIOLOGY

Community-associated meticillin-resistant Staphylococcus aureus

(2010) Frank R DeLeo et al.   LANCET

Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis

(2010) Ashley L. DuMont et al.   MOLECULAR MICROBIOLOGY

Identification of Genes Involved in Polysaccharide-Independent Staphylococcus aureus Biofilm Formation

(2010) Blaise R. Boles et al.   PLoS One

Identification of a Novel Staphylococcus aureus Two-Component Leukotoxin Using Cell Surface Proteomics

(2010) Christy L. Ventura et al.   PLoS One

Towards the immune proteome of Staphylococcus aureus – The anti-S. aureus antibody response

(2009) Silva Holtfreter et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

(2009) Yoshiyuki Minegishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SaeR Binds a Consensus Sequence within Virulence Gene Promoters to Advance USA300 Pathogenesis

(2009) Tyler K. Nygaard et al.   JOURNAL OF INFECTIOUS DISEASES

Waves of resistance: Staphylococcus aureus in the antibiotic era

(2009) Henry F. Chambers et al.   NATURE REVIEWS MICROBIOLOGY

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

(2009) Robin R. Craven et al.   PLoS One

Prevalence ofagrDysfunction among ColonizingStaphylococcus aureusStrains

(2008) Bo Shopsin et al.   JOURNAL OF INFECTIOUS DISEASES