DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair

Arpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein Structures

(2017) Harry C Jubb et al.   JOURNAL OF MOLECULAR BIOLOGY

The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis

(2015) Nicholas Jette et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle

(2014) Anthony J. Davis et al.   NUCLEIC ACIDS RESEARCH

CryoEM and image sorting for flexible protein/DNA complexes

(2013) Seth A. Villarreal et al.   JOURNAL OF STRUCTURAL BIOLOGY

mTOR kinase structure, mechanism and regulation

(2013) Haijuan Yang et al.   NATURE

N-terminal constraint activates the catalytic subunit of the DNA-dependent protein kinase in the absence of DNA or Ku

(2011) K. Meek et al.   NUCLEIC ACIDS RESEARCH

Multi-crystal anomalous diffraction for low-resolution macromolecular phasing

(2010) Qun Liu et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Rapid model building of α-helices in electron-density maps

(2010) Thomas C. Terwilliger   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation

(2010) Tracey A. Dobbs et al.   DNA REPAIR

DNA-PKcs deficiency in human: long predicted, finally found

(2009) Mirjam van der Burg et al.   Current Opinion in Allergy and Clinical Immunology

Ku and DNA-dependent Protein Kinase Dynamic Conformations and Assembly Regulate DNA Binding and the Initial Non-homologous End Joining Complex

(2009) Michal Hammel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats

(2009) Bancinyane L. Sibanda et al.   NATURE

The Ku80 Carboxy Terminus Stimulates Joining and Artemis-Mediated Processing of DNA Ends

(2008) E. Weterings et al.   MOLECULAR AND CELLULAR BIOLOGY

Cryo-EM Structure of the DNA-Dependent Protein Kinase Catalytic Subunit at Subnanometer Resolution Reveals α Helices and Insight into DNA Binding

(2008) Dewight R. Williams et al.   STRUCTURE