Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex

Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining

(2016) Guangqing Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins

(2015) Arijit Dutta et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The structural basis of XRCC1-mediated DNA repair

(2015) Robert E. London   DNA REPAIR

Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines

(2015) Nguyen Ngoc Hoa et al.   GENES TO CELLS

The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome

(2015) Pavana M. Hegde et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells

(2015) Aashish Soni et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

(2015) Raphael Ceccaldi et al.   NATURE

Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

(2015) M. Raschle et al.   SCIENCE

Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

(2015) Agnel Sfeir et al.   TRENDS IN BIOCHEMICAL SCIENCES

Homology and enzymatic requirements of microhomology-dependent alternative end joining

(2015) S Sharma et al.   Cell Death & Disease

DNA end resection is needed for the repair of complex lesions in G1-phase human cells

(2014) Nicole B Averbeck et al.   CELL CYCLE

Alternative end-joining pathway(s): Bricolage at DNA breaks

(2014) Philippe Frit et al.   DNA REPAIR

RPA antagonizes microhomology-mediated repair of DNA double-strand breaks

(2014) Sarah K Deng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair

(2014) Ismail Abdou et al.   NUCLEIC ACIDS RESEARCH

Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?

(2014) Mireille Bétermier et al.   PLoS Genetics

Diverse Mechanisms of Somatic Structural Variations in Human Cancer Genomes

(2013) Lixing Yang et al.   CELL

Biological Consequences of Radiation-induced DNA Damage: Relevance to Radiotherapy

(2013) M.E. Lomax et al.   CLINICAL ONCOLOGY

Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitylation after degradation of poly(ADP-ribose)

(2013) L. Wei et al.   JOURNAL OF CELL SCIENCE

Fanconi Anemia Group J Helicase and MRE11 Nuclease Interact To Facilitate the DNA Damage Response

(2013) A. N. Suhasini et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

(2013) Atsushi Shibata et al.   MOLECULAR CELL

DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice

(2013) A. Schipler et al.   NUCLEIC ACIDS RESEARCH

Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins

(2013) M. L. Hegde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

(2013) L. N. Truong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage

(2012) Birgitte B Olsen et al.   BMC MOLECULAR BIOLOGY

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

(2012) Katharina Schlacher et al.   CANCER CELL

X-Ray Repair Cross Complementing Protein 1 in Base Excision Repair

(2012) Audun Hanssen-Bauer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)

(2012) C. Boboila et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microhomology Directs Diverse DNA Break Repair Pathways and Chromosomal Translocations

(2012) Diana D. Villarreal et al.   PLoS Genetics

CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair

(2011) Cecilia E. Ström et al.   DNA REPAIR

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

Human Mre11/Human Rad50/Nbs1 and DNA Ligase IIIα/XRCC1 Protein Complexes Act Together in an Alternative Nonhomologous End Joining Pathway

(2011) Julie Della-Maria et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining inIghgenes

(2011) Huseyin Saribasak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of homologous recombination in radiation-induced double-strand break repair

(2011) Penny A. Jeggo et al.   RADIOTHERAPY AND ONCOLOGY

Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair

(2011) Michael Weinfeld et al.   TRENDS IN BIOCHEMICAL SCIENCES

XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair

(2010) Jason L. Parsons et al.   DNA REPAIR

Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

(2010) Eleni P Mimitou et al.   EMBO JOURNAL

Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair

(2010) Martijn S. Luijsterburg et al.   JOURNAL OF CELL BIOLOGY

CtIP promotes microhomology-mediated alternative end joining during class-switch recombination

(2010) Mieun Lee-Theilen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies

(2010) Wael Y. Mansour et al.   NUCLEIC ACIDS RESEARCH

Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions

(2010) Amy Marie Yu et al.   NUCLEIC ACIDS RESEARCH

Xrcc1-dependent and Ku-dependent DNA double-strand break repair kinetics in Arabidopsis plants

(2010) Cyril Charbonnel et al.   PLANT JOURNAL

The DNA repair protein NBS1 influences the base excision repair pathway

(2009) D. Sagan et al.   CARCINOGENESIS

Localization of X-ray cross complementing gene 1 protein in the nuclear matrix is controlled by casein kinase II-dependent phosphorylation in response to oxidative damage

(2009) Yoshiko Kubota et al.   DNA REPAIR

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

(2009) Anyong Xie et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ionizing Radiation Induces Microhomology-Mediated End Joiningin transin Yeast and Mammalian Cells

(2009) Zorica Scuric et al.   RADIATION RESEARCH

Intrinsic Disorder in Protein Interactions: Insights From a Comprehensive Structural Analysis

(2009) Jessica H. Fong et al.   PLoS Computational Biology

Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2

(2008) Wenqi Wu et al.   DNA REPAIR

Microhomologies and interspersed repeat elements at genomic breakpoints in chronic myeloid leukemia

(2008) Elia Mattarucchi et al.   GENES CHROMOSOMES & CANCER

MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

(2008) Mitch McVey et al.   TRENDS IN GENETICS