Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans

Oncogenic Kras-Induced GM-CSF Production Promotes the Development of Pancreatic Neoplasia

(2012) Yuliya Pylayeva-Gupta et al.   CANCER CELL

Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression

(2011) Akihisa Fukuda et al.   CANCER CELL

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

(2011) Marina Lesina et al.   CANCER CELL

Notch Signaling Activated by Replication Stress-Induced Expression of Midkine Drives Epithelial-Mesenchymal Transition and Chemoresistance in Pancreatic Cancer

(2011) C. Gungor et al.   CANCER RESEARCH

Notch signaling: simplicity in design, versatility in function

(2011) E. R. Andersson et al.   DEVELOPMENT

Dendritic Cells Promote Pancreatic Viability in Mice With Acute Pancreatitis

(2011) Andrea S. Bedrosian et al.   GASTROENTEROLOGY

Deletion of Rb Accelerates Pancreatic Carcinogenesis by Oncogenic Kras and Impairs Senescence in Premalignant Lesions

(2011) Catherine Carrière et al.   GASTROENTEROLOGY

Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice

(2011) Eleni Maniati et al.   JOURNAL OF CLINICAL INVESTIGATION

The redox protein HMGB1 regulates cell death and survival in cancer treatment

(2010) Daolin Tang et al.   Autophagy

PTEN Loss Accelerates KrasG12D-Induced Pancreatic Cancer Development

(2010) R. Hill et al.   CANCER RESEARCH

Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression

(2010) Martin Grimm et al.   EUROPEAN JOURNAL OF CANCER

Stromal biology and therapy in pancreatic cancer

(2010) A. Neesse et al.   GUT

Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance

(2010) Julien Cherfils-Vicini et al.   JOURNAL OF CLINICAL INVESTIGATION

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9

(2010) Cristiana Guiducci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Treatment Failure of a TLR-7 Agonist Occurs Due to Self-Regulation of Acute Inflammation and Can Be Overcome by IL-10 Blockade

(2010) H. Lu et al.   JOURNAL OF IMMUNOLOGY

In Hepatic Fibrosis, Liver Sinusoidal Endothelial Cells Acquire Enhanced Immunogenicity

(2010) M. K. Connolly et al.   JOURNAL OF IMMUNOLOGY

Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras

(2009) Catherine Carrière et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Postresection survival outcomes of pancreatic cancer according to demographic factors and socio-economic status

(2009) Y. Kuhn et al.   EJSO

Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor

(2009) Michael K. Connolly et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

(2008) R. F. Hwang et al.   CANCER RESEARCH

Risk of hepatobiliary and pancreatic cancers after hepatitis C virus infection: A population-based study of U.S. veterans

(2008) Hashem B. El-Serag et al.   HEPATOLOGY

Murine CD146 is widely expressed on endothelial cells and is recognized by the monoclonal antibody ME-9F1

(2008) Arnhild Schrage et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Integrated Regulation of Toll-like Receptor Responses by Notch and Interferon-γ Pathways

(2008) Xiaoyu Hu et al.   IMMUNITY

Association Between Hepatitis B Virus and Pancreatic Cancer

(2008) Manal M. Hassan et al.   JOURNAL OF CLINICAL ONCOLOGY

Role of Toll-like receptors in gastrointestinal malignancies

(2008) M Fukata et al.   ONCOGENE

Radiation therapy and Toll-like receptor signaling: implications for the treatment of cancer

(2008) R E Roses et al.   ONCOGENE

Toll-like receptors and immune regulation: implications for cancer therapy

(2008) R-F Wang et al.   ONCOGENE

TLR signaling by tumor and immune cells: a double-edged sword

(2008) B Huang et al.   ONCOGENE

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

(2008) J.-P. De La O et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA