Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments

The antioxidant xanthorrhizol prevents amyloid-β-induced oxidative modification and inactivation of neprilysin

(2018) Chol Seung Lim et al.   BIOSCIENCE REPORTS

A polysaccharide from green tea ( Camellia sinensis L.) protects human retinal endothelial cells against hydrogen peroxide-induced oxidative injury and apoptosis

(2018) Yitao Yan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Cyanthin Diterpenoid and Sesterterpene Constituents of Hericium erinaceus Mycelium Ameliorate Alzheimer’s Disease-Related Pathologies in APP/PS1 Transgenic Mice

(2018) Tsai-Teng Tzeng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer’s Disease

(2018) D. Allan Butterfield et al.   JOURNAL OF ALZHEIMERS DISEASE

Extending a Systems Model of the APP Pathway: Separation ofβ- andγ-Secretase Sequential Cleavage Steps of APP

(2018) Eline M. T. van Maanen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer’s disease

(2018) Jian Bao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients

(2018) Julian H. Birnbaum et al.   Stem Cell Research

Liraglutide Activates the Nrf2/HO-1 Antioxidant Pathway and Protects Brain Nerve Cells against Cerebral Ischemia in Diabetic Rats

(2018) Caihong Deng et al.   Computational Intelligence and Neuroscience

Licochalcone A Upregulates Nrf2 Antioxidant Pathway and Thereby Alleviates Acetaminophen-Induced Hepatotoxicity

(2018) Hongming Lv et al.   Frontiers in Pharmacology

Impairment of Several Immune Functions and Redox State in Blood Cells of Alzheimer’s Disease Patients. Relevant Role of Neutrophils in Oxidative Stress

(2018) Carmen Vida et al.   Frontiers in Immunology

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

Daphnetin-mediated Nrf2 antioxidant signaling pathways ameliorate tert-butyl hydroperoxide ( t -BHP)-induced mitochondrial dysfunction and cell death

(2017) Hongming Lv et al.   FREE RADICAL BIOLOGY AND MEDICINE

The ginsenoside metabolite compound K inhibits growth, migration and stemness of glioblastoma cells

(2017) Sanghun Lee et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

BACE1 Function and Inhibition: Implications of Intervention in the Amyloid Pathway of Alzheimer’s Disease Pathology

(2017) Gerald Koelsch   MOLECULES

Resveratrol Attenuates the Cytotoxicity Induced by Amyloid-β1–42 in PC12 Cells by Upregulating Heme Oxygenase-1 via the PI3K/Akt/Nrf2 Pathway

(2017) Yang Hui et al.   NEUROCHEMICAL RESEARCH

Dominant negative effect of the loss-of-function γ-secretase mutants on the wild-type enzyme through heterooligomerization

(2017) Rui Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats

(2017) Ali R. Alhoshani et al.   BMC Nephrology

Cilostazol Suppresses Aβ-induced Neurotoxicity in SH-SY5Y Cells through Inhibition of Oxidative Stress and MAPK Signaling Pathway

(2017) Tatsunori Oguchi et al.   Frontiers in Aging Neuroscience

The Nrf2/Keap1/ARE Pathway and Oxidative Stress as a Therapeutic Target in Type II Diabetes Mellitus

(2017) Joshua A. David et al.   Journal of Diabetes Research

Ethyl Acetate Extract Components of Bushen-Yizhi Formula Provides Neuroprotection against Scopolamine-induced Cognitive Impairment

(2017) Shi-Jie Zhang et al.   Scientific Reports

Targeting Insulin-Degrading Enzyme to Treat Type 2 Diabetes Mellitus

(2016) Wei-Jen Tang   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner

(2015) Sandeep K. Sharma et al.   Scientific Reports

Bushen-Yizhi formula ameliorates cognition deficits and attenuates oxidative stress-related neuronal apoptosis in scopolamine-induced senescence in mice

(2014) XUE-QIN HOU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Amyloid-clearing proteins and their epigenetic regulation as a therapeutic target in Alzheimer’s disease

(2014) Natalia N. Nalivaeva et al.   Frontiers in Aging Neuroscience

Effects of Magnolol on Impairment of Learning and Memory Abilities Induced by Scopolamine in Mice

(2013) Yang-si Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease

(2013) Kamran Honarnejad et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system

(2013) Hee Jin Kim et al.   Journal of Ginseng Research

Current Evaluation of the Millennium Phytomedicine- Ginseng (II): Collected Chemical Entities, Modern Pharmacology, and Clinical Applications Emanated from Traditional Chinese Medicine

(2009) Lee Jia et al.   CURRENT MEDICINAL CHEMISTRY