Natural products from anaerobes

Biosynthesis, Synthesis, and Activities of Barnesin A, a NRPS-PKS Hybrid Produced by an Anaerobic Epsilonproteobacterium

(2018) Maja Rischer et al.   ACS Chemical Biology

Discovery of small molecule protease inhibitors by investigating a widespread human gut bacterial biosynthetic pathway

(2018) Benjamin A. Schneider et al.   TETRAHEDRON

Genome Editing Reveals Novel Thiotemplated Assembly of Polythioamide Antibiotics in Anaerobic Bacteria

(2018) Kyle Dunbar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular beacons to identify gifted microbes for genome mining

(2017) Richard H Baltz   JOURNAL OF ANTIBIOTICS

Synthetic biology, genome mining, and combinatorial biosynthesis of NRPS-derived antibiotics: a perspective

(2017) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification

(2017) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

The industrial anaerobe Clostridium acetobutylicum uses polyketides to regulate cellular differentiation

(2017) Nicolaus A. Herman et al.   Nature Communications

Stress-driven discovery of a cryptic antibiotic produced by Streptomyces sp. WU20 from Kueishantao hydrothermal vent with an integrated metabolomics strategy

(2016) Yutong Shi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Gifted microbes for genome mining and natural product discovery

(2016) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

An Unusual Stress Metabolite from a Hydrothermal Vent Fungus Aspergillus sp. WU 243 Induced by Cobalt

(2016) Chihong Ding et al.   MOLECULES

The evolution of genome mining in microbes – a review

(2016) Nadine Ziemert et al.   NATURAL PRODUCT REPORTS

Bioactive natural products from novel microbial sources

(2015) Victoria L. Challinor et al.   Annals of the New York Academy of Sciences

Mode of action of closthioamide: the first member of the polythioamide class of bacterial DNA gyrase inhibitors

(2015) Alina Iulia Chiriac et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Plant pathogenic anaerobic bacteria use aromatic polyketides to access aerobic territory

(2015) G. Shabuer et al.   SCIENCE

Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors

(2015) Marton Siklos et al.   Acta Pharmaceutica Sinica B

Discovery of Clostrubin, an Exceptional Polyphenolic Polyketide Antibiotic from a Strictly Anaerobic Bacterium

(2014) Sacha Pidot et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria

(2014) Anne-Catrin Letzel et al.   BMC GENOMICS

A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics

(2014) Mohamed S. Donia et al.   CELL

The structural biology of phenazine biosynthesis

(2014) Wulf Blankenfeldt et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Antiterminator-Mediated Unveiling of Cryptic Polythioamides in an Anaerobic Bacterium

(2012) Swantje Behnken et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diversity and Natural Functions of Antibiotics Produced by Beneficial and Plant Pathogenic Bacteria

(2012) Jos M. Raaijmakers et al.   Annual Review of Phytopathology

Anaerobic bacteria as producers of antibiotics

(2012) Swantje Behnken et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Synthesis of Bioactive Natural Products as Protein Inhibitors

(2012) Hiroyuki KONNO   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Ammonificins C and D, Hydroxyethylamine Chromene Derivatives from a Cultured Marine Hydrothermal Vent Bacterium, Thermovibrio ammonificans

(2012) Eric H. Andrianasolo et al.   Marine Drugs

A genomic approach to the cryptic secondary metabolome of the anaerobic world

(2012) Anne-Catrin Letzel et al.   NATURAL PRODUCT REPORTS

Metabolic engineering of Clostridium acetobutylicum: recent advances to improve butanol production

(2011) Tina Lütke-Eversloh et al.   CURRENT OPINION IN BIOTECHNOLOGY

An ecological perspective of microbial secondary metabolism

(2011) Jonathan O’Brien et al.   CURRENT OPINION IN BIOTECHNOLOGY

Clostridiolysin S, a Post-translationally Modified Biotoxin fromClostridium botulinum

(2010) David J. Gonzalez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human gut microbiome: the second genome of human body

(2010) Baoli Zhu et al.   Protein & Cell

Naphthalecin, a Novel Antibiotic Produced by the Anaerobic Bacterium, Sporotalea colonica sp. nov.

(2009) Masami Ezaki et al.   JOURNAL OF ANTIBIOTICS

Ammonificins A and B, Hydroxyethylamine Chroman Derivatives from a Cultured Marine Hydrothermal Vent Bacterium,Thermovibrio ammonificans

(2009) Eric H. Andrianasolo et al.   JOURNAL OF NATURAL PRODUCTS

Antibiotics as signals that trigger specific bacterial responses

(2008) Alicia Fajardo et al.   CURRENT OPINION IN MICROBIOLOGY