Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation

Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats

(2018) Jinlin Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Studies on the hepatoprotective effect of fucoidans from brown algae Kjellmaniella crassifolia

(2018) Shu Liu et al.   CARBOHYDRATE POLYMERS

Detoxifying effect of pyridoxine on acetaminophen-induced hepatotoxicity via suppressing oxidative stress injury

(2018) Taehyun Roh et al.   FOOD AND CHEMICAL TOXICOLOGY

The role of apoptosis in acetaminophen hepatotoxicity

(2018) Hartmut Jaeschke et al.   FOOD AND CHEMICAL TOXICOLOGY

Dietary α-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis

(2018) Xiao-tong Yan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice

(2018) Shenhai Gong et al.   JOURNAL OF HEPATOLOGY

Licochalcone A Upregulates Nrf2 Antioxidant Pathway and Thereby Alleviates Acetaminophen-Induced Hepatotoxicity

(2018) Hongming Lv et al.   Frontiers in Pharmacology

Hepatoprotective Effects of Lactobacillus on Carbon Tetrachloride-Induced Acute Liver Injury in Mice

(2018) Xiaoyong Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phycochemical Constituents and Biological Activities of Fucus spp.

(2018) Marcelo Catarino et al.   Marine Drugs

Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat

(2017) Lin Luo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Expression of muscarinic acetylcholine receptors in hepatocytes from rat fibrotic liver

(2017) Lin Luo et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Protective role of p53 in acetaminophen hepatotoxicity

(2017) Yazhen Huo et al.   FREE RADICAL BIOLOGY AND MEDICINE

2,3,7,8-Tetrachlorodibenzo- p -dioxin (TCDD) induces hepatic stellate cell (HSC) activation and liver fibrosis in C57BL6 mouse via activating Akt and NF-κB signaling pathways

(2017) Ming Han et al.   TOXICOLOGY LETTERS

Induction of heat shock protein 27 by bicyclol attenuates d -galactosamine/lipopolysaccharide-induced liver injury

(2016) Hui-Juan Dai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

ZT-25, a new vacuolar H+-ATPase inhibitor, induces apoptosis and protective autophagy through ROS generation in HepG2 cells

(2016) Yapeng Lu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice

(2016) Hong-Min Ni et al.   JOURNAL OF HEPATOLOGY

Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential

(2016) Kuo Du et al.   Redox Biology

Therapies from Fucoidan: An Update

(2015) Janet Fitton et al.   Marine Drugs

Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1–p53 signaling pathways

(2015) Ying Wang et al.   TOXICOLOGY LETTERS

Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases

(2013) Hemant Kumar et al.   NATURAL PRODUCT REPORTS

NRF2-regulation in brain health and disease: Implication of cerebral inflammation

(2013) Mats Sandberg et al.   NEUROPHARMACOLOGY

Protective effect of fucoidan against acetaminophen-induced liver injury

(2012) Sang-Won Hong et al.   ARCHIVES OF PHARMACAL RESEARCH

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

(2012) Mitchell R. McGill et al.   JOURNAL OF CLINICAL INVESTIGATION

c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity

(2010) Chieko Saito et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Protective effect of bicyclol on tetracycline-induced fatty liver in mice

(2009) Hong-Yan Yu et al.   TOXICOLOGY

Deletion of Apoptosis Signal-Regulating Kinase 1 Attenuates Acetaminophen-Induced Liver Injury by Inhibiting c-Jun N-Terminal Kinase Activation

(2008) Hayato Nakagawa et al.   GASTROENTEROLOGY

Safety and Effectiveness of Acetadote for Acetaminophen Toxicity

(2008) Allyson J. Whyte et al.   JOURNAL OF EMERGENCY MEDICINE