CLDN18.1 attenuates malignancy and related signaling pathways of lung adenocarcinoma in vivo and in vitro

Claudin-18–mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis

(2018) Beiyun Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

IGF-IR signaling in epithelial to mesenchymal transition and targeting IGF-IR therapy: overview and new insights

(2017) Heming Li et al.   Molecular Cancer

Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling

(2016) Xing-Ding Zhang et al.   CANCER CELL

YAP Promotes Malignant Progression ofLkb1-Deficient Lung Adenocarcinoma through Downstream Regulation of Survivin

(2015) Wenjing Zhang et al.   CANCER RESEARCH

TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells

(2015) Megan L. Finch-Edmondson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

YAP is a critical oncogene in human cholangiocarcinoma

(2015) Tiemin Pei et al.   Oncotarget

Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

(2015) Minchul Kim et al.   Cell Reports

Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer

(2014) Claudia Fumarola et al.   BIOCHEMICAL PHARMACOLOGY

An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non-Small Cell Lung Cancer

(2014) S. Noguchi et al.   CLINICAL CANCER RESEARCH

Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer

(2014) Patrick Micke et al.   INTERNATIONAL JOURNAL OF CANCER

The Hippo-YAP signaling pathway and contact inhibition of growth

(2014) Barry M. Gumbiner et al.   JOURNAL OF CELL SCIENCE

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1

(2013) R. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated Transcriptomic and Epigenomic Analysis of Primary Human Lung Epithelial Cell Differentiation

(2013) Crystal N. Marconett et al.   PLoS Genetics

Claudins and alveolar epithelial barrier function in the lung

(2012) James A. Frank   Annals of the New York Academy of Sciences

Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP

(2012) Katrin Straßburger et al.   DEVELOPMENTAL BIOLOGY

The N-terminal Phosphodegron Targets TAZ/WWTR1 Protein for SCFβ-TrCP-dependent Degradation in Response to Phosphatidylinositol 3-Kinase Inhibition

(2012) Wei Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

(2012) Karen Tumaneng et al.   NATURE CELL BIOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Claudin-18 gene structure, regulation, and expression is evolutionary conserved in mammals

(2011) Özlem Türeci et al.   GENE

mTOR Complex 2 Targets Akt for Proteasomal Degradation via Phosphorylation at the Hydrophobic Motif

(2011) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Claudin-18 Is an Early-Stage Marker of Pancreatic Carcinogenesis

(2011) Mariko Tanaka et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size

(2011) M. Xin et al.   Science Signaling

Claudin Family of Proteins and Cancer: An Overview

(2010) Amar B. Singh et al.   Journal of Oncology

A Small Molecule Disruptor of Rb/Raf-1 Interaction Inhibits Cell Proliferation, Angiogenesis, and Growth of Human Tumor Xenografts in Nude Mice

(2008) R. Kinkade et al.   CANCER RESEARCH

Claudin-18 Splice Variant 2 Is a Pan-Cancer Target Suitable for Therapeutic Antibody Development

(2008) U. Sahin et al.   CLINICAL CANCER RESEARCH