Mitochondrial pathway of apoptosis and necrosis contribute to tenofovir disoproxil fumarate–induced renal damage in rats

Establishment of HK-2 Cells as a Relevant Model to Study Tenofovir-Induced Cytotoxicity

(2017) Rachel Murphy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The PARP family: insights into functional aspects of poly (ADP-ribose) polymerase-1 in cell growth and survival

(2016) T. Jubin et al.   CELL PROLIFERATION

The effect of poly (ADP-ribose) polymerase inhibition on aminoglycoside-induced acute tubular necrosis in rats

(2016) Alexander Biro et al.   CLINICAL NEPHROLOGY

Melatonin enhances mitochondrial ATP synthesis, reduces reactive oxygen species formation, and mediates translocation of the nuclear erythroid 2-related factor 2 resulting in activation of phase-2 antioxidant enzymes (γ-GCS, HO-1, NQO1) in ultraviolet rad

(2016) Konrad Kleszczyński et al.   JOURNAL OF PINEAL RESEARCH

Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling

(2015) Lei Zhao et al.   JOURNAL OF PINEAL RESEARCH

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

(2014) Ke Ding et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Dysfunction and Electron Transport Chain Complex Defect in a Rat Model of Tenofovir Disoproxil Fumarate Nephrotoxicity

(2014) Hemalatha Ramamoorthy et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Beetroot (Beta vulgarisL.) Extract Ameliorates Gentamicin-Induced Nephrotoxicity Associated Oxidative Stress, Inflammation, and Apoptosis in Rodent Model

(2014) Ali A. El Gamal et al.   MEDIATORS OF INFLAMMATION

Evidence for the roles of oxidative stress, nitrosative stress and Nf-Kb activation in Tenofovir Disoproxil Fumarate (TDF) induced renal damage in rats

(2013) Hemalatha Ramamoorthy et al.   BMC INFECTIOUS DISEASES

The protective effects of selenium on cadmium-induced oxidative stress and apoptosis via mitochondria pathway in mice kidney

(2013) Yang Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Association Between Antiretroviral Exposure and Renal Impairment Among HIV-Positive Persons With Normal Baseline Renal Function: the D:A:D Studya

(2013) L. Ryom et al.   JOURNAL OF INFECTIOUS DISEASES

Melatonin induces apoptosis through a caspase-dependent but reactive oxygen species-independent mechanism in human leukemia Molt-3 cells

(2013) Juan Perdomo et al.   JOURNAL OF PINEAL RESEARCH

Association of tenofovir exposure with kidney disease risk in HIV infection

(2012) Rebecca Scherzer et al.   AIDS

Renal Impairment in Patients Receiving a Tenofovir-cART Regimen

(2012) Isabelle Poizot-Martin et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Tenofovir-Associated Kidney Toxicity in HIV-Infected Patients: A Review of the Evidence

(2011) Andrew M. Hall et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis

(2010) Gabriel Loor et al.   FREE RADICAL BIOLOGY AND MEDICINE

Incidence of proximal renal tubular dysfunction in patients on tenofovir disoproxil fumarate

(2010) K J Quinn et al.   INTERNATIONAL JOURNAL OF STD & AIDS

Tenofovir-induced kidney disease: an acquired renal tubular mitochondriopathy

(2010) Mark A. Perazella   KIDNEY INTERNATIONAL

Tenofovir nephrotoxicity: acute tubular necrosis with distinctive clinical, pathological, and mitochondrial abnormalities

(2010) Leal C. Herlitz et al.   KIDNEY INTERNATIONAL

An Integrative Overview on the Mechanisms Underlying the Renal Tubular Cytotoxicity of Gentamicin

(2010) Y. Quiros et al.   TOXICOLOGICAL SCIENCES

The role of chemokines in progressive renal disease

(2009) Carla Zoja   Frontiers in Bioscience-Landmark

Neutrophils in acute kidney injury: not neutral any more

(2009) Subhashini Bolisetty et al.   KIDNEY INTERNATIONAL

Tenofovir renal toxicity targets mitochondria of renal proximal tubules

(2009) James J Kohler et al.   LABORATORY INVESTIGATION

Melatonin Is a Potent Inhibitor for Myeloperoxidase†

(2008) Semira Galijasevic et al.   BIOCHEMISTRY

A Role for galectin-3 in renal tissue damage triggered by ischemia and reperfusion injury

(2008) Ana Paula Fernandes Bertocchi et al.   TRANSPLANT INTERNATIONAL