An Integrative Overview on the Mechanisms Underlying the Renal Tubular Cytotoxicity of Gentamicin

Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway

(2010) Ana I. Morales et al.   KIDNEY INTERNATIONAL

Nitric oxide and oxidative stress in vascular disease

(2010) Ulrich Förstermann   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Gentamicin-induced preconditioning of proximal tubular LLC-PK1 cells stimulates nitric oxide production but not the synthesis of heat shock protein

(2009) E.A. Pessoa et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats

(2009) Srinivasan Kalayarasan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Differential roles of dihydropyridine calcium antagonist nifedipine, nitrendipine and amlodipine on gentamicin-induced renal tubular toxicity in rats

(2009) Jin Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitochondria and Energetic Depression in Cell Pathophysiology

(2009) Enn Seppet et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CTGF Promotes Inflammatory Cell Infiltration of the Renal Interstitium by Activating NF- B

(2009) E. Sanchez-Lopez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Potential utility of PPARα activation in the prevention of ischemic and drug-induced acute renal damage

(2009) Francisco J. Lopez-Hernandez et al.   KIDNEY INTERNATIONAL

Transgenic expression of proximal tubule peroxisome proliferator–activated receptor-α in mice confers protection during acute kidney injury

(2009) Shenyang Li et al.   KIDNEY INTERNATIONAL

Decreased renal uptake of 99mTc-DMSA in patients with tubular proteinuria

(2009) Beom Hee Lee et al.   PEDIATRIC NEPHROLOGY

The Calpain, Caspase 12, Caspase 3 Cascade Leading to Apoptosis Is Altered in F508del-CFTR Expressing Cells

(2009) Mathieu Kerbiriou et al.   PLoS One

Multiplexed assay panel of cytotoxicity in HK-2 cells for detection of renal proximal tubule injury potential of compounds

(2009) Yang Wu et al.   TOXICOLOGY IN VITRO

Recent Updates on the Calcium-Sensing Receptor as a Drug Target

(2008) Ritu Trivedi et al.   CURRENT MEDICINAL CHEMISTRY

TRPV4 enhances the cellular uptake of aminoglycoside antibiotics

(2008) T. Karasawa et al.   JOURNAL OF CELL SCIENCE

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

Antioxidation and anti-inflammation by haem oxygenase-1 contribute to protection by tetramethylpyrazine against gentamicin-induced apoptosis in murine renal tubular cells

(2008) Y.-M. Sue et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Outcomes of Stage 3–5 Chronic Kidney Disease before End-Stage Renal Disease at a Single Center in Taiwan

(2008) Yen-Ling Chiu et al.   NEPHRON CLINICAL PRACTICE

Prostacyclin protects renal tubular cells from gentamicin-induced apoptosis via a PPARα-dependent pathway

(2007) Y.-H. Hsu et al.   KIDNEY INTERNATIONAL