The regulatory roles of glycosphingolipid‐enriched lipid rafts in immune systems

Glycan-Glycan Interaction Determines Shigella Tropism toward Human T Lymphocytes

(2018) Ilia Belotserkovsky et al.   mBio

Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity

(2017) Masahiro Nagata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucosylceramide Synthase Is Involved in Development of Invariant Natural Killer T Cells

(2017) Zoran V. Popovic et al.   Frontiers in Immunology

Natural Killer T Cells: An Ecological Evolutionary Developmental Biology Perspective

(2017) Amrendra Kumar et al.   Frontiers in Immunology

Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation

(2016) Tina Garofalo et al.   Autophagy

The ganglioside GM1 interacts with the serotonin 1A receptor via the sphingolipid binding domain

(2016) Xavier Prasanna et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lipoarabinomannan binding to lactosylceramide in lipid rafts is essential for the phagocytosis of mycobacteria by human neutrophils

(2016) H. Nakayama et al.   Science Signaling

Lipoarabinomannan binding to lactosylceramide in lipid rafts is essential for the phagocytosis of mycobacteria by human neutrophils

(2016) H. Nakayama et al.   Science Signaling

G protein–membrane interactions I: Gαi1 myristoyl and palmitoyl modifications in protein–lipid interactions and its implications in membrane microdomain localization

(2015) Rafael Álvarez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Distinct selectivity of gangliosides required for CD4 + T and CD8 + T cell activation

(2015) Jin-ichi Inokuchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

MHC class II association with lipid rafts on the antigen presenting cell surface

(2015) Howard A. Anderson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Properties and functions of lactosylceramide from mouse neutrophils

(2015) K. Iwabuchi et al.   GLYCOBIOLOGY

Transbilayer distribution of lipids at nano scale

(2015) M. Murate et al.   JOURNAL OF CELL SCIENCE

Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans

(2015) Kazuhisa Iwabuchi et al.   MEDIATORS OF INFLAMMATION

Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation

(2014) Paola Matarrese et al.   Autophagy

T cell subsets and their role in the pathogenesis of rheumatic disease

(2014) Alison M. Gizinski et al.   CURRENT OPINION IN RHEUMATOLOGY

The Identification of the Endogenous Ligands of Natural Killer T Cells Reveals the Presence of Mammalian α-Linked Glycosylceramides

(2014) Lisa Kain et al.   IMMUNITY

Lipids rule: resetting lipid metabolism restores T cell function in systemic lupus erythematosus

(2014) Yoko Kidani et al.   JOURNAL OF CLINICAL INVESTIGATION

Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients

(2014) Georgia McDonald et al.   JOURNAL OF CLINICAL INVESTIGATION

Francisella Targets Cholesterol-Rich Host Cell Membrane Domains for Entry into Macrophages

(2014) B. Tamilselvam et al.   JOURNAL OF IMMUNOLOGY

Direct interaction, instrumental for signaling processes, between LacCer and Lyn in the lipid rafts of neutrophil-like cells

(2014) Elena Chiricozzi et al.   JOURNAL OF LIPID RESEARCH

Of mice and men: how animal models advance our understanding of T-cell function in RA

(2014) Tamás Kobezda et al.   Nature Reviews Rheumatology

Modulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathways

(2014) M E Delgado et al.   Cell Death & Disease

B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk

(2014) Kathrin Kläsener et al.   eLife

Narrative Review: The Role of Th2 Immune Pathway Modulation in the Treatment of Severe Asthma and Its Phenotypes

(2013) Stewart J. Levine   ANNALS OF INTERNAL MEDICINE

GSL-Enriched Membrane Microdomains in Innate Immune Responses

(2013) Hitoshi Nakayama et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

CD1d favors MHC neighborhood, GM1 ganglioside proximity and low detergent sensitive membrane regions on the surface of B lymphocytes

(2013) Dilip Shrestha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Crosstalk between apoptosis, necrosis and autophagy

(2013) Vassiliki Nikoletopoulou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of cell signalling in the crosstalk between autophagy and apoptosis

(2013) Laurence A. Booth et al.   CELLULAR SIGNALLING

Microdomains in the membrane landscape shape antigen-presenting cell function

(2013) Malou Zuidscherwoude et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Anti-neutral glycolipid antibodies in encephalomyeloradiculoneuropathy

(2013) S. Shima et al.   NEUROLOGY

Glycosphingolipids MediatePneumocystisCell Wall β-Glucan Activation of the IL-23/IL-17 Axis in Human Dendritic Cells

(2012) Eva M. Carmona et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Clostridium perfringensAlpha-toxin Recognizes the GM1a-TrkA Complex

(2012) Masataka Oda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ganglioside GM3 Has an Essential Role in the Pathogenesis and Progression of Rheumatoid Arthritis

(2012) Yukinori Tsukuda et al.   PLoS One

CD4 and CD8 T cells require different membrane gangliosides for activation

(2012) M. Nagafuku et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of palmitoylation of Cys415 in helix 8 of the CB1 cannabinoid receptor on membrane localization and signalling

(2011) Sergio Oddi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Streptococcus suis Capsular Polysaccharide Inhibits Phagocytosis through Destabilization of Lipid Microdomains and Prevents Lactosylceramide-Dependent Recognition

(2011) Mathieu Houde et al.   INFECTION AND IMMUNITY

Pathophysiology of asthma: What has our current understanding taught us about new therapeutic approaches?

(2011) Stephen T. Holgate   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lowering Glycosphingolipid Levels in CD4+T Cells Attenuates T Cell Receptor Signaling, Cytokine Production, and Differentiation to the Th17Lineage

(2011) Yunxiang Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Novel Neutrophil Differentiation Marker Phosphatidylglucoside Mediates Neutrophil Apoptosis

(2011) K. Kina et al.   JOURNAL OF IMMUNOLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Overview of asthma; the place of the T cell

(2010) Karim H Shalaby et al.   CURRENT OPINION IN PHARMACOLOGY

Reducing glycosphingolipid biosynthesis in airway cells partially ameliorates disease manifestations in a mouse model of asthma

(2010) J. Karman et al.   INTERNATIONAL IMMUNOLOGY

Increased Expression of Ganglioside GM1 in Peripheral CD4+ T Cells Correlates Soluble Form of CD30 in Systemic Lupus Erythematosus Patients

(2010) Lingli Dong et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

What’s new in asthma pathophysiology and immunopathology?

(2010) Kanami Orihara et al.   Expert Review of Respiratory Medicine

Immunobiology of Asthma

(2009) Qutayba Hamid et al.   Annual Review of Physiology

Segregation of GM1 and GM3 clusters in the cell membrane depends on the intact actin cytoskeleton

(2009) Akikazu Fujita et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling

(2009) Tobias Zech et al.   EMBO JOURNAL

Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth

(2009) N. Ichikawa et al.   JOURNAL OF CELL SCIENCE

Recombinase-deficient T cell development by selective accumulation of CD3 into lipid rafts

(2008) Denise Ferrera et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lipid rafts and T-lymphocyte function: Implications for autoimmunity

(2008) Panagiotis S. Kabouridis et al.   FEBS LETTERS

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lipoarabinomannan of Mycobacterium: Mannose capping by a multifunctional terminal mannosyltransferase

(2008) D. Kaur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA