SUMOylation by SUMO2 is implicated in the degradation of misfolded ataxin-7 via RNF4 in SCA7 models
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Title
SUMOylation by SUMO2 is implicated in the degradation of misfolded ataxin-7 via RNF4 in SCA7 models
Authors
Keywords
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Journal
Disease Models & Mechanisms
Volume 12, Issue 1, Pages dmm036145
Publisher
The Company of Biologists
Online
2018-12-17
DOI
10.1242/dmm.036145
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Note: Only part of the references are listed.- Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor
- (2017) Xingyue He et al. Nature Chemical Biology
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- (2015) Jason P. Chua et al. JOURNAL OF CLINICAL INVESTIGATION
- Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
- (2015) Changwon Kho et al. Nature Communications
- The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice
- (2014) Sandro Alves et al. ACTA NEUROPATHOLOGICA
- The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases
- (2014) Isabel Saez et al. CURRENT GENOMICS
- SUMO Chain-Induced Dimerization Activates RNF4
- (2014) Alejandro Rojas-Fernandez et al. MOLECULAR CELL
- PML, SUMO, and RNF4: Guardians of Nuclear Protein Quality
- (2014) Anne Gärtner et al. MOLECULAR CELL
- A Cellular System that Degrades Misfolded Proteins and Protects against Neurodegeneration
- (2014) Lili Guo et al. MOLECULAR CELL
- Identification and analysis of endogenous SUMO1 and SUMO2/3 targets in mammalian cells and tissues using monoclonal antibodies
- (2014) Sina V Barysch et al. Nature Protocols
- Interferon controls SUMO availability via the Lin28 and let-7 axis to impede virus replication
- (2014) Umut Sahin et al. Nature Communications
- Sumoylation: A Regulatory Protein Modification in Health and Disease
- (2013) Annette Flotho et al. Annual Review of Biochemistry
- SUMO-targeted ubiquitin ligases
- (2013) Annie M. Sriramachandran et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Interferon beta induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice
- (2013) Alice Chort et al. BRAIN
- Trafficking of the Transcription Factor Nrf2 to Promyelocytic Leukemia-Nuclear Bodies
- (2013) Melanie Theodore Malloy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Detecting endogenous SUMO targets in mammalian cells and tissues
- (2013) Janina Becker et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation
- (2013) Jacqueline Gire O’Rourke et al. Cell Reports
- SUMO-1 is Associated with a Subset of Lysosomes in Glial Protein Aggregate Diseases
- (2012) Mathew B. Wong et al. NEUROTOXICITY RESEARCH
- Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model
- (2011) Yi Chun Chen et al. HUMAN MOLECULAR GENETICS
- SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7
- (2009) Alexandre Janer et al. HUMAN MOLECULAR GENETICS
- IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome
- (2009) Leslie Michels Thompson et al. JOURNAL OF CELL BIOLOGY
- Selection of Reference Genes for Quantitative Real-time RT-PCR Studies in Mouse Brain
- (2008) Enrica Boda et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- The Ubiquitin-Proteasome System Is a Key Component of the SUMO-2/3 Cycle
- (2008) Joost Schimmel et al. MOLECULAR & CELLULAR PROTEOMICS
- The Fast-Growing Business of SUMO Chains
- (2008) Helle D. Ulrich MOLECULAR CELL
- RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
- (2008) Michael H. Tatham et al. NATURE CELL BIOLOGY
- Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway
- (2008) Valérie Lallemand-Breitenbach et al. NATURE CELL BIOLOGY
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