DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway

IFN-α induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells

(2018) Alexandra Coomans de Brachène et al.   DIABETOLOGIA

Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis

(2017) Reinaldo S Dos Santos et al.   ENDOCRINOLOGY

Type 1 diabetes mellitus caused by treatment with low-dose interferon-α in a melanoma patient

(2017) Daniel Sossau et al.   MELANOMA RESEARCH

Influenza A virus-induced downregulation of miR-26a contributes to reduced IFNα/β production

(2017) Shijuan Gao et al.   VIROLOGICA SINICA

The diversification of the basic leucine zipper family in eukaryotes correlates with the evolution of multicellularity

(2016) Katia Jindrich et al.   BMC EVOLUTIONARY BIOLOGY

Genetic risk factors for type 1 diabetes

(2016) Flemming Pociot et al.   LANCET

Viral infections in type 1 diabetes mellitus — why the β cells?

(2016) Anne Op de Beeck et al.   Nature Reviews Endocrinology

eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes

(2015) X. Li et al.   ALLERGY

TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells

(2015) Laura Marroqui et al.   DIABETES

Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells

(2015) Laura Marroqui et al.   eLife

Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes

(2015) Laura Marroqui et al.   EBioMedicine

The Diabetes Susceptibility Gene Clec16a Regulates Mitophagy

(2014) Scott A. Soleimanpour et al.   CELL

Fine Mapping and Functional Studies of Risk Variants for Type 1 Diabetes at Chromosome 16p13.13

(2014) M. J. Tomlinson et al.   DIABETES

Candidate genes for type 1 diabetes modulate pancreatic islet inflammation andβ-cell apoptosis

(2013) I. Santin et al.   DIABETES OBESITY & METABOLISM

Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse

(2013) Javier A. Carrero et al.   PLoS One

Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus

(2012) I S Leikfoss et al.   GENES AND IMMUNITY

Case of Type 1 Diabetes Mellitus Following Interferon ^|^beta;-1a Treatment for Multiple Sclerosis

(2012) Taeko Uonaga et al.   INTERNAL MEDICINE

USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis

(2012) I Santin et al.   Cell Death & Disease

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

(2012) Décio L. Eizirik et al.   PLoS Genetics

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic  -Cell Apoptosis via Regulation of the BH3-Only Protein Bim

(2011) I. Santin et al.   DIABETES

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA–CLEC16A–SOCS1 gene complex

(2011) Rebecca L. Zuvich et al.   HUMAN MOLECULAR GENETICS

Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene

(2011) Lucy J. Davison et al.   HUMAN MOLECULAR GENETICS

Identification of a potent epigenetic biomarker for resistance to camptothecin and poor outcome to irinotecan-based chemotherapy in colon cancer

(2011) Koichi Suzuki   INTERNATIONAL JOURNAL OF ONCOLOGY

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

(2011) Philippe Ravassard et al.   JOURNAL OF CLINICAL INVESTIGATION

Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance

(2011) Maikel L. Colli et al.   PLoS Pathogens

STAT1 Is a Master Regulator of Pancreatic β-Cell Apoptosis and Islet Inflammation

(2010) Fabrice Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon- -Induced Pancreatic  -Cell Apoptosis

(2009) F. Moore et al.   DIABETES

MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA

(2009) Maikel L. Colli et al.   HUMAN MOLECULAR GENETICS

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology