Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance

Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction

(2011) Esteban N. Gurzov et al.   TRENDS IN CELL BIOLOGY

Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

(2010) F Allagnat et al.   CELL DEATH AND DIFFERENTIATION

Displacement of Bim by Bmf and Puma rather than increase in Bim level mediates paclitaxel-induced apoptosis in breast cancer cells

(2010) O Kutuk et al.   CELL DEATH AND DIFFERENTIATION

Virus Infections and Type 1 Diabetes Risk

(2010) Merja Roivainen et al.   Current Diabetes Reports

Phagocytosis of Enterovirus-Infected Pancreatic  -Cells Triggers Innate Immune Responses in Human Dendritic Cells

(2010) B. M. Schulte et al.   DIABETES

Mcl-1; the molecular regulation of protein function

(2010) Luke W. Thomas et al.   FEBS LETTERS

p53 Up-regulated Modulator of Apoptosis (PUMA) Activation Contributes to Pancreatic β-Cell Apoptosis Induced by Proinflammatory Cytokines and Endoplasmic Reticulum Stress

(2010) Esteban N. Gurzov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAT1 Is a Master Regulator of Pancreatic β-Cell Apoptosis and Islet Inflammation

(2010) Fabrice Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of Apoptosis of Memory T Cells and Dendritic Cells during the Early Stages of Viral Infection or Exposure to Toll-Like Receptor Agonists

(2010) K. Bahl et al.   JOURNAL OF VIROLOGY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Estimating the Cost of Type 1 Diabetes in the U.S.: A Propensity Score Matching Method

(2010) Betty Tao et al.   PLoS One

Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis

(2009) E N Gurzov et al.   CELL DEATH AND DIFFERENTIATION

Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax

(2009) M. D. McKenzie et al.   DIABETES

Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in  -Cells

(2009) L. G. Grunnet et al.   DIABETES

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon- -Induced Pancreatic  -Cell Apoptosis

(2009) F. Moore et al.   DIABETES

Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB

(2009) Daniel A. Cunha et al.   DIABETES

MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA

(2009) Maikel L. Colli et al.   HUMAN MOLECULAR GENETICS

Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study

(2009) Christopher C Patterson et al.   LANCET

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Apoptosis in animal models of virus-induced disease

(2009) Penny Clarke et al.   NATURE REVIEWS MICROBIOLOGY

Genetics of Type 1A Diabetes

(2009) Patrick Concannon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Double-Stranded RNA Induces Pancreatic  -Cell Apoptosis by Activation of the Toll-Like Receptor 3 and Interferon Regulatory Factor 3 Pathways

(2008) Z. Dogusan et al.   DIABETES

The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

(2008) Décio L. Eizirik et al.   ENDOCRINE REVIEWS

Initiation and execution of lipotoxic ER stress in pancreatic  -cells

(2008) D. A. Cunha et al.   JOURNAL OF CELL SCIENCE

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

BAX activation is initiated at a novel interaction site

(2008) Evripidis Gavathiotis et al.   NATURE