MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA

Pathogen recognition in the innate immune response

(2009) Himanshu Kumar et al.   BIOCHEMICAL JOURNAL

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon- -Induced Pancreatic  -Cell Apoptosis

(2009) F. Moore et al.   DIABETES

The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes

(2009) S. J. Richardson et al.   DIABETOLOGIA

Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes

(2009) Johanna Lempainen et al.   JOURNAL OF AUTOIMMUNITY

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Genetics of Type 1A Diabetes

(2009) Patrick Concannon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomewide Association Studies and Human Disease

(2009) John Hardy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

Increased Expression of CCL2 in Insulin-Producing Cells of Transgenic Mice Promotes Mobilization of Myeloid Cells From the Bone Marrow, Marked Insulitis, and Diabetes

(2008) A. P. Martin et al.   DIABETES

Double-Stranded RNA Induces Pancreatic  -Cell Apoptosis by Activation of the Toll-Like Receptor 3 and Interferon Regulatory Factor 3 Pathways

(2008) Z. Dogusan et al.   DIABETES

Viral Trigger for Type 1 Diabetes: Pros and Cons

(2008) C. M. Filippi et al.   DIABETES

Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5

(2008) Joari De Miranda et al.   FASEB JOURNAL

Type 1 diabetes: Lessons for other autoimmune diseases?

(2008) Leonard C. Harrison et al.   JOURNAL OF AUTOIMMUNITY

Initiation and execution of lipotoxic ER stress in pancreatic  -cells

(2008) D. A. Cunha et al.   JOURNAL OF CELL SCIENCE

A calculated response: control of inflammation by the innate immune system

(2008) Gregory M. Barton   JOURNAL OF CLINICAL INVESTIGATION

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

(2008) Jason D Cooper et al.   NATURE GENETICS

JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

(2008) Esteban N. Gurzov et al.   PLoS One

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY