Antimicrobial macromolecules: synthesis methods and future applications

Antibacterial Activity of Graphite, Graphite Oxide, Graphene Oxide, and Reduced Graphene Oxide: Membrane and Oxidative Stress

(2011) Shaobin Liu et al.   ACS Nano

Antibacterial Mechanism of Action of Arylamide Foldamers

(2011) Bruk Mensa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Improvement of the Efficacy of Linear Undecapeptides against Plant-Pathogenic Bacteria by Incorporation of d-Amino Acids

(2011) Imma Güell et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Influence of C-Terminal Amidation on the Efficacy of Modelin-5

(2011) Sarah R. Dennison et al.   BIOCHEMISTRY

Optimal Oxidative Folding of the Novel Antimicrobial Cyclotide fromHedyotis bifloraRequires High Alcohol Concentrations

(2011) Clarence T. T. Wong et al.   BIOCHEMISTRY

Highly Effective, Water-Soluble, Hemocompatible 1,3-Propylene Oxide-Based Antimicrobials: Poly[(3,3-quaternary/PEG)-copolyoxetanes]

(2011) Souvik Chakrabarty et al.   BIOMACROMOLECULES

Block versus Random Amphiphilic Copolymers as Antibacterial Agents

(2011) Yukari Oda et al.   BIOMACROMOLECULES

A photopolymerized antimicrobial hydrogel coating derived from epsilon-poly-l-lysine

(2011) Chuncai Zhou et al.   BIOMATERIALS

Self-cleaving fusion tags for recombinant protein production

(2011) Yifeng Li   BIOTECHNOLOGY LETTERS

Road to clinical efficacy: challenges and novel strategies for antimicrobial peptide development

(2011) Randal Eckert   Future Microbiology

Discovery and Characterization of Novel Cyclotides Originated from Chimeric Precursors Consisting of Albumin-1 Chain a and Cyclotide Domains in the Fabaceae Family

(2011) Giang Kien Truc Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A chromatography-focused bioprocess that eliminates soluble aggregation for bioactive production of a new antimicrobial peptide candidate

(2011) Xiang Li et al.   JOURNAL OF CHROMATOGRAPHY A

Covalent immobilization of nisin on multi-walled carbon nanotubes: superior antimicrobial and anti-biofilm properties

(2011) Xiaobao Qi et al.   Nanoscale

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1

(2011) Bjoern O. Schroeder et al.   NATURE

Biodegradable nanostructures with selective lysis of microbial membranes

(2011) Fredrik Nederberg et al.   Nature Chemistry

Cell selectivity, mechanism of action and LPS-neutralizing activity of bovine myeloid antimicrobial peptide-18 (BMAP-18) and its analogs

(2011) Eun Kyu Lee et al.   PEPTIDES

Improved proteolytic stability of chicken cathelicidin-2 derived peptides by d-amino acid substitutions and cyclization

(2011) E. Margo Molhoek et al.   PEPTIDES

Chitosan—A versatile semi-synthetic polymer in biomedical applications

(2011) M. Dash et al.   PROGRESS IN POLYMER SCIENCE

Production of recombinant peptides as fusions with SUMO

(2011) Makkapati Satakarni et al.   PROTEIN EXPRESSION AND PURIFICATION

Antimicrobial Behavior of Semifluorinated-Quaternized Triblock Copolymers against Airborne and Marine Microorganisms

(2010) Daewon Park et al.   ACS Applied Materials & Interfaces

Graphene-Based Antibacterial Paper

(2010) Wenbing Hu et al.   ACS Nano

Toxicity of Graphene and Graphene Oxide Nanowalls Against Bacteria

(2010) Omid Akhavan et al.   ACS Nano

The structural parameters for antimicrobial activity, human epithelial cell cytotoxicity and killing mechanism of synthetic monomer and dimer analogues derived from hBD3 C-terminal region

(2010) L. Zhou et al.   AMINO ACIDS

Construction and expression of rabbit neutrophil peptide-1 gene in Escherichia coli

(2010) Yu Ling Sun et al.   ANNALS OF MICROBIOLOGY

Human β-Defensin 2 and β-Defensin 3 Chimeric Peptides Reveal the Structural Basis of the Pathogen Specificity of Their Parent Molecules

(2010) Sascha Jung et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Peptide Fragments of a  -Defensin Derivative with Potent Bactericidal Activity

(2010) N. L. Reynolds et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Systematic Approach to Optimizing Specifically Targeted Antimicrobial Peptides against Streptococcus mutans

(2010) J. He et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Synthetic, Salt-Resistant Analogs of Human Beta-Defensins 1 and 3 Endowed with Enhanced Antimicrobial Activity

(2010) O. Scudiero et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structural determinants of antimicrobial activity in polymers which mimic host defense peptides

(2010) Edmund F. Palermo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Structure−Activity Relationships of Antibacterial and Biocompatible Copolymers

(2010) Thomas R. Stratton et al.   BIOMACROMOLECULES

Effect of Steric Hindrance on the Properties of Antibacterial and Biocompatible Copolymers

(2010) Thomas R. Stratton et al.   BIOMACROMOLECULES

The efficacy of self-assembled cationic antimicrobial peptide nanoparticles against Cryptococcus neoformans for the treatment of meningitis

(2010) Huaying Wang et al.   BIOMATERIALS

Novel gratisin derivatives with high antimicrobial activity and low hemolytic activity

(2010) Makoto Tamaki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Tethering antimicrobial peptides: Current status and potential challenges

(2010) Sagheer A. Onaizi et al.   BIOTECHNOLOGY ADVANCES

A new bioproduction route for a novel antimicrobial peptide

(2010) Derrick Kok Sing Tay et al.   BIOTECHNOLOGY AND BIOENGINEERING

De novo Designed Lipopolysaccharide Binding Peptides: Structure Based Development of Antiendotoxic and Antimicrobial Drugs

(2010) S. Bhattacharjya   CURRENT MEDICINAL CHEMISTRY

Optimization and High-Throughput Screening of Antimicrobial Peptides

(2010) Sylvie E. Blondelle et al.   CURRENT PHARMACEUTICAL DESIGN

Host defense peptides and their antimicrobial-immunomodulatory duality

(2010) Lars Steinstraesser et al.   IMMUNOBIOLOGY

Multivalent Antimicrobial Peptides as Therapeutics: Design Principles and Structural Diversities

(2010) S. P. Liu et al.   International Journal of Peptide Research and Therapeutics

Role of Cationic Group Structure in Membrane Binding and Disruption by Amphiphilic Copolymers

(2010) Edmund F. Palermo et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A polycationic antimicrobial and biocompatible hydrogel with microbe membrane suctioning ability

(2010) Peng Li et al.   NATURE MATERIALS

Intein-Mediated Expression and Purification of an Analog of Glucagon-like Peptide-1 in Escherichia coli

(2010) Chen Ma et al.   PROTEIN AND PEPTIDE LETTERS

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

(2010) N. Srinivas et al.   SCIENCE

De Novo Design of Antimicrobial Polymers, Foldamers, and Small Molecules: From Discovery to Practical Applications

(2009) Gregory N. Tew et al.   ACCOUNTS OF CHEMICAL RESEARCH

Sharper and Faster “Nano Darts” Kill More Bacteria: A Study of Antibacterial Activity of Individually Dispersed Pristine Single-Walled Carbon Nanotube

(2009) Shaobin Liu et al.   ACS Nano

Consequences of Isostructural Main-Chain Modifications for the Design of Antimicrobial Foldamers: Helical Mimics of Host-Defense Peptides Based on a Heterogeneous Amide/Urea Backbone

(2009) Paul Claudon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Role of acetylation and charge in antimicrobial peptides based on human β-defensin-3

(2009) EMILIOS ANDREW PAPANASTASIOU et al.   APMIS

Soluble fusion expression and characterization of bioactive human beta-defensin 26 and 27

(2009) Lei Huang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Structure-Dependent Charge Density as a Determinant of Antimicrobial Activity of Peptide Analogues of Defensin

(2009) Yang Bai et al.   BIOCHEMISTRY

Structure, Dynamics, and Activity of an All-Cysteine Mutated Human β Defensin-3 Peptide Analogue

(2009) Karthik Balakrishna Chandrababu et al.   BIOCHEMISTRY

Micelle-bound structures and dynamics of the hinge deleted analog of melittin and its diastereomer: Implications in cell selective lysis by d-amino acid containing antimicrobial peptides

(2009) Rathi Saravanan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

In Vitro Biocompatibility Studies of Antibacterial Quaternary Polymers

(2009) Thomas R. Stratton et al.   BIOMACROMOLECULES

Chemical Structure of Cationic Groups in Amphiphilic Polymethacrylates Modulates the Antimicrobial and Hemolytic Activities

(2009) Edmund F. Palermo et al.   BIOMACROMOLECULES

Hydrophilic Modifications of an Amphiphilic Polynorbornene and the Effects on its Hemolytic and Antibacterial Activity

(2009) Semra Colak et al.   BIOMACROMOLECULES

Structural Determinants of Antimicrobial Activity and Biocompatibility in Membrane-Disrupting Methacrylamide Random Copolymers

(2009) Edmund F. Palermo et al.   BIOMACROMOLECULES

Incorporation of antimicrobial compounds in mesoporous silica film monolith

(2009) Isabel Izquierdo-Barba et al.   BIOMATERIALS

Injectable in situ cross-linking hydrogels for local antifungal therapy

(2009) Sarah P. Hudson et al.   BIOMATERIALS

Design, syntheses and evaluation of hemocompatible pegylated-antimicrobial polymers with well-controlled molecular structures

(2009) Shrinivas Venkataraman et al.   BIOMATERIALS

Controlling the release of peptide antimicrobial agents from surfaces

(2009) Anita Shukla et al.   BIOMATERIALS

The Hydrophobicity in a Chemically Modified Side-Chain of Cysteine Residues of Thanatin Is Related to Antimicrobial Activity againstMicrococcus luteus

(2009) Yoshitake ORIKASA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Carrier proteins for fusion expression of antimicrobial peptides inEscherichia coli

(2009) Yifeng Li   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Design and Characterization of an Acid-Activated Antimicrobial Peptide

(2009) Lina Li et al.   Chemical Biology & Drug Design

Screening and Characterization of Surface-Tethered Cationic Peptides for Antimicrobial Activity

(2009) Kai Hilpert et al.   CHEMISTRY & BIOLOGY

Synthetic Mimics of Antimicrobial Peptides-A Versatile Ring-Opening Metathesis Polymerization Based Platform for the Synthesis of Selective Antibacterial and Cell-Penetrating Polymers

(2009) Karen Lienkamp et al.   CHEMISTRY-A EUROPEAN JOURNAL

Antimicrobial Polymers Prepared by Ring-Opening Metathesis Polymerization: Manipulating Antimicrobial Properties by Organic Counterion and Charge Density Variation

(2009) Karen Lienkamp et al.   CHEMISTRY-A EUROPEAN JOURNAL

“Doubly Selective” Antimicrobial Polymers: How Do They Differentiate between Bacteria?

(2009) Karen Lienkamp et al.   CHEMISTRY-A EUROPEAN JOURNAL

Expression and Purification of an Antimicrobial Peptide, Bovine Lactoferricin Derivative LfcinB-W10 in Escherichia coli

(2009) Xingjun Feng et al.   CURRENT MICROBIOLOGY

Structure-activity analysis of histatin, a potent wound healing peptide from human saliva: cyclization of histatin potentiates molar activity 1000-fold

(2009) Menno J. Oudhoff et al.   FASEB JOURNAL

Design and activity of a ‘dual-targeted’ antimicrobial peptide

(2009) Jian He et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Structure−activity Relationships among Random Nylon-3 Copolymers That Mimic Antibacterial Host-Defense Peptides

(2009) Brendan P. Mowery et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The effect of C-terminal amidation on the efficacy and selectivity of antimicrobial and anticancer peptides

(2009) Sarah Rachel Dennison et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Leishmanicidal Activity and Immobilization of dermaseptin 01 antimicrobial peptides in ultrathin films for nanomedicine applications

(2009) Maysa F. Zampa et al.   Nanomedicine-Nanotechnology Biology and Medicine

Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent

(2009) Lihong Liu et al.   Nature Nanotechnology

De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers

(2009) S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Foldamers with Heterogeneous Backbones

(2008) W. Seth Horne et al.   ACCOUNTS OF CHEMICAL RESEARCH

Antimicrobial Surfaces through Natural Product Hybrids

(2008) Jean-Yves Wach et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antibacterial and Hemolytic Activities of Pyridinium Polymers as a Function of the Spatial Relationship between the Positive Charge and the Pendant Alkyl Tail

(2008) Varun Sambhy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Immobilization Reduces the Activity of Surface-Bound Cationic Antimicrobial Peptides with No Influence upon the Activity Spectrum

(2008) M. Bagheri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Insights into the Mode of Action of Chitosan as an Antibacterial Compound

(2008) D. Raafat et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antimicrobial Lipopolypeptides Composed of Palmitoyl Di- and Tricationic Peptides:In Vitroandin VivoActivities, Self-Assembly to Nanostructures, and a Plausible Mode of Action†

(2008) Arik Makovitzki et al.   BIOCHEMISTRY

Antimicrobial peptide mimics for improved therapeutic properties

(2008) Shahar Rotem et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Control of cell selectivity of antimicrobial peptides

(2008) Katsumi Matsuzaki   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Bactericidal activity of LFchimera is stronger and less sensitive to ionic strength than its constituent lactoferricin and lactoferrampin peptides

(2008) J BOLSCHER et al.   BIOCHIMIE

Investigating the Effect of Increasing Charge Density on the Hemolytic Activity of Synthetic Antimicrobial Polymers

(2008) Zoha M. AL-Badri et al.   BIOMACROMOLECULES

Hydrogel based on interpenetrating polymer networks of dextran and gelatin for vascular tissue engineering

(2008) Yunxiao Liu et al.   BIOMATERIALS

Synthetic mimics of antimicrobial peptides

(2008) Abhigyan Som et al.   BIOPOLYMERS

Membrane interactions of designed cationic antimicrobial peptides: The two thresholds

(2008) Evgenia Glukhov et al.   BIOPOLYMERS

Microbial bio-production of a recombinant stimuli-responsive biosurfactant

(2008) W. Kaar et al.   BIOTECHNOLOGY AND BIOENGINEERING

Antibacterial Activity of Short Peptides Based on Pleurocidin and Their Interaction with Phospholipid Membranes

(2008) Nobuaki Tsuda et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Linear Analogues of Human β-Defensin 3: Concepts for Design of Antimicrobial Peptides with Reduced Cytotoxicity to Mammalian Cells

(2008) Shouping Liu et al.   CHEMBIOCHEM

The Role of Hydrophobicity in the Antimicrobial and Hemolytic Activities of Polymethacrylate Derivatives

(2008) Kenichi Kuroda et al.   CHEMISTRY-A EUROPEAN JOURNAL

Comparison of Facially Amphiphilic versus Segregated Monomers in the Design of Antibacterial Copolymers

(2008) Gregory J. Gabriel et al.   CHEMISTRY-A EUROPEAN JOURNAL

De novo designed synthetic mimics of antimicrobial peptides

(2008) Richard W Scott et al.   CURRENT OPINION IN BIOTECHNOLOGY

Analysis and Separation of Residues Important for the Chemoattractant and Antimicrobial Activities of β-Defensin 3

(2008) Karen Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Template-induced directional growth of ZnO nanomeshes by colloidal crystals

(2008) Ming Fu et al.   JOURNAL OF MATERIALS CHEMISTRY

Dual Mechanism of Bacterial Lethality for a Cationic Sequence-Random Copolymer that Mimics Host-Defense Antimicrobial Peptides

(2008) Raquel F. Epand et al.   JOURNAL OF MOLECULAR BIOLOGY

Influence of Lipid Composition on Membrane Activity of Antimicrobial Phenylene Ethynylene Oligomers

(2008) Abhigyan Som et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Antimicrobial Polymers Prepared by ROMP with Unprecedented Selectivity: A Molecular Construction Kit Approach

(2008) Karen Lienkamp et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and characterization of amphiphilic o-phenylene ethynylene oligomers

(2008) Morris M. Slutsky et al.   NEW JOURNAL OF CHEMISTRY

Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides

(2008) N. P. Chongsiriwatana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of bioactive human beta-defensin 5 and 6 in Escherichia coli by soluble fusion expression

(2008) Lei Huang et al.   PROTEIN EXPRESSION AND PURIFICATION

The Bacteria Fight Back

(2008) G. Taubes   SCIENCE

The Epidemic of Antibiotic-Resistant Infections: A Call to Action for the Medical Community from the Infectious Diseases Society of America

(2007) B. Spellberg et al.   CLINICAL INFECTIOUS DISEASES

Host–pathogen interactions in sepsis

(2007) Tom van der Poll et al.   LANCET INFECTIOUS DISEASES

Conformationally rigid proteomimetics: a case study in designing antimicrobial aryl oligomers

(2007) Gregory J. Gabriel et al.   ORGANIC & BIOMOLECULAR CHEMISTRY