Opportunities and Limitations of Modelling Alzheimer’s Disease with Induced Pluripotent Stem Cells
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Opportunities and Limitations of Modelling Alzheimer’s Disease with Induced Pluripotent Stem Cells
Authors
Keywords
-
Journal
Journal of Clinical Medicine
Volume 3, Issue 4, Pages 1357-1372
Publisher
MDPI AG
Online
2014-12-05
DOI
10.3390/jcm3041357
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons
- (2014) Christina R. Muratore et al. HUMAN MOLECULAR GENETICS
- Stem cell derived basal forebrain cholinergic neurons from Alzheimer’s disease patients are more susceptible to cell death
- (2014) Lishu Duan et al. Molecular Neurodegeneration
- Abnormalities in human pluripotent cells due to reprogramming mechanisms
- (2014) Hong Ma et al. NATURE
- A three-dimensional human neural cell culture model of Alzheimer’s disease
- (2014) Se Hoon Choi et al. NATURE
- The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease
- (2014) Tara L. Spires-Jones et al. NEURON
- Selection Via Pluripotency-Related Transcriptional Screen Minimizes the Influence of Somatic Origin on iPSC Differentiation Propensity
- (2014) Katherine A. Hartjes et al. STEM CELLS
- Genomic Editing Tools to Model Human Diseases with Isogenic Pluripotent Stem Cells
- (2014) Huen Suk Kim et al. STEM CELLS AND DEVELOPMENT
- iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis
- (2014) David C. Schöndorf et al. Nature Communications
- Role of astroglia in Down’s syndrome revealed by patient-derived human-induced pluripotent stem cells
- (2014) Chen Chen et al. Nature Communications
- Effect of Potent γ-Secretase Modulator in Human Neurons Derived From Multiple Presenilin 1–Induced Pluripotent Stem Cell Mutant Carriers
- (2014) Qing Liu et al. JAMA Neurology
- Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription
- (2013) Scott D. Ryan et al. CELL
- Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
- (2013) Justine D. Miller et al. Cell Stem Cell
- Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
- (2013) Peter Reinhardt et al. Cell Stem Cell
- Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness
- (2013) Takayuki Kondo et al. Cell Stem Cell
- A Cut above the Rest: Targeted Genome Editing Technologies in Human Pluripotent Stem Cells
- (2013) Mo Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing
- (2013) G Barry et al. MOLECULAR PSYCHIATRY
- Translating dosage compensation to trisomy 21
- (2013) Jun Jiang et al. NATURE
- Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β
- (2013) Elsa Suberbielle et al. NATURE NEUROSCIENCE
- Alzheimer disease therapy—moving from amyloid-β to tau
- (2013) Ezio Giacobini et al. Nature Reviews Neurology
- Review: The genetics of Alzheimer's disease; putting flesh on the bones
- (2013) C. Medway et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Inflammation in Alzheimer Disease--A Brief Review of the Basic Science and Clinical Literature
- (2013) T. Wyss-Coray et al. Cold Spring Harbor Perspectives in Medicine
- The role of DNA damage and repair in aging through the prism of Koch-like criteria
- (2012) Alexey A. Moskalev et al. AGEING RESEARCH REVIEWS
- Presenilin-1 L166P Mutant Human Pluripotent Stem Cell–Derived Neurons Exhibit Partial Loss of γ-Secretase Activity in Endogenous Amyloid-β Generation
- (2012) Philipp Koch et al. AMERICAN JOURNAL OF PATHOLOGY
- Epigenetic Alterations in Human Pluripotent Stem Cells: A Tale of Two Cultures
- (2012) Anton Wutz Cell Stem Cell
- Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives
- (2012) Kristopher L. Nazor et al. Cell Stem Cell
- Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling
- (2012) Shila Mekhoubad et al. Cell Stem Cell
- Origins of Alzheimerʼs disease
- (2012) Erik S. Musiek et al. CURRENT OPINION IN NEUROLOGY
- Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
- (2012) Adriana Sánchez-Danés et al. EMBO Molecular Medicine
- Activity-Dependent Human Brain Coding/Noncoding Gene Regulatory Networks
- (2012) L. Lipovich et al. GENETICS
- Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory
- (2012) Katherine R. Martin et al. HUMAN MOLECULAR GENETICS
- Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
- (2012) Mason A. Israel et al. NATURE
- Review: Microglia of the aged brain: primed to be activated and resistant to regulation
- (2012) D. M. Norden et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Residual Expression of Reprogramming Factors Affects the Transcriptional Program and Epigenetic Signatures of Induced Pluripotent Stem Cells
- (2012) Cesar A. Sommer et al. PLoS One
- A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome
- (2012) Y. Shi et al. Science Translational Medicine
- StemCellDB: The Human Pluripotent Stem Cell Database at the National Institutes of Health
- (2012) Barbara S. Mallon et al. Stem Cell Research
- Integration-Free Induced Pluripotent Stem Cells Model Genetic and Neural Developmental Features of Down Syndrome Etiology
- (2012) James A. Briggs et al. STEM CELLS
- Dynamic histone marks in the hippocampus and cortex facilitate memory consolidation
- (2012) Johannes Gräff et al. Nature Communications
- BACE2 Expression Increases in Human Neurodegenerative Disease
- (2011) Christopher J. Holler et al. AMERICAN JOURNAL OF PATHOLOGY
- Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines
- (2011) Christoph Bock et al. CELL
- Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture
- (2011) Louise C. Laurent et al. Cell Stem Cell
- miR-371-3 Expression Predicts Neural Differentiation Propensity in Human Pluripotent Stem Cells
- (2011) Hyesoo Kim et al. Cell Stem Cell
- Modeling familial Alzheimer's disease with induced pluripotent stem cells
- (2011) Takuya Yagi et al. HUMAN MOLECULAR GENETICS
- Regulation of RCAN1 Protein Activity by Dyrk1A Protein-mediated Phosphorylation
- (2011) Min-Su Jung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hippocampal Hyperactivation Associated with Cortical Thinning in Alzheimer's Disease Signature Regions in Non-Demented Elderly Adults
- (2011) D. Putcha et al. JOURNAL OF NEUROSCIENCE
- Modelling schizophrenia using human induced pluripotent stem cells
- (2011) Kristen J. Brennand et al. NATURE
- Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells
- (2011) Luis F. Z. Batista et al. NATURE
- Somatic coding mutations in human induced pluripotent stem cells
- (2011) Athurva Gore et al. NATURE
- Copy number variation and selection during reprogramming to pluripotency
- (2011) Samer M. Hussein et al. NATURE
- Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
- (2011) Ryan Lister et al. NATURE
- Neuronal activity modifies the DNA methylation landscape in the adult brain
- (2011) Junjie U Guo et al. NATURE NEUROSCIENCE
- Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
- (2011) Berislav V. Zlokovic NATURE REVIEWS NEUROSCIENCE
- Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease
- (2011) Naoki Yahata et al. PLoS One
- Hippocampal synaptic plasticity in Alzheimer’s disease: what have we learned so far from transgenic models?
- (2011) Cristina Marchetti et al. REVIEWS IN THE NEUROSCIENCES
- Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges
- (2011) Mason A Israel et al. Genome Medicine
- Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells
- (2010) Matthew G. Guenther et al. Cell Stem Cell
- Depolarization induces downregulation of DNMT1 and DNMT3 in primary cortical cultures
- (2010) Rajiv P. Sharma et al. Epigenetics
- Aging in Mouse Brain Is a Cell/Tissue-Level Phenomenon Exacerbated by Proteasome Loss
- (2010) Lei Mao et al. JOURNAL OF PROTEOME RESEARCH
- L1 retrotransposition in neurons is modulated by MeCP2
- (2010) Alysson R. Muotri et al. NATURE
- Widespread transcription at neuronal activity-regulated enhancers
- (2010) Tae-Kyung Kim et al. NATURE
- Epigenetic memory in induced pluripotent stem cells
- (2010) K. Kim et al. NATURE
- Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
- (2010) Jose M Polo et al. NATURE BIOTECHNOLOGY
- Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
- (2010) Jorge J Palop et al. NATURE NEUROSCIENCE
- Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
- (2010) Jian Feng et al. NATURE NEUROSCIENCE
- Generation of microglial cells from mouse embryonic stem cells
- (2010) Clara Beutner et al. Nature Protocols
- The clinical use of structural MRI in Alzheimer disease
- (2010) Giovanni B. Frisoni et al. Nature Reviews Neurology
- Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease
- (2010) Lars M. Ittner et al. NATURE REVIEWS NEUROSCIENCE
- Reactive astrocytes give neurons less support: implications for Alzheimer's disease
- (2010) Megan L. Steele et al. NEUROBIOLOGY OF AGING
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Microglial precursors derived from mouse embryonic stem cells
- (2009) Isabella Napoli et al. GLIA
- BACE1 and BACE2 enzymatic activities in Alzheimer’s disease
- (2009) Rachel R. Ahmed et al. JOURNAL OF NEUROCHEMISTRY
- Identification of independent APP locus duplication in Japanese patients with early-onset Alzheimer disease
- (2009) K Kasuga et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming
- (2009) Jie Deng et al. NATURE BIOTECHNOLOGY
- Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
- (2009) Akiko Doi et al. NATURE GENETICS
- Transcriptional Signature and Memory Retention of Human-Induced Pluripotent Stem Cells
- (2009) Maria C. N. Marchetto et al. PLoS One
- Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing
- (2009) I. E. Schor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies
- (2009) J. O. Korbel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
- (2009) J. Yu et al. SCIENCE
- Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells
- (2008) Maria C.N. Marchetto et al. Cell Stem Cell
- Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome
- (2008) Fei Liu et al. FASEB JOURNAL
- X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations
- (2008) Y. Shen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer’s disease
- (2007) Soo-Ryoon Ryoo et al. JOURNAL OF NEUROCHEMISTRY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now