iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis
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Title
iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis
Authors
Keywords
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Journal
Nature Communications
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-06-06
DOI
10.1038/ncomms5028
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Note: Only part of the references are listed.- Loss of Function of Glucocerebrosidase GBA2 Is Responsible for Motor Neuron Defects in Hereditary Spastic Paraplegia
- (2013) Elodie Martin et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Mutations in GBA2 Cause Autosomal-Recessive Cerebellar Ataxia with Spasticity
- (2013) Monia B. Hammer et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Mass Spectrometry Based Method to Increase Throughput for Kinome Analyses Using ATP Probes
- (2013) F. E. McAllister et al. ANALYTICAL CHEMISTRY
- Calcium dysregulation in Parkinson’s disease
- (2013) Anthony H.V. Schapira BRAIN
- Parkinson’s disease is associated with altered expression of CaV1 channels and calcium-binding proteins
- (2013) Michael J. Hurley et al. BRAIN
- Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease
- (2013) Laura D. Osellame et al. Cell Metabolism
- Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
- (2013) Peter Reinhardt et al. Cell Stem Cell
- Rotenone induces neurotoxicity through Rac1-dependent activation of NADPH oxidase in SHSY-5Y cells
- (2013) Rituraj Pal et al. FEBS LETTERS
- Unfolded protein response in Gaucher disease: from human to Drosophila
- (2013) Gali Maor et al. Orphanet Journal of Rare Diseases
- Combined Flow Cytometric Analysis of Surface and Intracellular Antigens Reveals Surface Molecule Markers of Human Neuropoiesis
- (2013) Gizem Turaç et al. PLoS One
- A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies
- (2013) Michael A. Nalls et al. JAMA Neurology
- Increasing the Multiplexing Capacity of TMTs Using Reporter Ion Isotopologues with Isobaric Masses
- (2012) Graeme C. McAlister et al. ANALYTICAL CHEMISTRY
- Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains
- (2012) Matthew E. Gegg et al. ANNALS OF NEUROLOGY
- The Non-lysosomal β-Glucosidase GBA2 Is a Non-integral Membrane-associated Protein at the Endoplasmic Reticulum (ER) and Golgi
- (2012) Heinz G. Körschen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of embryonic stem cell–derived midbrain dopaminergic neurons for engraftment
- (2012) Yosif M. Ganat et al. JOURNAL OF CLINICAL INVESTIGATION
- Cell surface associated glycohydrolases in normal and Gaucher disease fibroblasts
- (2012) Massimo Aureli et al. JOURNAL OF INHERITED METABOLIC DISEASE
- MutantGBA1Expression and Synucleinopathy Risk: First Insights from Cellular and Mouse Models
- (2012) S. Pablo Sardi et al. Neurodegenerative Diseases
- The Proteomics Identifications (PRIDE) database and associated tools: status in 2013
- (2012) Juan Antonio Vizcaíno et al. NUCLEIC ACIDS RESEARCH
- Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease
- (2012) L. M. Panicker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
- (2012) O. Cooper et al. Science Translational Medicine
- Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies
- (2011) Joseph R. Mazzulli et al. CELL
- Accumulation and distribution of α-synuclein and ubiquitin in the CNS of Gaucher disease mouse models
- (2011) Y.H. Xu et al. MOLECULAR GENETICS AND METABOLISM
- Lysosomal storage disorders and Parkinson's disease: Gaucher disease and beyond
- (2011) Tamar Shachar et al. MOVEMENT DISORDERS
- MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics
- (2011) Lily Ting et al. NATURE METHODS
- GBA-associated PD presents with nonmotor characteristics
- (2011) K. Brockmann et al. NEUROLOGY
- Cell-Surface Marker Signatures for the Isolation of Neural Stem Cells, Glia and Neurons Derived from Human Pluripotent Stem Cells
- (2011) Shauna H. Yuan et al. PLoS One
- CNS expression of glucocerebrosidase corrects -synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy
- (2011) S. P. Sardi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of Histocompatible Primate-Induced Pluripotent Stem Cells for Neural Transplantation
- (2011) Michela Deleidi et al. STEM CELLS
- Exploring the link between glucocerebrosidase mutations and parkinsonism
- (2011) Wendy Westbroek et al. TRENDS IN MOLECULAR MEDICINE
- Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders
- (2010) Ozlem Goker-Alpan et al. ACTA NEUROPATHOLOGICA
- A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression
- (2010) Edward L. Huttlin et al. CELL
- The Role of Glucocerebrosidase Mutations in Parkinson Disease and Lewy Body Disorders
- (2010) Arash Velayati et al. Current Neurology and Neuroscience Reports
- Altered lipid content inhibits autophagic vesicular fusion
- (2010) Hiroshi Koga et al. FASEB JOURNAL
- The risk of Parkinson’s disease in type 1 Gaucher disease
- (2010) Gilberto Bultron et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Acute action of rotenone on nigral dopaminergic neurons - involvement of reactive oxygen species and disruption of Ca2+homeostasis
- (2009) Peter S. Freestone et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Endogenous Calcium Buffering Capacity of Substantia Nigral Dopamine Neurons
- (2009) R. C. Foehring et al. JOURNAL OF NEUROPHYSIOLOGY
- Robust Pacemaking in Substantia Nigra Dopaminergic Neurons
- (2009) J. N. Guzman et al. JOURNAL OF NEUROSCIENCE
- Cerebrospinal fluid β-glucocerebrosidase activity is reduced in Dementia with Lewy Bodies
- (2009) L. Parnetti et al. NEUROBIOLOGY OF DISEASE
- Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: A biological link between Gaucher disease and parkinsonism
- (2009) Amy B. Manning-Boğ et al. NEUROTOXICOLOGY
- Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease
- (2009) E. Sidransky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Disease-Specific Induced Pluripotent Stem Cells
- (2008) In-Hyun Park et al. CELL
- Lipid content of brain, brain membrane lipid domains, and neurons from acid sphingomyelinase deficient mice
- (2008) Federica Scandroglio et al. JOURNAL OF NEUROCHEMISTRY
- Genetic variability in the SNCA gene influences α-synuclein levels in the blood and brain
- (2007) Julia Fuchs et al. FASEB JOURNAL
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