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Title
Metabolic Profiles Associated With Metformin Efficacy in Cancer
Authors
Keywords
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Journal
Frontiers in Endocrinology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-08-21
DOI
10.3389/fendo.2018.00372
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Note: Only part of the references are listed.- Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect
- (2018) Philipp F. Secker et al. Cell Death & Disease
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- Metformin monotherapy in melanoma: a pilot, open-label, prospective, and multicentric study indicates no benefit
- (2017) Henri Montaudié et al. Pigment Cell & Melanoma Research
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- (2017) Fanqiang Meng et al. Journal of Diabetes Research
- Metformin synergistic pemetrexed suppresses non-small-cell lung cancer cell proliferation and invasion in vitro
- (2017) Yan Zhang et al. Cancer Medicine
- Metformin intake associates with better cognitive function in patients with Huntington's disease
- (2017) David Hervás et al. PLoS One
- Combining metformin and nelfinavir exhibits synergistic effects against the growth of human cervical cancer cells and xenograft in nude mice
- (2017) Chenglai Xia et al. Scientific Reports
- The effect of metformin on survival of patients with pancreatic cancer: a meta-analysis
- (2017) Xiaogang Li et al. Scientific Reports
- Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer
- (2017) Niki Marie Zacharias et al. Scientific Reports
- Combinational strategies of metformin and chemotherapy in cancers
- (2016) Hui-Hui Zhang et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers
- (2016) Xiaojing Liu et al. Cell Metabolism
- Metformin in pancreatic cancer treatment: from clinical trials through basic research to biomarker quantification
- (2016) Archana Bhaw-Luximon et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Metformin Protects Cells from Mutant Huntingtin Toxicity Through Activation of AMPK and Modulation of Mitochondrial Dynamics
- (2016) Jing Jin et al. NEUROMOLECULAR MEDICINE
- Reduced colorectal cancer incidence in type 2 diabetic patients treated with metformin: a meta-analysis
- (2016) Zhihong Nie et al. PHARMACEUTICAL BIOLOGY
- Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells
- (2016) Mamatha Bhat et al. Oncotarget
- Metformin treatment reduces temozolomide resistance of glioblastoma cells
- (2016) Seung Ho Yang et al. Oncotarget
- The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer
- (2016) Étienne Audet-Walsh et al. Cell Reports
- The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration
- (2016) Linda A. Villani et al. Molecular Metabolism
- Elevated expression of glutaminase confers glucose utilization via glutaminolysis in prostate cancer
- (2015) Tiejun Pan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2015) Hengyi Chen et al. CANCER LETTERS
- Metformin Action: Concentrations Matter
- (2015) Ling He et al. Cell Metabolism
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- (2015) R.-H. Tian et al. Clinical & Translational Oncology
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- (2015) Chao-Cheng Huang et al. Disease Models & Mechanisms
- Xanthohumol induces generation of reactive oxygen species and triggers apoptosis through inhibition of mitochondrial electron transfer chain complex I
- (2015) Bo Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
- (2015) Yan Xiang et al. JOURNAL OF CLINICAL INVESTIGATION
- Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial
- (2015) Sil Kordes et al. LANCET ONCOLOGY
- Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells
- (2015) Camille Loubière et al. Oncotarget
- Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression
- (2015) Balkrishna Chaube et al. Oncotarget
- Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis
- (2015) Takla Griss et al. PLOS BIOLOGY
- Metformin-induced metabolic reprogramming of chemoresistant ALDHbright breast cancer cells
- (2015) Mario Cioce et al. Oncotarget
- Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria
- (2014) Hannah R. Bridges et al. BIOCHEMICAL JOURNAL
- Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy
- (2014) Alba Luengo et al. BMC BIOLOGY
- Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis
- (2014) Akimasa Takahashi et al. Cancer Cell International
- Control of Gluconeogenesis by Metformin: Does Redox Trump Energy Charge?
- (2014) Joseph A. Baur et al. Cell Metabolism
- Metformin: From Mechanisms of Action to Therapies
- (2014) Marc Foretz et al. Cell Metabolism
- Metformin is associated with reduced risk of pancreatic cancer in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
- (2014) Zheng Wang et al. DIABETES RESEARCH AND CLINICAL PRACTICE
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- (2014) Anna Wilk et al. MOLECULAR AND CELLULAR BIOLOGY
- Synergistic Simvastatin and Metformin Combination Chemotherapy for Osseous Metastatic Castration-Resistant Prostate Cancer
- (2014) M. A. Babcook et al. MOLECULAR CANCER THERAPEUTICS
- Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
- (2014) Anila K. Madiraju et al. NATURE
- Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
- (2014) Kıvanç Birsoy et al. NATURE
- Metformin—mode of action and clinical implications for diabetes and cancer
- (2014) Ida Pernicova et al. Nature Reviews Endocrinology
- Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
- (2014) A. Janzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK
- (2014) X. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
- (2014) William W Wheaton et al. eLife
- Metformin Enhances Cisplatin Cytotoxicity by Suppressing Signal Transducer and Activator of Transcription–3 Activity Independently of the Liver Kinase B1–AMP-Activated Protein Kinase Pathway
- (2013) Chien-Chung Lin et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Bioenergetic medicine
- (2013) Russell H Swerdlow BRITISH JOURNAL OF PHARMACOLOGY
- Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism
- (2013) S.-M. Fendt et al. CANCER RESEARCH
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- (2013) Jian Duo et al. DNA AND CELL BIOLOGY
- Metformin reverses multidrug resistance and epithelial–mesenchymal transition (EMT) via activating AMP-activated protein kinase (AMPK) in human breast cancer cells
- (2013) Chen Qu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
- (2013) Russell A. Miller et al. NATURE
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- (2012) Luis E. Raez et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
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- (2012) E. Klimcakova et al. CANCER RESEARCH
- “Double hit” makes the difference
- (2012) Frédéric Bost CELL CYCLE
- Metformin and Prostate Cancer: Reduced Development of Castration-resistant Disease and Prostate Cancer Mortality
- (2012) Daniel E. Spratt et al. EUROPEAN UROLOGY
- Metformin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and modulation of the mTOR pathway
- (2012) Rabbie K. Hanna et al. GYNECOLOGIC ONCOLOGY
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The PGC-1/ERR signaling axis in cancer
- (2012) G Deblois et al. ONCOGENE
- Metformin and reduced risk of hepatocellular carcinoma in diabetic patients: a meta-analysis
- (2012) Hui Zhang et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients
- (2011) X.- X. He et al. ANNALS OF ONCOLOGY
- PGC1 Promotes Tumor Growth by Inducing Gene Expression Programs Supporting Lipogenesis
- (2011) K. Bhalla et al. CANCER RESEARCH
- Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types
- (2011) D. Iliopoulos et al. CANCER RESEARCH
- Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth
- (2011) G. Z. Rocha et al. CLINICAL CANCER RESEARCH
- Cellular and molecular mechanisms of metformin: an overview
- (2011) Benoit Viollet et al. CLINICAL SCIENCE
- Genetic downregulation of AMPK-α isoforms uncovers the mechanism by which metformin decreases FA uptake and oxidation in skeletal muscle cells
- (2010) Lindsey D. Bogachus et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Metformin induces suppression of NAD(P)H oxidase activity in podocytes
- (2010) Agnieszka Piwkowska et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
- (2010) Jian-Bin Wang et al. CANCER CELL
- Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells
- (2010) I. Ben Sahra et al. CANCER RESEARCH
- Diabetes and Cancer: A consensus report
- (2010) E. Giovannucci et al. DIABETES CARE
- Metformin Activates AMP Kinase through Inhibition of AMP Deaminase
- (2010) Jiangyong Ouyang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes
- (2009) Yoshihisa Sogame et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
- (2009) H. A. Hirsch et al. CANCER RESEARCH
- Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia: A nested case-control analysis
- (2008) M. Bodmer et al. DIABETES CARE
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