The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration

Title
The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration
Authors
Keywords
AMP-activated protein kinase AMPK, Lipogenesis, SGLT2, Prostate cancer, Lung cancer, Breast cancer, Colon cancer, mTOR, Cancer metabolism, Glucose uptake
Journal
Molecular Metabolism
Volume 5, Issue 10, Pages 1048-1056
Publisher
Elsevier BV
Online
2016-09-02
DOI
10.1016/j.molmet.2016.08.014

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