Metformin Enhances Cisplatin Cytotoxicity by Suppressing Signal Transducer and Activator of Transcription–3 Activity Independently of the Liver Kinase B1–AMP-Activated Protein Kinase Pathway

Metformin Reduces Endogenous Reactive Oxygen Species and Associated DNA Damage

(2012) C. Algire et al.   Cancer Prevention Research

Prognostic significance of STAT3 expression and its correlation with chemoresistance of non-small cell lung cancer cells

(2011) Zhenjie Yin et al.   ACTA HISTOCHEMICA

Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth

(2011) G. Z. Rocha et al.   CLINICAL CANCER RESEARCH

NF-κB and STAT3 cooperatively induce IL6 in starved cancer cells

(2011) S Yoon et al.   ONCOGENE

Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat vascular smooth muscle cells

(2011) Sukanya Phalitakul et al.   PHARMACOLOGICAL RESEARCH

Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers

(2011) Giang Huong Nguyen et al.   Cancers

STAT3 transcriptional factor activated by reactive oxygen species induces IL6 in starvation-induced autophagy of cancer cells

(2010) Sarah Yoon et al.   Autophagy

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

(2010) Adem Kalender et al.   Cell Metabolism

Metformin: A Therapeutic Opportunity in Breast Cancer

(2010) A. M. Gonzalez-Angulo et al.   CLINICAL CANCER RESEARCH

AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3)

(2010) A. Nerstedt et al.   DIABETOLOGIA

Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans

(2010) Sabine Lagger et al.   EMBO JOURNAL

Metformin: Taking away the candy for cancer?

(2010) Mathilde Jalving et al.   EUROPEAN JOURNAL OF CANCER

Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin

(2010) Tingyan Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Malignant pleural effusion cells show aberrant glucose metabolism gene expression

(2010) C.-C. Lin et al.   EUROPEAN RESPIRATORY JOURNAL

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

(2010) Jianhui Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

(2009) H. A. Hirsch et al.   CANCER RESEARCH

New Users of Metformin Are at Low Risk of Incident Cancer: A cohort study among people with type 2 diabetes

(2009) G. Libby et al.   DIABETES CARE

Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer

(2009) Sao Jiralerspong et al.   JOURNAL OF CLINICAL ONCOLOGY

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

(2009) Morris E Feldman et al.   PLOS BIOLOGY

Utility of metformin in breast cancer treatment, is neoangiogenesis a risk factor?

(2008) Vuk Stambolic et al.   BREAST CANCER RESEARCH AND TREATMENT

Mechanisms of Action of Metformin in Type 2 Diabetes and Associated Complications: An Overview

(2008) Sonia Correia et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

(2008) I Ben Sahra et al.   ONCOGENE

Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by 18F-FDG-microPET or external caliper

(2008) Mette Munk Jensen et al.   BMC MEDICAL IMAGING