Epigenetic control of gene function in schistosomes: a source of therapeutic targets?
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Title
Epigenetic control of gene function in schistosomes: a source of therapeutic targets?
Authors
Keywords
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Journal
Frontiers in Genetics
Volume 5, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-09-10
DOI
10.3389/fgene.2014.00317
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Note: Only part of the references are listed.- Lysine Glutarylation Is a Protein Posttranslational Modification Regulated by SIRT5
- (2014) Minjia Tan et al. Cell Metabolism
- Genomic patterns and context specific interpretation of DNA methylation
- (2014) Tuncay Baubec et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- New and emerging HDAC inhibitors for cancer treatment
- (2014) Alison C. West et al. JOURNAL OF CLINICAL INVESTIGATION
- Molecular Basis for the Antiparasitic Activity of a Mercaptoacetamide Derivative That Inhibits Histone Deacetylase 8 (HDAC8) from the Human Pathogen Schistosoma mansoni
- (2014) Diana A. Stolfa et al. JOURNAL OF MOLECULAR BIOLOGY
- The discovery of first-in-class drugs: origins and evolution
- (2014) Jörg Eder et al. NATURE REVIEWS DRUG DISCOVERY
- Therapeutic targeting of microRNAs: current status and future challenges
- (2014) Zhonghan Li et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting bromodomains: epigenetic readers of lysine acetylation
- (2014) Panagis Filippakopoulos et al. NATURE REVIEWS DRUG DISCOVERY
- Novel expression profiles of microRNAs suggest that specific miRNAs regulate gene expression for the sexual maturation of female Schistosoma japonicum after pairing
- (2014) Jun Sun et al. Parasites & Vectors
- Small molecule SIRT1 activators for the treatment of aging and age-related diseases
- (2014) Basil P. Hubbard et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Epigenetic Changes Modulate Schistosome Egg Formation and Are a Novel Target for Reducing Transmission of Schistosomiasis
- (2014) Vitor Coutinho Carneiro et al. PLoS Pathogens
- Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
- (2013) S. R. Daigle et al. BLOOD
- Cytosine methylation is a conserved epigenetic feature found throughout the phylum Platyhelminthes
- (2013) Kathrin K Geyer et al. BMC GENOMICS
- Laccaic Acid A Is a Direct, DNA-competitive Inhibitor of DNA Methyltransferase 1
- (2013) Rebecca L. Fagan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substantial Loss of Conserved and Gain of Novel MicroRNA Families in Flatworms
- (2013) Bastian Fromm et al. MOLECULAR BIOLOGY AND EVOLUTION
- SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine
- (2013) Hong Jiang et al. NATURE
- Chromatin proteins and modifications as drug targets
- (2013) Kristian Helin et al. NATURE
- Histone lysine demethylases as targets for anticancer therapy
- (2013) Jonas W. Højfeldt et al. NATURE REVIEWS DRUG DISCOVERY
- MicroRNAs and other non-coding RNAs as targets for anticancer drug development
- (2013) Hui Ling et al. NATURE REVIEWS DRUG DISCOVERY
- Emerging roles for chromatin as a signal integration and storage platform
- (2013) Aimee I. Badeaux et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Micromanaging Hepatitis C Virus
- (2013) Judy Lieberman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Treatment of HCV Infection by Targeting MicroRNA
- (2013) Harry L.A. Janssen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Dnmt2-dependent methylomes lack defined DNA methylation patterns
- (2013) G. Raddatz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Schistosoma mansoni Sirtuins: Characterization and Potential as Chemotherapeutic Targets
- (2013) Julien Lancelot et al. PLoS Neglected Tropical Diseases
- Praziquantel Treatment Decreases Schistosoma mansoni Genetic Diversity in Experimental Infections
- (2013) Regina Coeli et al. PLoS Neglected Tropical Diseases
- Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni
- (2013) Martin Marek et al. PLoS Pathogens
- Schistosoma mansoni Mucin Gene (SmPoMuc) Expression: Epigenetic Control to Shape Adaptation to a New Host
- (2013) Cecile Perrin et al. PLoS Pathogens
- Targeting Schistosome Histone Modifying Enzymes for Drug Development
- (2012) R Pierce CURRENT PHARMACEUTICAL DESIGN
- Sirtuin Catalysis and Regulation
- (2012) Jessica L. Feldman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis for Sirtuin Activity and Inhibition
- (2012) Hua Yuan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions
- (2012) David S. Hewings et al. JOURNAL OF MEDICINAL CHEMISTRY
- Schistosoma mansoni histones: From transcription to chromatin regulation; an in silico analysis
- (2012) Letícia Anderson et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle
- (2012) Matthew A. Deardorff et al. NATURE
- A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
- (2012) Laurens Kruidenier et al. NATURE
- EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
- (2012) Michael T. McCabe et al. NATURE
- Whole-genome sequence of Schistosoma haematobium
- (2012) Neil D Young et al. NATURE GENETICS
- Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
- (2012) Tino Schenk et al. NATURE MEDICINE
- Epigenetic protein families: a new frontier for drug discovery
- (2012) Cheryl H. Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Non-coding RNAs in schistosomes: an unexplored world
- (2011) Katia C Oliveira et al. ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
- Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors
- (2011) Silviya D. Furdas et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Identification of Schistosoma mansoni microRNAs
- (2011) Mariana C Simões et al. BMC GENOMICS
- Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains
- (2011) Chun-wa Chung et al. JOURNAL OF MEDICINAL CHEMISTRY
- Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
- (2011) Marcus Bantscheff et al. NATURE BIOTECHNOLOGY
- How were new medicines discovered?
- (2011) David C. Swinney et al. NATURE REVIEWS DRUG DISCOVERY
- Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
- (2011) J. Du et al. SCIENCE
- Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni
- (2011) Kathrin K. Geyer et al. Nature Communications
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- (2011) Pengfei Cai et al. PLoS Neglected Tropical Diseases
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- (2010) Alice J. Norton et al. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
- Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases
- (2010) James Dowden et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2010) Lili Hao et al. BMC GENOMICS
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- (2010) Anna M. Eiring et al. CELL
- Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor
- (2010) Erin M. Bowers et al. CHEMISTRY & BIOLOGY
- Chemical biology of Histone acetyltransferase natural compounds modulators
- (2010) Fabrizio Dal Piaz et al. MOLECULAR DIVERSITY
- Suppression of inflammation by a synthetic histone mimic
- (2010) Edwige Nicodeme et al. NATURE
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- (2010) Panagis Filippakopoulos et al. NATURE
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- (2010) Colette Dissous et al. TRENDS IN PARASITOLOGY
- RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening
- (2010) Saša Štefanić et al. PLoS Neglected Tropical Diseases
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- (2010) Zhangxun Wang et al. PLoS Neglected Tropical Diseases
- The Emerging Therapeutic Potential of Histone Methyltransferase and Demethylase Inhibitors
- (2009) Astrid Spannhoff et al. ChemMedChem
- Solving the Dnmt2 enigma
- (2009) Matthias Schaefer et al. CHROMOSOMA
- Reactivity of isothiazolones and isothiazolone-1-oxides in the inhibition of the PCAF histone acetyltransferase
- (2009) Massimo Ghizzoni et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility
- (2009) Shanta M. Messerli et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni
- (2009) Florence Dubois et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation
- (2009) Sebastian Greiss et al. MOLECULES AND CELLS
- The genome of the blood fluke Schistosoma mansoni
- (2009) Matthew Berriman et al. NATURE
- The Schistosomiasis Control Initiative (SCI): rationale, development and implementation from 2002–2008
- (2009) A. FENWICK et al. PARASITOLOGY
- Genome-Wide Identification of Schistosoma japonicum MicroRNAs Using a Deep-Sequencing Approach
- (2009) Jian Huang et al. PLoS One
- Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni
- (2009) Sandra D. Melman et al. PLoS Neglected Tropical Diseases
- Protein acetylation sites mediated by Schistosoma mansoni GCN5
- (2008) Renata de Moraes Maciel et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis
- (2008) Michael J Doenhoff et al. CURRENT OPINION IN INFECTIOUS DISEASES
- Schistosoma mansoni: Developmental arrest of miracidia treated with histone deacetylase inhibitors
- (2008) A. Azzi et al. EXPERIMENTAL PARASITOLOGY
- Cloning of SmNCoA-62, a novel nuclear receptor co-activator from Schistosoma mansoni: Assembly of a complex with a SmRXR1/SmNR1 heterodimer, SmGCN5 and SmCBP1
- (2008) Marcelo Rosado Fantappié et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine
- (2008) Carlo Stresemann et al. INTERNATIONAL JOURNAL OF CANCER
- Identification of oxadiazoles as new drug leads for the control of schistosomiasis
- (2008) Ahmed A Sayed et al. NATURE MEDICINE
- Identification and Characterization of Novel MicroRNAs from Schistosoma japonicum
- (2008) Xiangyang Xue et al. PLoS One
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