- Home
- Publications
- Publication Search
- Publication Details
Title
Immunosuppressants in cancer prevention and therapy
Authors
Keywords
-
Journal
OncoImmunology
Volume 2, Issue 12, Pages e26961
Publisher
Informa UK Limited
Online
2014-01-25
DOI
10.4161/onci.26961
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Quantifying pharmacologic suppression of cellular senescence: prevention of cellular hypertrophy versus preservation of proliferative potential
- (2016) Zoya N. Demidenko et al. Aging-US
- Growth and aging: a common molecular mechanism
- (2016) Mikhail V. Blagosklonny et al. Aging-US
- mTOR's role in ageing: protein synthesis or autophagy?
- (2016) Sarah L. Hands et al. Aging-US
- DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence
- (2016) Olga V. Leontieva et al. Aging-US
- P53 and aging: A fresh look at an old paradigm
- (2016) Masha V. Poyurovsky et al. Aging-US
- p53, ROS and senescence in the control of aging
- (2016) Arnaud Vigneron et al. Aging-US
- TP53 and MTOR crosstalk to regulate cellular senescence
- (2016) Lorenzo Galluzzi et al. Aging-US
- Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice
- (2016) Vladimir N. Anisimov et al. Aging-US
- Metformin for aging and cancer prevention
- (2016) Vladimir N. Anisimov Aging-US
- Hormesis does not make sense except in the light of TOR-driven aging
- (2016) Mikhail V. Blagosklonny Aging-US
- Be quiet and you'll keep young: does mTOR underlie p53 action in protecting against senescence by favoring quiescence?
- (2016) Vjekoslav Dulic Aging-US
- Leukemogenesis and ageing: ‘fit for transformation’ ?
- (2016) Mel Greaves Aging-US
- Conserved role of Ras-GEFs in promoting aging: from yeast to mice
- (2016) Mario G. Mirisola et al. Aging-US
- mTOR pathway activation in age-related retinal disease
- (2016) Chen Zhao et al. Aging-US
- Rapamycin: Killing two birds with one stone
- (2016) Amit Khanna et al. Aging-US
- Intermittent supplementation with rapamycin as a dietary restriction mimetic
- (2016) Valter D Longo et al. Aging-US
- Molecular damage in cancer: an argument for mTOR-driven aging
- (2016) Mikhail V. Blagosklonny Aging-US
- Reversing the aging stromal phenotype prevents carcinoma initiation
- (2016) Davina A. Lewis et al. Aging-US
- Aging-Associated Changes in Hematopoiesis and Leukemogenesis: What's the Connection?
- (2016) Curtis J. Henry et al. Aging-US
- Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex
- (2016) Philippe Major Aging-US
- RasGrf1 deficiency delays aging in mice
- (2016) Consuelo Borrás et al. Aging-US
- If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice
- (2016) Vladimir N. Anisimov et al. Aging-US
- Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to
- (2016) Mikhail V. Blagosklonny Aging-US
- Tumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?
- (2016) Mikhail V. Blagosklonny Aging-US
- Matters of life and breath: A role for hypoxia in determining cell state
- (2016) Marco Demaria et al. Aging-US
- Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency
- (2016) Lawrence A. Donehower Aging-US
- Answering the ultimate question “What is the Proximal Cause of Aging?”
- (2016) Mikhail V. Blagosklonny Aging-US
- Geropotency: Increased malignant potential of aging neural progenitors
- (2016) Andrei M. Mikheev et al. Aging-US
- Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice
- (2016) Elena A. Komarova et al. Aging-US
- cep-1/p53-dependent dysplastic pathology of the aging C. elegans gonad
- (2016) Mathew D. McGee et al. Aging-US
- Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging
- (2016) Mikhail V. Blagosklonny Aging-US
- Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling
- (2016) H. Dorota Halicka et al. Aging-US
- Caloric restriction: is mammalian life extension linked to p53?
- (2016) Paola Tucci Aging-US
- How to save Medicare: the anti-aging remedy
- (2016) Mikhail V. Blagosklonny Aging-US
- New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis
- (2016) Maria Comas et al. Aging-US
- Metformin in obesity, cancer and aging: addressing controversies
- (2016) Lev M. Berstein Aging-US
- Inflammaging: disturbed interplay between autophagy and inflammasomes
- (2016) Antero Salminen et al. Aging-US
- Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance
- (2016) Lan Ye et al. Aging-US
- Rapamycin extends life span of Rb1+/− mice by inhibiting neuroendocrine tumors
- (2016) Carolina B. Livi et al. Aging-US
- Rapamycin extends life- and health span because it slows aging
- (2016) Mikhail V. Blagosklonny Aging-US
- Temporal mTOR inhibition protects Fbxw7-deficient mice from radiation-induced tumor development
- (2016) Yueyong Liu et al. Aging-US
- The role of inflammation in age-related disease
- (2016) T. Kevin Howcroft et al. Aging-US
- The requirement of p53 for maintaining chromosomal stability during tetraploidization
- (2015) Oncotarget
- Targeting TOR dependence in cancer
- (2015) Oncotarget
- Targeting the PI3K/Akt/mTOR Pathway – Beyond Rapalogs
- (2015) Oncotarget
- Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence
- (2015) Suzan K Chao et al. Oncotarget
- Will PI3K pathway inhibitors be effective as single agents in patients with cancer?
- (2015) Joan T. Garrett et al. Oncotarget
- Pharmacological manipulation of the cell cycle and metabolism to protect normal tissues against conventional anticancer drugs
- (2015) Ingeborg van Leeuwen et al. Oncotarget
- Targeting mTOR for the treatment of AML. New agents and new directions.
- (2015) Jessica K. Altman et al. Oncotarget
- Metformin: Multi-faceted protection against cancer
- (2015) Sonia Del Barco et al. Oncotarget
- Is human cytomegalovirus a target in cancer therapy?
- (2015) John Inge Johnsen et al. Oncotarget
- Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture
- (2015) Pasha Apontes et al. Oncotarget
- Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment
- (2015) Alberto M. Martelli et al. Oncotarget
- Exploiting the mTOR paradox for disease prevention
- (2015) Ramiro Iglesias-Bartolome et al. Oncotarget
- Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI’s provocative questions
- (2015) Mikhail V. Blagosklonny Oncotarget
- The promise of dual targeting Akt/mTOR signaling in lethal prostate cancer
- (2015) Nicolas Floc'h et al. Oncotarget
- mTOR inhibitor efficacy is determined by the eIF4E/4E-BP ratio
- (2015) Tommy Alain et al. Oncotarget
- A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia
- (2015) Francesca Chiarini et al. Oncotarget
- PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes
- (2015) Filip Janku et al. Oncotarget
- The Interfaces Between Signal Transduction Pathways: IGF-1/mTor, p53 and the Parkinson Disease Pathway
- (2015) Arnold J. Levine et al. Oncotarget
- Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets.
- (2015) Pamela L. Strissel et al. Oncotarget
- Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels
- (2015) Daniela Bressanin et al. Oncotarget
- Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance
- (2015) James Andrew McCubrey et al. Oncotarget
- Selective anticancer agents suppress aging in Drosophila
- (2015) Anton Danilov et al. Oncotarget
- Late-life rapamycin treatment reverses age-related heart dysfunction
- (2013) James M. Flynn et al. AGING CELL
- On mTOR nomenclature
- (2013) Michael N. Hall BIOCHEMICAL SOCIETY TRANSACTIONS
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Immunosurveillance against tetraploidization-induced colon tumorigenesis
- (2013) Alice Boilève et al. CELL CYCLE
- MEK drives cyclin D1 hyperelevation during geroconversion
- (2013) O V Leontieva et al. CELL DEATH AND DIFFERENTIATION
- mTOR in aging, metabolism, and cancer
- (2013) Marion Cornu et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Autophagy and Cellular Immune Responses
- (2013) Yuting Ma et al. IMMUNITY
- mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice
- (2013) Stefan Thiem et al. JOURNAL OF CLINICAL INVESTIGATION
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
- (2013) Tamara Tchkonia et al. JOURNAL OF CLINICAL INVESTIGATION
- mTOR is a key modulator of ageing and age-related disease
- (2013) Simon C. Johnson et al. NATURE
- mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin
- (2013) S. A. Kang et al. SCIENCE
- Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet
- (2013) O V Leontieva et al. Cell Death & Disease
- p53 induces transcriptional and translational programs to suppress cell proliferation and growth
- (2013) Fabricio Loayza-Puch et al. GENOME BIOLOGY
- ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy
- (2013) Yuting Ma et al. OncoImmunology
- Trial watch
- (2013) Erika Vacchelli et al. OncoImmunology
- Rapamycin slows aging in mice
- (2012) John E. Wilkinson et al. AGING CELL
- Caveolin-1 and Accelerated Host Aging in the Breast Tumor Microenvironment
- (2012) Isabelle Mercier et al. AMERICAN JOURNAL OF PATHOLOGY
- Prospective Treatment of Age-Related Diseases by Slowing Down Aging
- (2012) Mikhail V. Blagosklonny AMERICAN JOURNAL OF PATHOLOGY
- Prevention of Age-Related Macular Degeneration–Like Retinopathy by Rapamycin in Rats
- (2012) Nataliya G. Kolosova et al. AMERICAN JOURNAL OF PATHOLOGY
- Randomized Controlled Trial of Sirolimus for Renal Transplant Recipients at High Risk for Nonmelanoma Skin Cancer
- (2012) S. B. Campbell et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Hypoxia, MTOR and autophagy
- (2012) Mikhail V. Blagosklonny Autophagy
- Rapalogs in cancer prevention
- (2012) Mikhail V. Blagosklonny CANCER BIOLOGY & THERAPY
- Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice
- (2012) Vladimir N. Anisimov et al. CELL CYCLE
- Dissecting the role of mTOR complexes in cellular senescence
- (2012) Manuel Serrano CELL CYCLE
- Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence
- (2012) Marina Kolesnichenko et al. CELL CYCLE
- Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells
- (2012) Olga V. Leontieva et al. CELL CYCLE
- Chronological and replicative lifespan in yeast
- (2012) Michael Polymenis et al. CELL CYCLE
- mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis
- (2012) Ramiro Iglesias-Bartolome et al. Cell Stem Cell
- Enteric-delivered rapamycin enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence
- (2012) Cecilia A. Hinojosa et al. EXPERIMENTAL GERONTOLOGY
- Inhibition of Mechanistic Target of Rapamycin Promotes Dendritic Cell Activation and Enhances Therapeutic Autologous Vaccination in Mice
- (2012) E. Amiel et al. JOURNAL OF IMMUNOLOGY
- Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice
- (2012) J. Halloran et al. NEUROSCIENCE
- Sirolimus and Secondary Skin-Cancer Prevention in Kidney Transplantation
- (2012) Sylvie Euvrard et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hypoxia suppresses conversion from proliferative arrest to cellular senescence
- (2012) O. V. Leontieva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
- (2012) D. W. Lamming et al. SCIENCE
- Rapamycin
- (2012) Rupesh K. Srivastava et al. OncoImmunology
- Immune surveillance of pre-cancerous senescent hepatocytes limits hepatocellular carcinoma development
- (2012) Tetyana Yevsa et al. OncoImmunology
- A perspective on new immune adjuvant principles
- (2012) George C. Prendergast et al. OncoImmunology
- Anticancer activity of cardiac glycosides
- (2012) Oliver Kepp et al. OncoImmunology
- Cytomegalovirus infection in brain tumors
- (2012) Cecilia Söderberg-Nauclér et al. OncoImmunology
- IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan
- (2012) Richard Metz et al. OncoImmunology
- Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease
- (2012) Satoko Fujii et al. OncoImmunology
- Autophagy-assisted antigen cross-presentation
- (2012) Yongxiang Yi et al. OncoImmunology
- An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells
- (2012) Laura Senovilla et al. OncoImmunology
- Limiting Hepatitis C Virus Progression in Liver Transplant Recipients Using Sirolimus-Based Immunosuppression
- (2011) G. J. McKenna et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Sirolimus Enhances the Magnitude and Quality of Viral-Specific CD8+ T-Cell Responses to Vaccinia Virus Vaccination in Rhesus Macaques
- (2011) A. P. Turner et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Temsirolimus, an mTOR inhibitor, enhances anti-tumour effects of heat shock protein cancer vaccines
- (2011) Y Wang et al. BRITISH JOURNAL OF CANCER
- Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain tumors
- (2011) Diana L. Thomas et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Rapamycin Is a Potent Inhibitor of Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate
- (2011) L. Allyson Checkley et al. Cancer Prevention Research
- Rapamycin and mTORC1 Inhibition in the Mouse: Skin Cancer Prevention
- (2011) Mohammad Athar et al. Cancer Prevention Research
- Autophagy and Aging
- (2011) David C. Rubinsztein et al. CELL
- Rapamycin decelerates cellular senescence
- (2011) Zoya N. Demidenko et al. CELL CYCLE
- Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo
- (2011) Vladimir N. Anisimov et al. CELL CYCLE
- mTOR signaling in disease
- (2011) Eva Dazert et al. CURRENT OPINION IN CELL BIOLOGY
- Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control
- (2011) Robbie Loewith et al. GENETICS
- Rapamycin passes the torch: a new generation of mTOR inhibitors
- (2011) Don Benjamin et al. NATURE REVIEWS DRUG DISCOVERY
- Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer
- (2011) José Baselga et al. NEW ENGLAND JOURNAL OF MEDICINE
- PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs
- (2011) B Weigelt et al. ONCOGENE
- Mammalian target of rapamycin signal inhibitors could play a role in the treatment of BK polyomavirus nephritis in renal allograft recipients
- (2011) A.I. Sánchez Fructuoso et al. Transplant Infectious Disease
- Lower Malignancy Rates in Renal Allograft Recipients Converted to Sirolimus-Based, Calcineurin Inhibitor-Free Immunotherapy: 24-Month Results From the CONVERT Trial
- (2011) Josefina Alberú et al. TRANSPLANTATION
- Rapamycin Extends Maximal Lifespan in Cancer-Prone Mice
- (2010) Vladimir N. Anisimov et al. AMERICAN JOURNAL OF PATHOLOGY
- Switch to a Sirolimus-Based Immunosuppression in Long-Term Renal Transplant Recipients: Reduced Rate of (Pre-)Malignancies and Nonmelanoma Skin Cancer in a Prospective, Randomized, Assessor-Blinded, Controlled Clinical Trial
- (2010) R. Salgo et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Potential use of rapamycin in HIV infection
- (2010) Marco Donia et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Prevention of cancer by inhibiting aging
- (2010) Mikhail V Blagosklonny CANCER BIOLOGY & THERAPY
- The tumor suppressor p53: Cancer and aging
- (2010) Zhaohui Feng et al. CELL CYCLE
- With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging
- (2010) Pankaj Kapahi et al. Cell Metabolism
- Aging and TOR: interwoven in the fabric of life
- (2010) Zelton Dave Sharp CELLULAR AND MOLECULAR LIFE SCIENCES
- Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network
- (2010) Linda Partridge et al. EXPERIMENTAL GERONTOLOGY
- Cutting Edge: Rapamycin Augments Pathogen-Specific but Not Graft-Reactive CD8+ T Cell Responses
- (2010) I. R. Ferrer et al. JOURNAL OF IMMUNOLOGY
- Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
- (2010) Richard A. Miller et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
- (2010) Shomit Sengupta et al. MOLECULAR CELL
- Can autophagy promote longevity?
- (2010) Frank Madeo et al. NATURE CELL BIOLOGY
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Paradoxical suppression of cellular senescence by p53
- (2010) Z. N. Demidenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rescue Immunosuppression With Mammalian Target of Rapamycin Inhibitor Drugs in Liver Transplantation
- (2010) J.M.A. Mártinez et al. TRANSPLANTATION PROCEEDINGS
- Calorie restriction and cancer prevention: metabolic and molecular mechanisms
- (2010) Valter D. Longo et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
- (2010) E Morselli et al. Cell Death & Disease
- The TOR pathway comes of age
- (2009) Monique N. Stanfel et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Targeting the mTOR Signaling Network for Cancer Therapy
- (2009) Funda Meric-Bernstam et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Randomized Study of Neoadjuvant Everolimus Plus Letrozole Compared With Placebo Plus Letrozole in Patients With Estrogen Receptor–Positive Breast Cancer
- (2009) José Baselga et al. JOURNAL OF CLINICAL ONCOLOGY
- Oral rapamycin reduces tumour burden and vascularization inLkb1+/−mice
- (2009) James Robinson et al. JOURNAL OF PATHOLOGY
- mTOR regulates memory CD8 T-cell differentiation
- (2009) Koichi Araki et al. NATURE
- mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
- (2009) C. Chen et al. Science Signaling
- Mammalian Target of Rapamycin: Discovery of Rapamycin Reveals a Signaling Pathway Important for Normal and Cancer Cell Growth
- (2009) James J. Gibbons et al. SEMINARS IN ONCOLOGY
- Epstein–Barr virus, rapamycin, and host immune responses
- (2008) Sheri M Krams et al. Current Opinion in Organ Transplantation
- mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization
- (2008) B. Gan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reduced Risk of Cytomegalovirus Infection in Solid Organ Transplant Recipients Treated With Sirolimus: A Pooled Analysis of Clinical Trials
- (2008) L. Demopoulos et al. TRANSPLANTATION PROCEEDINGS
- Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
- (2008) Jean-Philippe Coppé et al. PLOS BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More