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Title
Rapalogs in cancer prevention
Authors
Keywords
-
Journal
CANCER BIOLOGY & THERAPY
Volume 13, Issue 14, Pages 1349-1354
Publisher
Informa UK Limited
Online
2012-12-11
DOI
10.4161/cbt.22859
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Note: Only part of the references are listed.- Growth and aging: a common molecular mechanism
- (2016) Mikhail V. Blagosklonny et al. Aging-US
- Fasting and cancer treatment in humans: A case series report
- (2016) Fernando M. Safdie et al. Aging-US
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- (2016) Carl G. Maki Aging-US
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- (2016) Masha V. Poyurovsky et al. Aging-US
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- (2016) Marjon A. Smit et al. Aging-US
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- (2016) Arnaud Vigneron et al. Aging-US
- TP53 and MTOR crosstalk to regulate cellular senescence
- (2016) Lorenzo Galluzzi et al. Aging-US
- P66SHC and Ageing: ROS and TOR?
- (2016) Giovambattista Pani Aging-US
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- (2016) Mikhail V. Blagosklonny Aging-US
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- (2016) Robi Tacutu et al. Aging-US
- Aging-Associated Changes in Hematopoiesis and Leukemogenesis: What's the Connection?
- (2016) Curtis J. Henry et al. Aging-US
- PI3Kα Inhibitors That Inhibit Metastasis
- (2015) Oncotarget
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- (2015) Oncotarget
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- (2015) Oncotarget
- A beta version of life: p110β takes center stage
- (2015) Oncotarget
- The Phosphatidylinositol 3-kinase/AKT/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients
- (2015) Oncotarget
- Targeting the PI3K/Akt/mTOR Pathway – Beyond Rapalogs
- (2015) Oncotarget
- Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence
- (2015) Suzan K Chao et al. Oncotarget
- Will PI3K pathway inhibitors be effective as single agents in patients with cancer?
- (2015) Joan T. Garrett et al. Oncotarget
- Pharmacological manipulation of the cell cycle and metabolism to protect normal tissues against conventional anticancer drugs
- (2015) Ingeborg van Leeuwen et al. Oncotarget
- Targeting mTOR for the treatment of AML. New agents and new directions.
- (2015) Jessica K. Altman et al. Oncotarget
- Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells
- (2015) Genevieve L. Weber et al. Oncotarget
- Involvement of Akt-1 and mTOR in Sensitivity of Breast Cancer to Targeted Therapy
- (2015) Melissa L. Sokolosky et al. Oncotarget
- Phosphorylation of AKT: a Mutational Analysis.
- (2015) Jonathan R. Hart et al. Oncotarget
- Exploiting the mTOR paradox for disease prevention
- (2015) Ramiro Iglesias-Bartolome et al. Oncotarget
- Rapamycin slows aging in mice
- (2012) John E. Wilkinson et al. AGING CELL
- Caveolin-1 and Accelerated Host Aging in the Breast Tumor Microenvironment
- (2012) Isabelle Mercier et al. AMERICAN JOURNAL OF PATHOLOGY
- Prospective Treatment of Age-Related Diseases by Slowing Down Aging
- (2012) Mikhail V. Blagosklonny AMERICAN JOURNAL OF PATHOLOGY
- Prevention of Age-Related Macular Degeneration–Like Retinopathy by Rapamycin in Rats
- (2012) Nataliya G. Kolosova et al. AMERICAN JOURNAL OF PATHOLOGY
- Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?
- (2012) David Gems et al. ANTIOXIDANTS & REDOX SIGNALING
- Pharmacologic synergy between dual phosphoinositide-3-kinase and mammalian target of rapamycin inhibition and 5-Fluorouracil inPIK3CAmutant gastric cancer cells
- (2012) Bhaskar Bhattacharya et al. CANCER BIOLOGY & THERAPY
- Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice
- (2012) Vladimir N. Anisimov et al. CELL CYCLE
- Rapamycin slows aging in mice
- (2012) Adam Spong et al. CELL CYCLE
- Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence
- (2012) Marina Kolesnichenko et al. CELL CYCLE
- mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis
- (2012) Ramiro Iglesias-Bartolome et al. Cell Stem Cell
- Ageing as a Risk Factor for Disease
- (2012) Teresa Niccoli et al. CURRENT BIOLOGY
- Health Span Approximates Life Span Among Many Supercentenarians: Compression of Morbidity at the Approximate Limit of Life Span
- (2012) S. L. Andersen et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Rapamycin Ameliorates Age-Dependent Obesity Associated with Increased mTOR Signaling in Hypothalamic POMC Neurons
- (2012) Shi-Bing Yang et al. NEURON
- Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy
- (2012) C. Lee et al. Science Translational Medicine
- A New Path to Longevity
- (2012) David Stipp SCIENTIFIC AMERICAN
- Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling
- (2011) Smita Majumder et al. AGING CELL
- A longer and healthier life with TOR down-regulation: genetics and drugs: Figure 1
- (2011) Ivana Bjedov et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Identification of Akt-selective cytotoxic compounds that enhance cytotoxic responses to rapamycin
- (2011) Jennifer F. Barger et al. CANCER BIOLOGY & THERAPY
- The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells
- (2011) Hongxia Li et al. CANCER BIOLOGY & THERAPY
- Rapamycin Is a Potent Inhibitor of Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate
- (2011) L. Allyson Checkley et al. Cancer Prevention Research
- Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence
- (2011) Zoya N. Demidenko et al. CELL CYCLE
- TOR-driven aging: Speeding car without brakes
- (2011) Mikhail V Blagosklonny CELL CYCLE
- The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions
- (2011) Elizabeth M. Matthew et al. CELL CYCLE
- Aging-suppressants: Cellular senescence (hyperactivation) and its pharmacologic deceleration
- (2011) Mikhail V Blagosklonny CELL CYCLE
- Increasing healthy lifespan by suppressing aging in our lifetime: Preliminary proposal
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- The power of chemotherapeutic engineering: Arresting cell cycle and suppressing senescence to protect from mitotic inhibitors
- (2011) Mikhail V Blagosklonny CELL CYCLE
- mTOR signaling in disease
- (2011) Eva Dazert et al. CURRENT OPINION IN CELL BIOLOGY
- Rapamycin Extends Maximal Lifespan in Cancer-Prone Mice
- (2010) Vladimir N. Anisimov et al. AMERICAN JOURNAL OF PATHOLOGY
- Prevention of cancer by inhibiting aging
- (2010) Mikhail V Blagosklonny CANCER BIOLOGY & THERAPY
- Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index
- (2010) C. Lee et al. CANCER RESEARCH
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- (2010) Zoya N. Demidenko et al. CELL CYCLE
- Shifting senescence into quiescence by turning up p53
- (2010) Manuel Serrano CELL CYCLE
- Rapamycin and quasi-programmed aging: Four years later
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- Fasting and differential chemotherapy protection in patients
- (2010) Lizzia Raffaghello et al. CELL CYCLE
- Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
- (2010) Ivana Bjedov et al. Cell Metabolism
- Aging and TOR: interwoven in the fabric of life
- (2010) Zelton Dave Sharp CELLULAR AND MOLECULAR LIFE SCIENCES
- Dietary Interventions to Extend Life Span and Health Span Based on Calorie Restriction
- (2010) R. K. Minor et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
- (2010) Richard A. Miller et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
- (2010) Shomit Sengupta et al. MOLECULAR CELL
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- FDA Approval Summary: Temsirolimus as Treatment for Advanced Renal Cell Carcinoma
- (2010) V. E. Kwitkowski et al. ONCOLOGIST
- Paradoxical suppression of cellular senescence by p53
- (2010) Z. N. Demidenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extending Healthy Life Span--From Yeast to Humans
- (2010) L. Fontana et al. SCIENCE
- Calorie restriction and cancer prevention: metabolic and molecular mechanisms
- (2010) Valter D. Longo et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Linking calorie restriction to longevity through sirtuins and autophagy: any role for TOR
- (2010) M V Blagosklonny Cell Death & Disease
- The TOR pathway comes of age
- (2009) Monique N. Stanfel et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Oral rapamycin reduces tumour burden and vascularization inLkb1+/−mice
- (2009) James Robinson et al. JOURNAL OF PATHOLOGY
- Pharmacological Inhibition of Phosphoinositide 3 and TOR Kinases Improves Survival of Drosophila melanogaster
- (2009) A.A. Moskalev et al. REJUVENATION RESEARCH
- Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
- (2009) C. Selman et al. SCIENCE
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