MEK drives cyclin D1 hyperelevation during geroconversion

Radiation-induced cellular senescence results from a slippage of long-term G2arrested cells into G1phase

(2013) Caiyong Ye et al.   CELL CYCLE

Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

(2013) X. Deschenes-Simard et al.   GENES & DEVELOPMENT

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

Running m(o)TOR with the brakes on leads to catastrophe at mitosis

(2012) Zbigniew Darzynkiewicz   CELL CYCLE

Hypoxia and gerosuppression: The mTOR saga continues

(2012) Olga V. Leontieva et al.   CELL CYCLE

Dissecting the role of mTOR complexes in cellular senescence

(2012) Manuel Serrano   CELL CYCLE

Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence

(2012) Marina Kolesnichenko et al.   CELL CYCLE

Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells

(2012) Olga V. Leontieva et al.   CELL CYCLE

Cyclin D1 goes metabolic

(2012) Karen E. Knudsen   CELL CYCLE

Suppression of replicative senescence by rapamycin in rodent embryonic cells

(2012) Tatyana V. Pospelova et al.   CELL CYCLE

Hypoxia suppresses conversion from proliferative arrest to cellular senescence

(2012) O. V. Leontieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells

(2012) J Cahu et al.   Cell Death & Disease

Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence

(2011) Zoya N. Demidenko et al.   CELL CYCLE

Rapamycin decelerates cellular senescence

(2011) Zoya N. Demidenko et al.   CELL CYCLE

Reviewing once more the c-myc and Ras collaboration

(2011) Chenguang Wang et al.   CELL CYCLE

A set of miRNAs participates in the cellular senescence program in human diploid fibroblasts

(2011) R Faraonio et al.   CELL DEATH AND DIFFERENTIATION

Cyclin D1 multitasks

(2011) Jiri Bartek et al.   NATURE

Elimination of Proliferating Cells Unmasks the Shift from Senescence to Quiescence Caused by Rapamycin

(2011) Olga V. Leontieva et al.   PLoS One

ERK Crosstalks with 4EBP1 to Activate Cyclin D1 Translation during Quinol-Thioether–Induced Tuberous Sclerosis Renal Cell Carcinoma

(2011) Jennifer D. Cohen et al.   TOXICOLOGICAL SCIENCES

Growth stimulation leads to cellular senescence when the cell cycle is blocked

(2010) Zoya N. Demidenko et al.   CELL CYCLE

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

(2010) F. Rodier et al.   JOURNAL OF CELL SCIENCE

Paradoxical suppression of cellular senescence by p53

(2010) Z. N. Demidenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells

(2009) R. J. Salmond et al.   JOURNAL OF IMMUNOLOGY

F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage

(2009) Manas K. Santra et al.   NATURE

Oncogenic MAPK Signaling Stimulates mTORC1 Activity by Promoting RSK-Mediated Raptor Phosphorylation

(2008) Audrey Carrière et al.   CURRENT BIOLOGY

Transcriptional regulation of the cyclin D1 gene at a glance

(2008) E. A. Klein et al.   JOURNAL OF CELL SCIENCE