New insights into hepatitis B virus biology and implications for novel antiviral strategies
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
New insights into hepatitis B virus biology and implications for novel antiviral strategies
Authors
Keywords
-
Journal
National Science Review
Volume 2, Issue 3, Pages 296-313
Publisher
Oxford University Press (OUP)
Online
2015-09-13
DOI
10.1093/nsr/nwv044
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice
- (2015) Yuji Ishida et al. AMERICAN JOURNAL OF PATHOLOGY
- Immunological aspects of antiviral therapy of chronic hepatitis B virus and hepatitis C virus infections
- (2015) Barbara Rehermann et al. HEPATOLOGY
- Age-related immune clearance of hepatitis B virus infection requires the establishment of gut microbiota
- (2015) Han-Hsuan Chou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular biology of hepatitis B virus infection
- (2015) Christoph Seeger et al. VIROLOGY
- Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease
- (2015) Edward M. Kennedy et al. VIROLOGY
- High persistence rate of hepatitis B virus in a hydrodynamic injection-based transfection model in C3H/HeN mice
- (2015) Xiu-Hua Peng WORLD JOURNAL OF GASTROENTEROLOGY
- Selection of HBV preS1-binding penta-peptides by phage display
- (2014) Yonggang He et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Strategies to eliminate HBV infection
- (2014) Rama Kapoor et al. Future Virology
- Identification of NTCP as an HBV Receptor: The Beginning of the End or the End of the Beginning?
- (2014) Shuping Tong et al. GASTROENTEROLOGY
- Strategies to Inhibit Entry of HBV and HDV Into Hepatocytes
- (2014) Stephan Urban et al. GASTROENTEROLOGY
- Association of Genetic Variation of Sodium Taurocholate Cotransporting Polypeptide with Chronic Hepatitis B Virus Infection
- (2014) Na Li et al. Genetic Testing and Molecular Biomarkers
- Sequences in the terminal protein and reverse transcriptase domains of the hepatitis B virus polymerase contribute to RNA binding and encapsidation
- (2014) F. Cao et al. JOURNAL OF VIRAL HEPATITIS
- Hepatitis B Virus Polymerase Disrupts K63-Linked Ubiquitination of STING To Block Innate Cytosolic DNA-Sensing Pathways
- (2014) Yinghui Liu et al. JOURNAL OF VIROLOGY
- Recombinant Covalently Closed Circular Hepatitis B Virus DNA Induces Prolonged Viral Persistence in Immunocompetent Mice
- (2014) Zhihua Qi et al. JOURNAL OF VIROLOGY
- Viral Entry of Hepatitis B and D Viruses and Bile Salts Transportation Share Common Molecular Determinants on Sodium Taurocholate Cotransporting Polypeptide
- (2014) H. Yan et al. JOURNAL OF VIROLOGY
- Hepatitis B virus infection
- (2014) Christian Trépo et al. LANCET
- Immunosuppressive Drugs Modulate the Replication of Hepatitis B Virus (HBV) in a Hydrodynamic Injection Mouse Model
- (2014) Junzhong Wang et al. PLoS One
- Susceptibility of Different Hepatitis B Virus Isolates to Interferon-Alpha in a Mouse Model Based on Hydrodynamic Injection
- (2014) Jingjiao Song et al. PLoS One
- Transcription of Hepatitis B Virus Covalently Closed Circular DNA Is Regulated by CpG Methylation during Chronic Infection
- (2014) Yongmei Zhang et al. PLoS One
- Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
- (2014) A. Shlomai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Encapsidated hepatitis B virus reverse transcriptase is poised on an ordered RNA lattice
- (2014) J. C.-Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Complete replication of hepatitis B virus and hepatitis C virus in a newly developed hepatoma cell line
- (2014) Darong Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses
- (2014) Christian Königer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA
- (2014) J. Lucifora et al. SCIENCE
- The Tudor Domain Protein Spindlin1 Is Involved in Intrinsic Antiviral Defense against Incoming Hepatitis B Virus and Herpes Simplex Virus Type 1
- (2014) Aurélie Ducroux et al. PLoS Pathogens
- Hepatitis B Virus Infection and Immunopathogenesis in a Humanized Mouse Model: Induction of Human-Specific Liver Fibrosis and M2-Like Macrophages
- (2014) Moses T. Bility et al. PLoS Pathogens
- The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo
- (2014) Su-Ru Lin et al. Molecular Therapy-Nucleic Acids
- Interplay between hepatitis B virus and the innate immune responses: implications for new therapeutic strategies
- (2014) Jieliang Chen et al. VIROLOGICA SINICA
- A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections
- (2013) Keiichi Kosaka et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP
- (2013) Masashi Iwamoto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A mouse model for HBV immunotolerance and immunotherapy
- (2013) Dan Yang et al. Cellular & Molecular Immunology
- Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes
- (2013) Yi Ni et al. GASTROENTEROLOGY
- Discovery of naturally occurring transmissible chronic hepatitis B virus infection among Macaca fascicularis from mauritius island
- (2013) Tatiana Dupinay et al. HEPATOLOGY
- 378 HEPATITIS B CORE (HBC) PROTEIN IS A KEY AND VERY EARLY NEGATIVE REGULATOR OF THE INTERFERON RESPONSE
- (2013) M. Gruffaz et al. JOURNAL OF HEPATOLOGY
- Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration
- (2013) Lena Allweiss et al. JOURNAL OF HEPATOLOGY
- Cyclosporin A inhibits hepatitis B and hepatitis D virus entry by cyclophilin-independent interference with the NTCP receptor
- (2013) Shirin Nkongolo et al. JOURNAL OF HEPATOLOGY
- Hepatitis B Virus Surface Antigen Selectively Inhibits TLR2 Ligand-Induced IL-12 Production in Monocytes/Macrophages by Interfering with JNK Activation
- (2013) S. Wang et al. JOURNAL OF IMMUNOLOGY
- A New Cell Culture System for Infection with Hepatitis B Virus that Fuses HepG2 Cells with Primary Human Hepatocytes
- (2013) Y Jiang et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Adeno-Associated Virus-Mediated Gene Transfer Leads to Persistent Hepatitis B Virus Replication in Mice Expressing HLA-A2 and HLA-DR1 Molecules
- (2013) S. Dion et al. JOURNAL OF VIROLOGY
- Molecular Determinants of Hepatitis B and D Virus Entry Restriction in Mouse Sodium Taurocholate Cotransporting Polypeptide
- (2013) H. Yan et al. JOURNAL OF VIROLOGY
- Novel Recombinant Hepatitis B Virus Vectors Efficiently Deliver Protein and RNA Encoding Genes into Primary Hepatocytes
- (2013) R. Hong et al. JOURNAL OF VIROLOGY
- Comparative Analysis of Hepatitis B Virus Polymerase Sequences Required for Viral RNA Binding, RNA Packaging, and Protein Priming
- (2013) S. A. Jones et al. JOURNAL OF VIROLOGY
- Sulfamoylbenzamide Derivatives Inhibit the Assembly of Hepatitis B Virus Nucleocapsids
- (2013) M. R. Campagna et al. JOURNAL OF VIROLOGY
- Methyltransferase PRMT1 Is a Binding Partner of HBx and a Negative Regulator of Hepatitis B Virus Transcription
- (2013) S. Benhenda et al. JOURNAL OF VIROLOGY
- An Efficient Antiviral Strategy for Targeting Hepatitis B Virus Genome Using Transcription Activator-Like Effector Nucleases
- (2013) Jieliang Chen et al. MOLECULAR THERAPY
- Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity
- (2013) Jianhua Li et al. NATURE IMMUNOLOGY
- Alpha-Interferon Suppresses Hepadnavirus Transcription by Altering Epigenetic Modification of cccDNA Minichromosomes
- (2013) Fei Liu et al. PLoS Pathogens
- The Hepatitis B Virus Ribonuclease H Is Sensitive to Inhibitors of the Human Immunodeficiency Virus Ribonuclease H and Integrase Enzymes
- (2013) John E. Tavis et al. PLoS Pathogens
- Hepatitis B virus reverse transcriptase: diverse functions as classical and emerging targets for antiviral intervention
- (2013) Scott A Jones et al. Emerging Microbes & Infections
- Identification of Disubstituted Sulfonamide Compounds as Specific Inhibitors of Hepatitis B Virus Covalently Closed Circular DNA Formation
- (2012) Dawei Cai et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The innate immune response to hepatitis B virus infection: Implications for pathogenesis and therapy
- (2012) Jinhong Chang et al. ANTIVIRAL RESEARCH
- Ezetimibe blocks hepatitis B virus infection after virus uptake into hepatocytes
- (2012) Julie Lucifora et al. ANTIVIRAL RESEARCH
- Transfer of HBV Genomes Using Low Doses of Adenovirus Vectors Leads to Persistent Infection in Immune Competent Mice
- (2012) Li–Rung Huang et al. GASTROENTEROLOGY
- Hepatitis B virus polymerase impairs interferon-α-induced STA T activation through inhibition of importin-α5 and protein kinase C-δ
- (2012) Jieliang Chen et al. HEPATOLOGY
- IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome
- (2012) Laura Belloni et al. JOURNAL OF CLINICAL INVESTIGATION
- The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus
- (2012) Tassilo Volz et al. JOURNAL OF HEPATOLOGY
- Carbonyl J Acid Derivatives Block Protein Priming of Hepadnaviral P Protein and DNA-Dependent DNA Synthesis Activity of Hepadnaviral Nucleocapsids
- (2012) Yong-Xiang Wang et al. JOURNAL OF VIROLOGY
- In Vitro Epsilon RNA-Dependent Protein Priming Activity of Human Hepatitis B Virus Polymerase
- (2012) S. A. Jones et al. JOURNAL OF VIROLOGY
- Entry of Hepatitis B Virus into Immortalized Human Primary Hepatocytes by Clathrin-Dependent Endocytosis
- (2012) H.-C. Huang et al. JOURNAL OF VIROLOGY
- Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis
- (2012) Moses T Bility et al. Nature Protocols
- Experimental models and therapeutic approaches for HBV
- (2012) Maura Dandri et al. Seminars in Immunopathology
- Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
- (2012) Huan Yan et al. eLife
- The main Hepatitis B virus (HBV) mutants resistant to nucleoside analogs are susceptible in vitro to non-nucleoside inhibitors of HBV replication
- (2011) Gaëtan Billioud et al. ANTIVIRAL RESEARCH
- Chromosome Remodeling Related to Hepatitis B Virus Replication in HepG2 Cells
- (2011) Qian Gong et al. DNA AND CELL BIOLOGY
- HBc binds to the CpG islands of HBV cccDNA and promotes an epigenetic permissive state
- (2011) Yan-Hai Guo et al. Epigenetics
- 5′ Triphosphorylated Small Interfering RNAs Control Replication of Hepatitis B Virus and Induce an Interferon Response in Human Liver Cells and Mice
- (2011) Gregor Ebert et al. GASTROENTEROLOGY
- Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
- (2011) Antonio Bertoletti et al. GUT
- Reversal of hepatitis B virus-induced immune tolerance by an immunostimulatory 3p-HBx-siRNAs in a retinoic acid inducible gene I-dependent manner
- (2011) Qiuju Han et al. HEPATOLOGY
- Design, Synthesis, and Biological Evaluation of Triazolo-pyrimidine Derivatives as Novel Inhibitors of Hepatitis B Virus Surface Antigen (HBsAg) Secretion
- (2011) Wenquan Yu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Roles of the Envelope Proteins in the Amplification of Covalently Closed Circular DNA and Completion of Synthesis of the Plus-Strand DNA in Hepatitis B Virus
- (2011) T. B. Lentz et al. JOURNAL OF VIROLOGY
- Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment
- (2010) Karl-Dimiter Bissig et al. JOURNAL OF CLINICAL INVESTIGATION
- Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKK and DDX3
- (2010) S. Yu et al. JOURNAL OF GENERAL VIROLOGY
- Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice
- (2010) Thomas Vanwolleghem et al. JOURNAL OF HEPATOLOGY
- Interferons Accelerate Decay of Replication-Competent Nucleocapsids of Hepatitis B Virus
- (2010) C. Xu et al. JOURNAL OF VIROLOGY
- Zinc-finger Nuclease-induced Gene Repair With Oligodeoxynucleotides: Wanted and Unwanted Target Locus Modifications
- (2010) Sarah Radecke et al. MOLECULAR THERAPY
- Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion
- (2010) Haifeng Wang et al. PLoS Pathogens
- Generation of Covalently Closed Circular DNA of Hepatitis B Viruses via Intracellular Recycling Is Regulated in a Virus Specific Manner
- (2010) Josef Köck et al. PLoS Pathogens
- Nucleoporin 153 Arrests the Nuclear Import of Hepatitis B Virus Capsids in the Nuclear Basket
- (2010) André Schmitz et al. PLoS Pathogens
- A Mouse Model of Inducible Liver Injury Caused by Tet-On Regulated Urokinase for Studies of Hepatocyte Transplantation
- (2009) Xijun Song et al. AMERICAN JOURNAL OF PATHOLOGY
- RNA-protein interactions in hepadnavirus reverse transcription
- (2009) Jianming Hu Frontiers in Bioscience-Landmark
- Control of cccDNA function in hepatitis B virus infection
- (2009) Massimo Levrero et al. JOURNAL OF HEPATOLOGY
- The Size of the Viral Inoculum Contributes to the Outcome of Hepatitis B Virus Infection
- (2009) S. Asabe et al. JOURNAL OF VIROLOGY
- Hepatitis B Virus Requires Intact Caveolin-1 Function for Productive Infection in HepaRG Cells
- (2009) A. Macovei et al. JOURNAL OF VIROLOGY
- Fine Mapping of Pre-S Sequence Requirements for Hepatitis B Virus Large Envelope Protein-Mediated Receptor Interaction
- (2009) A. Schulze et al. JOURNAL OF VIROLOGY
- HBsAg inhibits TLR9-mediated activation and IFN-α production in plasmacytoid dendritic cells
- (2009) Yongfen Xu et al. MOLECULAR IMMUNOLOGY
- Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function
- (2009) L. Belloni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear Entry of Hepatitis B Virus Capsids Involves Disintegration to Protein Dimers followed by Nuclear Reassociation to Capsids
- (2009) Birgit Rabe et al. PLoS Pathogens
- Hepatitis B virus infection is dependent on cholesterol in the viral envelope
- (2008) Corinna M. Bremer et al. CELLULAR MICROBIOLOGY
- Comprehensive Genetic and Epigenetic Analysis of Occult Hepatitis B from Liver Tissue Samples
- (2008) Perumal Vivekanandan et al. CLINICAL INFECTIOUS DISEASES
- Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus
- (2008) Marjoleine L. Op den Brouw et al. IMMUNOLOGY
- Persistence of the hepatitis B virus covalently closed circular DNA in HepaRG human hepatocyte-like cells
- (2008) O. Hantz et al. JOURNAL OF GENERAL VIROLOGY
- Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein
- (2008) Joerg Petersen et al. NATURE BIOTECHNOLOGY
- Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication
- (2007) Brent E. Korba et al. ANTIVIRAL RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now