The Hepatitis B Virus Ribonuclease H Is Sensitive to Inhibitors of the Human Immunodeficiency Virus Ribonuclease H and Integrase Enzymes

Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity

(2012) Virginie Suchaud et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antiviral therapies: Focus on hepatitis B reverse transcriptase

(2012) Eleftherios Michailidis et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Probing chelation motifs in HIV integrase inhibitors

(2012) A. Agrawal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging pipeline drugs for hepatitis B infection

(2011) Natravis Cox et al.   EXPERT OPINION ON EMERGING DRUGS

Association of intrahepatic cccDNA reduction with the improvement of liver histology in chronic hepatitis B patients receiving oral antiviral agents

(2011) Pin-Nan Cheng et al.   JOURNAL OF MEDICAL VIROLOGY

Synthesis, Activity, and Structural Analysis of Novel α-Hydroxytropolone Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H

(2011) Suhman Chung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Magnesium Chelating 2-Hydroxyisoquinoline-1,3(2H,4H)-diones, as Inhibitors of HIV-1 Integrase and/or the HIV-1 Reverse Transcriptase Ribonuclease H Domain: Discovery of a Novel Selective Inhibitor of the Ribonuclease H Function

(2011) Muriel Billamboz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Impact of hepatitis B therapy on the long-term outcome of liver disease

(2011) Yun-Fan Liaw   LIVER INTERNATIONAL

Hepatitis B Virus Lacks Immune Activating Capacity, but Actively Inhibits Plasmacytoid Dendritic Cell Function

(2011) Andrea M. Woltman et al.   PLoS One

Lessons From HIV Therapy Applied to Viral Hepatitis Therapy: Summary of a Workshop

(2010) Alexander Monto et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Structure-Activity Analysis of Vinylogous Urea Inhibitors of Human Immunodeficiency Virus-Encoded Ribonuclease H

(2010) S. Chung et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of newer oral antiviral agents on future therapy of chronic hepatitis B

(2010) Robert P Perrillo et al.   ANTIVIRAL THERAPY

Potent and selective HIV-1 ribonuclease H inhibitors based on a 1-hydroxy-1,8-naphthyridin-2(1H)-one scaffold

(2010) Peter D. Williams et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Interaction of HIV-1 Reverse Transcriptase Ribonuclease H with an Acylhydrazone Inhibitor

(2010) Qingguo Gong et al.   Chemical Biology & Drug Design

Tenofovir and Entecavir Are the Most Effective Antiviral Agents for Chronic Hepatitis B: A Systematic Review and Bayesian Meta-analyses

(2010) Gloria Woo et al.   GASTROENTEROLOGY

The cost-effectiveness of alternative strategies against HBV in Italy

(2010) Matteo Ruggeri et al.   HEALTH POLICY

Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients

(2010) Karsten Wursthorn et al.   HEPATOLOGY

Geographical and genetic diversity of the human hepatitis B virus

(2010) Fuat Kurbanov et al.   HEPATOLOGY RESEARCH

Genetic and biochemical diversity in the HCV NS5B RNA polymerase in the context of interferon α plus ribavirin therapy

(2010) F. Cao et al.   JOURNAL OF VIRAL HEPATITIS

Molecular characterization of intrahepatic and extrahepatic hepatitis B virus (HBV) reservoirs in patients on suppressive antiviral therapy

(2010) C. S. Coffin et al.   JOURNAL OF VIRAL HEPATITIS

Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors

(2010) H.-P. Su et al.   JOURNAL OF VIROLOGY

Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion

(2010) Haifeng Wang et al.   PLoS Pathogens

Small molecule inhibitors of HIV RT Ribonuclease H

(2009) Martin Di Grandi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A New Magic Bullet for Chronic Hepatitis B Infection: Is This the End of the Story?

(2009) George K.K. Lau   GASTROENTEROLOGY

Hepatitis B Virus Resistance to Nucleos(t)ide Analogues

(2009) Fabien Zoulim et al.   GASTROENTEROLOGY

Long-term efficacy of tenofovir monotherapy for hepatitis B virus-monoinfected patients after failure of nucleoside/nucleotide analogues

(2009) Florian van Bömmel et al.   HEPATOLOGY

Modeling the cost-effectiveness of different oral antiviral therapies in patients with chronic hepatitis B

(2009) Maria Buti et al.   JOURNAL OF HEPATOLOGY

Control of cccDNA function in hepatitis B virus infection

(2009) Massimo Levrero et al.   JOURNAL OF HEPATOLOGY

RNase H Active Site Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Design, Biochemical Activity, and Structural Information

(2009) Thorsten A. Kirschberg et al.   JOURNAL OF MEDICINAL CHEMISTRY

Derivatives of 5-Nitro-furan-2-carboxylic Acid Carbamoylmethyl Ester Inhibit RNase H Activity Associated with HIV-1 Reverse Transcriptase

(2009) Hideyoshi Fuji et al.   JOURNAL OF MEDICINAL CHEMISTRY

Human immunodeficiency virus: 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus

(2009) Martin Stürmer et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

HBsAg inhibits TLR9-mediated activation and IFN-α production in plasmacytoid dendritic cells

(2009) Yongfen Xu et al.   MOLECULAR IMMUNOLOGY

Structure of HIV-1 Reverse Transcriptase with the Inhibitor β-Thujaplicinol Bound at the RNase H Active Site

(2009) Daniel M. Himmel et al.   STRUCTURE

Vinylogous Ureas as a Novel Class of Inhibitors of Reverse Transcriptase-Associated Ribonuclease H Activity

(2008) Michaela Wendeler et al.   ACS Chemical Biology

Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells

(2008) Jun Wu et al.   HEPATOLOGY

Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus

(2008) Marjoleine L. Op den Brouw et al.   IMMUNOLOGY

Design, Synthesis, and Biological Evaluation of a Series of 2-Hydroxyisoquinoline-1,3(2H,4H)-diones as Dual Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and the Reverse Transcriptase RNase H Domain

(2008) Muriel Billamboz et al.   JOURNAL OF MEDICINAL CHEMISTRY

HIV-1 Ribonuclease H Inhibitory Phenolic Glycosides fromEugenia hyemalis

(2008) Heidi R. Bokesch et al.   JOURNAL OF NATURAL PRODUCTS

Functional and Structural Dynamics of Hepadnavirus Reverse Transcriptase during Protein-Primed Initiation of Reverse Transcription: Effects of Metal Ions

(2008) L. Lin et al.   JOURNAL OF VIROLOGY

Tenofovir Disoproxil Fumarate versus Adefovir Dipivoxil for Chronic Hepatitis B

(2008) Patrick Marcellin et al.   NEW ENGLAND JOURNAL OF MEDICINE