Sirtuins and renal diseases: relationship with aging and diabetic nephropathy

SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice

(2016) Sokrates Stein et al.   Aging-US

The Association Between Age and Nephrosclerosis on Renal Biopsy Among Healthy Adults

(2013) Andrew D. Rule   ANNALS OF INTERNAL MEDICINE

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes

(2011) Shiro Maeda et al.   Clinical and Experimental Nephrology

Tubular Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin

(2011) Yumi Takiyama et al.   DIABETES

Dietary Restriction Ameliorates Diabetic Nephropathy through Anti-Inflammatory Effects and Regulation of the Autophagy via Restoration of Sirt1 in Diabetic Wistar Fatty (fa/fa) Rats: A Model of Type 2 Diabetes

(2011) Munehiro Kitada et al.   Experimental Diabetes Research

Autophagy as a Therapeutic Target in Diabetic Nephropathy

(2011) Yuki Tanaka et al.   Experimental Diabetes Research

Dissecting systemic control of metabolism and aging in the NAD World: The importance of SIRT1 and NAMPT-mediated NAD biosynthesis

(2011) Shin-ichiro Imai   FEBS LETTERS

SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells

(2011) Tetsuro Koyama et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

(2011) Yuki Tanaka et al.   KIDNEY INTERNATIONAL

Nutrition and chronic kidney disease

(2011) Denis Fouque et al.   KIDNEY INTERNATIONAL

Kidney aging—inevitable or preventable?

(2011) Devasmita Choudhury et al.   Nature Reviews Nephrology

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy

(2011) Juan F. Navarro-González et al.   Nature Reviews Nephrology

Sirtuins, Aging, and Medicine

(2011) Leonard Guarente   NEW ENGLAND JOURNAL OF MEDICINE

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

(2011) Nady Braidy et al.   PLoS One

Alteration of Forkhead Box O (Foxo4) Acetylation Mediates Apoptosis of Podocytes in Diabetes Mellitus

(2011) Peter Y. Chuang et al.   PLoS One

Resveratrol Inhibits Renal Fibrosis in the Obstructed Kidney

(2010) Jinhua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model

(2010) X. X. Wang et al.   DIABETES

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP

(2010) A. K. Walker et al.   GENES & DEVELOPMENT

Kidney-specific Overexpression of Sirt1 Protects against Acute Kidney Injury by Retaining Peroxisome Function

(2010) Kazuhiro Hasegawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirt1 activation protects the mouse renal medulla from oxidative injury

(2010) Wenjuan He et al.   JOURNAL OF CLINICAL INVESTIGATION

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

(2010) Shinji Kume et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

(2010) Björn Hartleben et al.   JOURNAL OF CLINICAL INVESTIGATION

The sweet side of HIF

(2010) Volker H. Haase   KIDNEY INTERNATIONAL

Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress

(2010) T. T. Schug et al.   MOLECULAR AND CELLULAR BIOLOGY

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Nuclear hormone receptors in diabetic nephropathy

(2010) Xiaoxin X. Wang et al.   Nature Reviews Nephrology

Endothelial dysfunction as a potential contributor in diabetic nephropathy

(2010) Takahiko Nakagawa et al.   Nature Reviews Nephrology

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Molecular mechanisms of diabetic vascular complications

(2010) Munehiro Kitada et al.   Journal of Diabetes Investigation

SIRT6 protects against pathological damage caused by diet-induced obesity

(2009) Yariv Kanfi et al.   AGING CELL

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

(2009) Takeshi Yoshizaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States

(2009) Jongsook Kim Kemper et al.   Cell Metabolism

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

Sirtuin 1 Functionally and Physically Interacts with Disruptor of Telomeric Silencing-1 to Regulate α-ENaCTranscription in Collecting Duct

(2009) Dongyu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of the Ang II type 1 receptor promotes longevity in mice

(2009) Ariela Benigni et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1

(2009) S. B. Rajamohan et al.   MOLECULAR AND CELLULAR BIOLOGY

Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials

(2009) Nigel A. Calcutt et al.   NATURE REVIEWS DRUG DISCOVERY

SIRT1 and insulin resistance

(2009) Fengxia Liang et al.   Nature Reviews Endocrinology

RAS inhibition: probably not a one-size-fits-all approach

(2009) Drazenka Pongrac Barlovic et al.   Nature Reviews Nephrology

An update on the lipid nephrotoxicity hypothesis

(2009) Xiong Z. Ruan et al.   Nature Reviews Nephrology

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Regulation of Hypoxia-Inducible Factor 2  Signaling by the Stress-Responsive Deacetylase Sirtuin 1

(2009) E. M. Dioum et al.   SCIENCE

SIRT1, an Antiinflammatory and Antiaging Protein, Is Decreased in Lungs of Patients with Chronic Obstructive Pulmonary Disease

(2008) Saravanan Rajendrasozhan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SIRT1, a Longevity Gene, Downregulates Angiotensin II Type 1 Receptor Expression in Vascular Smooth Muscle Cells

(2008) Ryohei Miyazaki et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression

(2008) Kazuhiro Hasegawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Regulation of SIRT6 protein levels by nutrient availability

(2008) Yariv Kanfi et al.   FEBS LETTERS

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY

SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70

(2008) N. R. Sundaresan et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice

(2008) Gino Boily et al.   PLoS One

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduction of proteinuria with angiotensin receptor blockers

(2008) Jan Galle   Nature clinical practice. Cardiovascular medicine