A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research
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Title
A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research
Authors
Keywords
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Journal
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-09-04
DOI
10.3389/fphar.2018.00913
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Note: Only part of the references are listed.- Aprepitant Has Mixed Effects on Nausea and Reduces Other Symptoms in Patients With Gastroparesis and Related Disorders
- (2018) Pankaj J. Pasricha et al. GASTROENTEROLOGY
- CINV: still troubling patients after all these years
- (2018) Matti Aapro SUPPORTIVE CARE IN CANCER
- Domperidone prolongs oral to duodenal transit time in video capsule endoscopy
- (2017) Michael Mcfarlane et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
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- (2017) Gareth J Sanger et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- A randomized, double-blind, placebo-controlled trial of camicinal in Parkinson's disease
- (2017) Sarah L. Marrinan et al. MOVEMENT DISORDERS
- Therapeutic response to domperidone in gastroparesis: A prospective study using the GCSI-daily diary
- (2017) J. Heckert et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Centrally located GLP-1 receptors modulate gastric slow waves and cardiovascular function in ferrets consistent with the induction of nausea
- (2017) Zengbing Lu et al. NEUROPEPTIDES
- Brain Activation by H1 Antihistamines Challenges Conventional View of Their Mechanism of Action in Motion Sickness: A Behavioral, c-Fos and Physiological Study in Suncus murinus (House Musk Shrew)
- (2017) Longlong Tu et al. Frontiers in Physiology
- Relamorelin Reduces Vomiting Frequency and Severity and Accelerates Gastric Emptying in Adults With Diabetic Gastroparesis
- (2016) Anthony Lembo et al. GASTROENTEROLOGY
- Olanzapine in the Management of Difficult to Control Nausea and Vomiting in a Palliative Care Population: A Case Series
- (2016) David MacKintosh JOURNAL OF PALLIATIVE MEDICINE
- What the ancient Greeks and Romans knew (and did not know) about seasickness
- (2016) Doreen Huppert et al. NEUROLOGY
- Current drug treatments targeting dopamine D3 receptor
- (2016) Gian Marco Leggio et al. PHARMACOLOGY & THERAPEUTICS
- 2016 Updated MASCC/ESMO Consensus Recommendations: Prevention of Nausea and Vomiting Following High Emetic Risk Chemotherapy
- (2016) Jørn Herrstedt et al. SUPPORTIVE CARE IN CANCER
- Efficacy of olanzapine for the prophylaxis and rescue of chemotherapy-induced nausea and vomiting (CINV): a systematic review and meta-analysis
- (2016) Leonard Chiu et al. SUPPORTIVE CARE IN CANCER
- Granisetron Transdermal System for Treatment of Symptoms of Gastroparesis: A Prescription Registry Study
- (2016) Deena Midani et al. Journal of Neurogastroenterology and Motility
- The Role of Central and Enteric Nervous Systems in the Control of the Retrograde Giant Contraction
- (2016) Ivan M Lang Journal of Neurogastroenterology and Motility
- Cannabinoids As Potential Treatment for Chemotherapy-Induced Nausea and Vomiting
- (2016) Erin M. Rock et al. Frontiers in Pharmacology
- Moving in a Moving World: A Review on Vestibular Motion Sickness
- (2016) Giovanni Bertolini et al. Frontiers in Neurology
- Measurement and Monitoring of Nausea Severity in Emergency Department Patients: A Comparison of Scales and Exploration of Treatment Efficacy Outcome Measures
- (2015) Robert Meek et al. ACADEMIC EMERGENCY MEDICINE
- Cardiovascular Safety Profile and Clinical Experience With High-Dose Domperidone Therapy for Nausea and Vomiting
- (2015) Arleen Ortiz et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Pathophysiology and treatment of motion sickness
- (2015) John F. Golding et al. CURRENT OPINION IN NEUROLOGY
- Netupitant/Palonosetron: A Review in the Prevention of Chemotherapy-Induced Nausea and Vomiting
- (2015) Gillian M. Keating DRUGS
- Loss of Interstitial Cells of Cajal and Patterns of Gastric Dysrhythmia in Patients With Chronic Unexplained Nausea and Vomiting
- (2015) Timothy R. Angeli et al. GASTROENTEROLOGY
- Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes and glucose homeostasis
- (2015) Bethann S. Hromatka et al. HUMAN MOLECULAR GENETICS
- Intranasal scopolamine affects the semicircular canals centrally and peripherally
- (2015) Aurélie P. Weerts et al. JOURNAL OF APPLIED PHYSIOLOGY
- Visually induced nausea causes characteristic changes in cerebral, autonomic and endocrine function in humans
- (2015) Adam D. Farmer et al. JOURNAL OF PHYSIOLOGY-LONDON
- Ghrelin and motilin receptors as drug targets for gastrointestinal disorders
- (2015) Gareth J. Sanger et al. Nature Reviews Gastroenterology & Hepatology
- Chemotherapy-Induced Nausea and Vomiting: Time for More Emphasis on Nausea?
- (2015) T. L. Ng et al. ONCOLOGIST
- Defining the efficacy of neurokinin-1 receptor antagonists in controlling chemotherapy-induced nausea and vomiting in different emetogenic settings—a meta-analysis
- (2015) Karin Jordan et al. SUPPORTIVE CARE IN CANCER
- A randomized phase III study evaluating the efficacy and safety of NEPA, a fixed-dose combination of netupitant and palonosetron, for prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy
- (2014) M. Aapro et al. ANNALS OF ONCOLOGY
- Brain Circuitry Supporting Multi-Organ Autonomic Outflow in Response to Nausea
- (2014) Roberta Sclocco et al. CEREBRAL CORTEX
- 929a A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of RM-131 in Patients with Diabetic Gastroparesis
- (2014) Anthony Lembo et al. GASTROENTEROLOGY
- Olanzapine for Intractable Nausea and Vomiting in Palliative Care Patients Not Receiving Chemotherapy
- (2014) Sean R. Atkinson JOURNAL OF PALLIATIVE MEDICINE
- Effects of Maropitant Citrate or Acepromazine on the Incidence of Adverse Events Associated with Hydromorphone Premedication in Dogs
- (2014) A.K. Claude et al. JOURNAL OF VETERINARY INTERNAL MEDICINE
- Emerging treatments in Neurogastroenterology: relamorelin: a novel gastrocolokinetic synthetic ghrelin agonist
- (2014) M. Camilleri et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Drugs acting at 5-HT4, D2, motilin, and ghrelin receptors differ markedly in how they affect neuromuscular functions in human isolated stomach
- (2014) J. Broad et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Biased agonism of the μ-opioid receptor by TRV130 increases analgesia and reduces on-target adverse effects versus morphine: A randomized, double-blind, placebo-controlled, crossover study in healthy volunteers
- (2014) David G. Soergel et al. PAIN
- Serotonin 5-HT3 Receptor-Mediated Vomiting Occurs via the Activation of Ca2+/CaMKII-Dependent ERK1/2 Signaling in the Least Shrew (Cryptotis parva)
- (2014) Weixia Zhong et al. PLoS One
- Olanzapine for chemotherapy-induced nausea and vomiting: a systematic review
- (2014) Christopher M. Hocking et al. SUPPORTIVE CARE IN CANCER
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- (2014) Shinjini Kundu WORLD JOURNAL OF GASTROENTEROLOGY
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- (2014) Thomas Guttuso EXPERIMENTAL BRAIN RESEARCH
- Integration of vestibular and emetic gastrointestinal signals that produce nausea and vomiting: potential contributions to motion sickness
- (2014) Bill J. Yates et al. EXPERIMENTAL BRAIN RESEARCH
- Gastric dysrhythmias: a potential objective measure of nausea
- (2014) Kenneth L. Koch EXPERIMENTAL BRAIN RESEARCH
- Motion sickness: more than nausea and vomiting
- (2014) James R. Lackner EXPERIMENTAL BRAIN RESEARCH
- The Significance of Interstitial Cells in Neurogastroenterology
- (2014) Peter J Blair et al. Journal of Neurogastroenterology and Motility
- The Relation Between Symptom Improvement and Gastric Emptying in the Treatment of Diabetic and Idiopathic Gastroparesis
- (2013) Pieter Janssen et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- I.V. APD421 (amisulpride) prevents postoperative nausea and vomiting: a randomized, double-blind, placebo-controlled, multicentre trial
- (2013) P. Kranke et al. BRITISH JOURNAL OF ANAESTHESIA
- Association of ABCB1 Polymorphisms with the Antiemetic Efficacy of Granisetron plus Dexamethasone in Breast Cancer Patients
- (2013) Daiki Tsuji et al. Drug Metabolism and Pharmacokinetics
- The relationship between gastric motility and nausea: Gastric prokinetic agents as treatments
- (2013) Gareth J. Sanger et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting
- (2013) Charles C. Horn et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Looking beyond 5-HT3 receptors: A review of the wider role of serotonin in the pharmacology of nausea and vomiting
- (2013) Kevin D. Johnston et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Opioid induced nausea and vomiting
- (2013) Howard S. Smith et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Molecular mechanisms of 5-HT3 and NK1 receptor antagonists in prevention of emesis
- (2013) Camilo Rojas et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Prognostic factors for chemotherapy induced nausea and vomiting
- (2013) David Warr EUROPEAN JOURNAL OF PHARMACOLOGY
- The cellular mechanisms of the antiemetic action of dexamethasone and related glucocorticoids against vomiting
- (2013) Chin-Chen Chu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Nausea and the quest for the perfect anti-emetic
- (2013) Paul L.R. Andrews et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Olanzapine for the prevention and treatment of chronic nausea and chemotherapy-induced nausea and vomiting
- (2013) Rudolph M. Navari EUROPEAN JOURNAL OF PHARMACOLOGY
- Mechanisms, causes, investigation and management of vomiting disorders in cats: a literature review
- (2013) Daniel J Batchelor et al. JOURNAL OF FELINE MEDICINE AND SURGERY
- Why Can’t Rodents Vomit? A Comparative Behavioral, Anatomical, and Physiological Study
- (2013) Charles C. Horn et al. PLoS One
- Evidence for the use of Levomepromazine for symptom control in the palliative care setting: a systematic review
- (2013) Isabel Dietz et al. BMC Palliative Care
- Pharmacology of antihistamines
- (2013) MartinK Church et al. INDIAN JOURNAL OF DERMATOLOGY
- Clinical Guideline: Management of Gastroparesis
- (2012) Michael Camilleri et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- The anti-nausea effects of CB1agonists are mediated by an action at the visceral insular cortex
- (2012) CL Limebeer et al. BRITISH JOURNAL OF PHARMACOLOGY
- Regional- and agonist-dependent facilitation of human neurogastrointestinal functions by motilin receptor agonists
- (2012) J Broad et al. BRITISH JOURNAL OF PHARMACOLOGY
- The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin
- (2012) John Broad et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Brain Circuitry Underlying the Temporal Evolution of Nausea in Humans
- (2012) V. Napadow et al. CEREBRAL CORTEX
- Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain
- (2012) David Borsook et al. DRUG DISCOVERY TODAY
- Pharmacological mechanisms of 5-HT3 and tachykinin NK1 receptor antagonism to prevent chemotherapy-induced nausea and vomiting
- (2012) Camilo Rojas et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Anti-emetic and emetic effects of erythromycin in Suncus murinus: Role of vagal nerve activation, gastric motility stimulation and motilin receptors
- (2012) Farideh A. Javid et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Abnormal Initiation and Conduction of Slow-Wave Activity in Gastroparesis, Defined by High-Resolution Electrical Mapping
- (2012) Gregory O'Grady et al. GASTROENTEROLOGY
- Predicting the emetic liability of novel chemical entities: a comparative study
- (2011) Nathalie Percie du Sert et al. BRITISH JOURNAL OF PHARMACOLOGY
- Does domperidone, a D2-antagonist alter gastric emptying rates and appetite sensations in healthy adults with high-fat meal? A block-randomised, single-blind placebo-controlled study
- (2011) O. Markey et al. IRISH JOURNAL OF MEDICAL SCIENCE
- Antiemetics for Chemotherapy-Induced Nausea and Vomiting Occurring Despite Prophylactic Antiemetic Therapy
- (2011) Jason M. Jones et al. JOURNAL OF PALLIATIVE MEDICINE
- Analysis of pacemaker activity in the human stomach
- (2011) Poong-Lyul Rhee et al. JOURNAL OF PHYSIOLOGY-LONDON
- Interactions of recombinant human histamine H1, H2, H3, and H4 receptors with 34 antidepressants and antipsychotics
- (2011) Heidrun Appl et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Application of Data Mining and Visualization Techniques for the Prediction of Drug-Induced Nausea in Man
- (2011) Joanna Parkinson et al. TOXICOLOGICAL SCIENCES
- The translational value of rodent gastrointestinal functions: a cautionary tale
- (2011) Gareth J. Sanger et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Psychiatric Co-morbidity and Efficacy of Mirtazapine Treatment in Young Subjects With Chronic or Cyclic Vomiting Syndromes: A Case Series
- (2011) Murat Coskun et al. Journal of Neurogastroenterology and Motility
- Biophysically Based Modeling of the Interstitial Cells of Cajal: Current Status and Future Perspectives
- (2011) Rachel Lees-Green et al. Frontiers in Physiology
- Regulation of nausea and vomiting by cannabinoids
- (2010) Linda A Parker et al. BRITISH JOURNAL OF PHARMACOLOGY
- Neuropharmacology of Vestibular System Disorders
- (2010) Enrique Soto et al. Current Neuropharmacology
- New Uses for Older Drugs: The Tales of Aspirin, Thalidomide, and Gabapentin
- (2010) Joseph I. Sirven MAYO CLINIC PROCEEDINGS
- Development and content validity of a gastroparesis cardinal symptom index daily diary
- (2009) D. A. REVICKI et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Opportunities for the replacement of animals in the study of nausea and vomiting
- (2009) AM Holmes et al. BRITISH JOURNAL OF PHARMACOLOGY
- Palonosetron triggers 5-HT3 receptor internalization and causes prolonged inhibition of receptor function
- (2009) Camilo Rojas et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Half a Century of Antidepressant Drugs
- (2009) Peter Fangmann et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Predicting new molecular targets for known drugs
- (2009) Michael J. Keiser et al. NATURE
- Translating 5-HT4receptor pharmacology
- (2009) g. j. sanger NEUROGASTROENTEROLOGY AND MOTILITY
- Characterisation of 5-HT3C, 5-HT3Dand 5-HT3Ereceptor subunits: evolution, distribution and function
- (2008) Joanna D. Holbrook et al. JOURNAL OF NEUROCHEMISTRY
- The in vitro pharmacological profile of TD-5108, a selective 5-HT4 receptor agonist with high intrinsic activity
- (2008) J. A. M. Smith et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Development of drugs for gastrointestinal motor disorders: translating science to clinical need
- (2008) g. j. sanger et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Undertreatment of nausea and other symptoms in hospitalized cancer patients
- (2008) Judi Greaves et al. SUPPORTIVE CARE IN CANCER
- H1 Antihistamines
- (2008) F. Estelle R. Simons et al. World Allergy Organization Journal
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