Article
Neurosciences
Hiroyuki Sakai, Takumi Harada, Stephen K. Larroque, Athena Demertzi, Tomoko Sugawara, Taeko Ito, Yoshiro Wada, Masaki Fukunaga, Norihiro Sadato, Steven Laureys
Summary: The study identified significant differences in functional connectivity and network centrality in the left parietal region of individuals highly susceptible to motion sickness. Additionally, an association was found between motion sickness susceptibility and white matter integrity in the left inferior fronto-occipital fasciculus.
HUMAN BRAIN MAPPING
(2022)
Article
Clinical Neurology
Riender Happee, Varun Kotian, Ksander N. De Winkel
Summary: This study combines a musculoskeletal neck model with models of sensory integration to examine the role of vestibular, visual, and muscle sensory cues in head-neck stabilization and their relationship to motion sickness. The results show the importance of sensory integration in postural stabilization and suggest that imprecise sensory integration may contribute to motion sickness.
FRONTIERS IN NEUROLOGY
(2023)
Article
Neurosciences
T. L. Lonner, A. R. Allred, L. Bonarrigo, A. Gopinath, K. Smith, V. Kravets, E. L. Groen, C. Oman, P. Dizio, B. D. Lawson, T. K. Clark
Summary: Entry motion sickness (EMS), which occurs when astronauts return to Earth after extended periods in microgravity, can be a problem. Anticholinergic pharmaceuticals like Meclizine are commonly used to prevent EMS, but they have side effects. This study examined the effectiveness of a non-pharmaceutical countermeasure using external visual cues to alleviate EMS symptoms. The results showed that providing motion-congruent visual cues through virtual reality significantly improved survival rates and comfort compared to a control group.
EXPERIMENTAL BRAIN RESEARCH
(2023)
Article
Clinical Neurology
Sebastian Wurthmann, Steffen Naegel, Miriam Roesner, Michael Nsaka, Armin Scheffler, Christoph Kleinschnitz, Dagny Holle, Mark Obermann
Summary: The study revealed that patients with vestibular migraine have lower motion perception thresholds and increased susceptibility to motion sickness in the interictal state, suggesting alterations in higher levels of vestibular processing.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Computer Science, Artificial Intelligence
Jiwon Kim, Seong-Min Lee, Hungsun Son, Taezoon Park
Summary: This study investigated the effects of motion and visual cues on simulator sickness in flight simulator training, finding that providing both cues can significantly decrease sickness severity, particularly in reducing nausea and disorientation.
EXPERT SYSTEMS WITH APPLICATIONS
(2023)
Article
Psychology, Biological
Sigbjorn Litleskare
Summary: Virtual reality can cause cybersickness, with deteriorations in postural stability possibly predicting or objectively measuring the sickness, but individual differences and overlapping symptoms complicate the relationship.
PHYSIOLOGY & BEHAVIOR
(2021)
Article
Computer Science, Cybernetics
Stephen Palmisano, Robert S. Allison, Rodney G. Davies, Peter Wagner, Juno Kim
Summary: In this study, the impact of display lag on the differences between virtual and physical head pose in VR was examined, and the predictive value of DVP on cybersickness was investigated. The results showed that different types of added lag generated similar levels of cybersickness, and participants' DVP reliably predicted the severity of cybersickness.
INTERNATIONAL JOURNAL OF HUMAN-COMPUTER INTERACTION
(2023)
Article
Computer Science, Interdisciplinary Applications
Stephen Palmisano, Robert S. Allison, Joel Teixeira, Juno Kim
Summary: During HMD-based VR, differences in virtual and physical head pose (DVP) caused by head movements and display lag contribute to cybersickness. This study measured cybersickness and estimated DVP under different levels of display lag. The results showed that the severity of cybersickness increased with the amplitude and variability of DVP, supporting the DVP hypothesis.
Article
Computer Science, Cybernetics
Tugrul Irmak, Daan M. Pool, Ksander N. de Winkel, Riender Happee
Summary: The ability of current perception models to predict motion sickness is limited, and further research is needed to resolve the ambiguous aspects of the models. Active estimation of gravity and the influence of semicircular canals on the somatogravic effect have been identified as potential mechanisms for improving sickness prediction.
BIOLOGICAL CYBERNETICS
(2023)
Article
Behavioral Sciences
David Lorincz, Hannah R. Drury, Doug W. Smith, Rebecca Lim, Alan M. Brichta
Summary: The study examined the relationship between motion sickness and brainstem efferent vestibular nucleus (EVN) neurons, showing that young adult WT and transgenic mice exhibit motion sickness symptoms and activation of EVN neurons, while aged WT mice do not show symptoms or changes in c-Fos expression when exposed to the same provocative stimulus.
BRAIN AND BEHAVIOR
(2023)
Article
Neurosciences
Danyang Meng, Xuyou Zhou, Tianye Hu, Jialian Zheng, Tingyu Jin, Han Gao, Jin Hu
Summary: This study collected clinical data from vestibular migraine (VM) patients and healthy control populations to analyze the clinical characteristics of VM patients, focusing on the history of motion sickness. The results showed that VM patients had a higher prevalence of motion sickness history, and women and older individuals were more likely to have VM. The history of motion sickness may serve as a potential suggestive factor for the diagnosis of VM.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Clinical Neurology
Jamie M. Bogle, Eduardo Benarroch, Paola Sandroni
Summary: This review summarizes the role of vestibular-autonomic interactions in various clinical presentations of disorders and discusses recent advancements in understanding the underlying mechanisms. The insular cortex has been identified as a key cortical site for vestibular sensation and autonomic integration and modulation.
CURRENT OPINION IN NEUROLOGY
(2022)
Article
Clinical Neurology
Nese Celebisoy, Aysin Kisabay Ak, Ceyla Atac, Hueseyin Nezih Ozdemir, Figen Gokcay, Gulsum Saruhan Durmaz, Dilek Top Karti, Hulya Ertasoglu Toydemir, Vildan Yayla, Ilksen Colpak Isikay, Irem Erkent, Ayseguel Seyma Saritas, Pinar Ozcelik, Gulden Akdal, Sebnem Bicakci, Eylem Ozaydin Goksu, Feray Gulec Uyaroglu
Summary: This retrospective study aimed to compare the differences between migraine patients without any vestibular symptoms (MwoV) and vestibular migraine patients (VM) and to identify the specific clinical features associated with VM. The study found that migraine with aura was more frequent in MwoV patients, while VM patients had longer migraine headache years and higher headache intensity, accompanied by symptoms such as aural fullness/tinnitus. VM patients also reported a higher prevalence of menopause and motion sickness history. Logistic regression analysis revealed that long-standing history of severe migraine attacks, aural fullness/tinnitus, presence of menopause, and previous motion sickness history were the distinguishing clinical features of VM patients.
JOURNAL OF NEUROLOGY
(2023)
Article
Behavioral Sciences
Monica Alcantara-Thome, Jose A. Miguel-Puga, Kathrine Jauregui-Renaud
Summary: The study found that anxiety/depression and adult motion sickness susceptibility can influence the ability to update orientation after passive rotation, with no significant impact from age. Interaction between the use of spectacles, sleep quality, and sex also affects the estimation error of orientation.
FRONTIERS IN INTEGRATIVE NEUROSCIENCE
(2021)
Article
Clinical Neurology
Cong-cong Li, Zhuo-ru Zhang, Yu-hui Liu, Tao Zhang, Xu-tao Zhang, Han Wang, Xiao-cheng Wang
Summary: This study successfully developed an objective multi-dimensional susceptibility assessment model for motion sickness (MS) based on machine learning. The model can accurately assess the susceptibility of individuals to MS and provide valuable references for transportation and entertainment choices, as well as public health and safety.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Alexander A. Tarnutzer, K. P. Weber, B. Schuknecht, D. Straumann, S. Marti, G. Bertolini
JOURNAL OF NEUROLOGY
(2015)
Article
Neurosciences
Paolo Colagiorgio, Giovanni Bertolini, Christopher J. Bockisch, Dominik Straumann, Stefano Ramat
JOURNAL OF NEUROPHYSIOLOGY
(2015)
Editorial Material
Behavioral Sciences
Lucian M. Macrea, Gianluca Macauda, Giovanni Bertolini, Dominik Straumann, Peter Brugger, Konrad Maurer, Antonella Palla, Bigna Lenggenhager
Article
Neurosciences
Bart B. G. T. Alberts, Luc P. J. Selen, Giovanni Bertolini, Dominik Straumann, W. Pieter Medendorp, Alexander A. Tarnutzer
JOURNAL OF NEUROPHYSIOLOGY
(2016)
Article
Clinical Neurology
Fausto Romano, Nicoletta Caramia, Dominik Straumann, Eugene Nalivaiko, Giovanni Bertolini
JOURNAL OF NEUROLOGY
(2017)
Article
Neurosciences
Bryan K. Ward, Christopher J. Bockisch, Nicoletta Caramia, Giovanni Bertolini, Alexander Andrea Tarnutzer
JOURNAL OF NEUROPHYSIOLOGY
(2017)
Article
Neurosciences
Fausto Romano, Alexander A. Tarnutzer, Dominik Straumann, Stefano Ramat, Giovanni Bertolini
JOURNAL OF PHYSIOLOGY-LONDON
(2017)
Article
Clinical Neurology
Giovanni Bertolini, Meek Angela Durmaz, Kim Ferrari, Alexander Kueffer, Charlotte Lambert, Dominik Straumann
FRONTIERS IN NEUROLOGY
(2017)
Article
Neurosciences
Luca Rinaldi, Giovanni Bertolini, Christopher J. Bockisch, Angelo Maravita, Luisa Girelli, Peter Brugger
BRAIN AND COGNITION
(2018)
Article
Clinical Neurology
Fausto Romano, Giovanni Bertolini, Daniel Agostino, Dominik Straumann, Stefano Ramat, Nina Feddermann-Demont
FRONTIERS IN NEUROLOGY
(2019)
Article
Multidisciplinary Sciences
Rosa M. S. Visscher, Nina Feddermann-Demont, Fausto Romano, Dominik Straumann, Giovanni Bertolini
Article
Clinical Neurology
Viviana Mucci, Cornelia Meier, Mario Bizzini, Fausto Romano, Daniel Agostino, Alessandra Ventura, Giovanni Bertolini, Nina Feddermann-Demont
FRONTIERS IN NEUROLOGY
(2019)
Article
Neurosciences
Stefan Yu Boegli, Dominik Straumann, Bernhard Schuknecht, Giovanni Bertolini, Alexander A. Tarnutzer
Summary: The study found that during sustained eccentric gaze, the eye drift velocity of gaze-evoked nystagmus decreases gradually, followed by a uniform change in eye drift. These two movements are highly correlated, suggesting a potential diagnostic marker for cerebellar degeneration.
Article
Ophthalmology
Stefan Yu Boegli, Maresa Afthinos, Giovanni Bertolini, Dominik Straumann, Melody Ying-Yu Huang
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2016)