Journal
EUROPEAN JOURNAL OF PHARMACOLOGY
Volume 722, Issue -, Pages 67-78Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ejphar.2013.09.074
Keywords
Nausea; Vomiting; Opioids; Olanzapine; NK-1; Antagonists; Moxduo; Tapentadol
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Opioids are broad spectrum analgesics that are an integral part of the therapeutic armamentarium to combat pain in the palliative care population. Unfortunately, among the adverse effects of opioids that may be experienced along with analgesia is nausea, vomiting, and/or retching. Although it is conceivable that in the future, using combination agents (opioids combined with agents which may nullify emetic effects), currently nausea/vomiting remains a significant issue for certain patients. However, there exists potential current strategies that may be useful in efforts to diminish the frequency and/or intensity of opioid-induced nausea/vomiting (OINV). Published by Elsevier B.V.
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