ABC transporters in CSCs membranes as a novel target for treating tumor relapse
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
ABC transporters in CSCs membranes as a novel target for treating tumor relapse
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 5, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2014-07-10
DOI
10.3389/fphar.2014.00163
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells
- (2015) Parvinder Hothi et al. Oncotarget
- SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity
- (2014) Giulia Nesi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Monoclonal antibodies against human cancer stem cells
- (2014) Cord Naujokat Immunotherapy
- Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
- (2013) Eva Wessel Stratford et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Activity–lipophilicity relationship studies on P-gp ligands designed as simplified tariquidar bulky fragments
- (2013) Marialessandra Contino et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Potent and selective tariquidar bioisosters as potential PET radiotracers for imaging P-gp
- (2013) Marialessandra Contino et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells
- (2013) Andrew R. Germain et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Aptamer Identification of Brain Tumor-Initiating Cells
- (2013) Y. Kim et al. CANCER RESEARCH
- Regulation of Ovarian Cancer Stem Cells or Tumor-Initiating Cells
- (2013) Mi Kwon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
- (2013) Monica Bostad et al. JOURNAL OF CONTROLLED RELEASE
- The Development of Highly Potent Inhibitors for Porcupine
- (2013) Xiaolei Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Expression and prognostic value of tumor stem cell markers ALDH1 and CD133 in colorectal carcinoma
- (2013) FEI ZHOU et al. Oncology Letters
- Isolation of side population cells from endometrial cancer cells using a violet laser diode
- (2013) Satoshi Tomiyasu et al. Human Cell
- Isolation, identification and expression of specific human CD133 antibodies
- (2013) Jing Xia et al. Scientific Reports
- Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia
- (2013) Christopher P. Guise et al. Chinese Journal of Cancer
- The Role of Bystander Effects in the Antitumor Activity of the Hypoxia-Activated Prodrug PR-104
- (2013) Annika Foehrenbacher et al. Frontiers in Oncology
- Naphthalenyl derivatives for hitting P-gp/MRP1/BCRP transporters
- (2012) Nicola A. Colabufo et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress
- (2012) K Ketola et al. BRITISH JOURNAL OF CANCER
- Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells
- (2012) P Liu et al. BRITISH JOURNAL OF CANCER
- EO9 (Apaziquone): from the clinic to the laboratory and back again
- (2012) Roger M Phillips et al. BRITISH JOURNAL OF PHARMACOLOGY
- Repeated cisplatin treatment can lead to a multiresistant tumor cell population with stem cell features and sensitivity to 3-bromopyruvate
- (2012) My Wintzell et al. CANCER BIOLOGY & THERAPY
- A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice
- (2012) J. Waaler et al. CANCER RESEARCH
- Wnt/β-Catenin Signaling and Disease
- (2012) Hans Clevers et al. CELL
- On the Reaction Mechanism of Tirapazamine Reduction Chemistry: Unimolecular N–OH Homolysis, Stepwise Dehydration, or Triazene Ring-Opening
- (2012) Jian Yin et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Metformin targets ovarian cancer stem cells in vitro and in vivo
- (2012) Jessica J. Shank et al. GYNECOLOGIC ONCOLOGY
- Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells
- (2012) Prajakta S. Oak et al. INTERNATIONAL JOURNAL OF CANCER
- The Implications of Cancer Stem Cells for Cancer Therapy
- (2012) Wenjing Jiang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The evolving concept of cancer and metastasis stem cells
- (2012) Irène Baccelli et al. JOURNAL OF CELL BIOLOGY
- Selective killing of cancer stem cells by a novel dual-targeting strategy
- (2012) Deshuai Lou et al. MEDICAL HYPOTHESES
- Effects of Salinomycin on Cancer Stem Cell in Human Lung Adenocarcinoma A549 Cells
- (2012) Yi Wang Medicinal Chemistry
- Growth Inhibition of Ovarian Tumor-Initiating Cells by Niclosamide
- (2012) Y.-T. Yo et al. MOLECULAR CANCER THERAPEUTICS
- Drug screening study using glioma stem-like cells
- (2012) XING FENG et al. Molecular Medicine Reports
- WIKI4, a Novel Inhibitor of Tankyrase and Wnt/ß-Catenin Signaling
- (2012) Richard G. James et al. PLoS One
- Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy
- (2012) S. M. McAuliffe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of inhibitors of ovarian cancer stem-like cells by high-throughput screening
- (2012) Roman Mezencev et al. Journal of Ovarian Research
- Salinomycin Selectively Targets ‘CD133+’ Cell Subpopulations and Decreases Malignant Traits in Colorectal Cancer Lines
- (2011) Tao-Tao Dong et al. ANNALS OF SURGICAL ONCOLOGY
- Salinomycin can effectively kill ALDHhigh stem-like cells on gastric cancer
- (2011) Qiao Ming Zhi et al. BIOMEDICINE & PHARMACOTHERAPY
- Salinomycin inhibits osteosarcoma by targeting its tumor stem cells
- (2011) Qing-Lian Tang et al. CANCER LETTERS
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas
- (2011) Devraj Basu et al. CELL CYCLE
- A New Hypoxia Inducible Factor-2 Inhibitory Pyrrolinone Alkaloid from Roots and Stems of Piper sarmentosum
- (2011) Heidi Rose Bokesch et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer’s Disease
- (2011) Marialessandra Contino et al. ChemMedChem
- Multidrug Efflux Pumps and Cancer Stem Cells: Insights Into Multidrug Resistance and Therapeutic Development
- (2011) K Moitra et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Induction of apoptosis by metformin in epithelial ovarian cancer: Involvement of the Bcl-2 family proteins
- (2011) Amber Yasmeen et al. GYNECOLOGIC ONCOLOGY
- The impact of novel retinoids in combination with platinum chemotherapy on ovarian cancer stem cells
- (2011) Jenny M. Whitworth et al. GYNECOLOGIC ONCOLOGY
- The cancer stem cell niche-there goes the neighborhood?
- (2011) Stephanie M. Cabarcas et al. INTERNATIONAL JOURNAL OF CANCER
- Targeting Tumor-Initiating Cancer Cells with dCD133KDEL Shows Impressive Tumor Reductions in a Xenotransplant Model of Human Head and Neck Cancer
- (2011) N. N. Waldron et al. MOLECULAR CANCER THERAPEUTICS
- Targeting the Mitochondria Activates Two Independent Cell Death Pathways in Ovarian Cancer Stem Cells
- (2011) A. B. Alvero et al. MOLECULAR CANCER THERAPEUTICS
- Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302
- (2011) F. Meng et al. MOLECULAR CANCER THERAPEUTICS
- The cancer stem cell: premises, promises and challenges
- (2011) Hans Clevers NATURE MEDICINE
- Antibody drug conjugates — Trojan horses in the war on cancer
- (2011) U. Iyer et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Phenotypic Heterogeneity of Breast Cancer Stem Cells
- (2011) Aurelio Lorico et al. Journal of Oncology
- Regulation of Inflammation by the NF-κB Pathway in Ovarian Cancer Stem Cells
- (2010) Aliza L. Leizer et al. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells
- (2010) Dominik Fuchs et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Wnt/β-catenin signaling regulates cancer stem cells in lung cancer A549 cells
- (2010) Ying Teng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibiting NF-κB activation by small molecules as a therapeutic strategy
- (2010) Subash C. Gupta et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor
- (2010) Roberta Riccioni et al. BLOOD CELLS MOLECULES AND DISEASES
- β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells
- (2010) Jenny Yeung et al. CANCER CELL
- Aldehyde Dehydrogenase 1 A1-Positive Cell Population Is Enriched in Tumor-Initiating Cells and Associated with Progression of Bladder Cancer
- (2010) Y. Su et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- The Canonical NF- B Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
- (2010) M. Liu et al. CANCER RESEARCH
- Pharmacokinetic/Pharmacodynamic Modeling Identifies SN30000 and SN29751 as Tirapazamine Analogues with Improved Tissue Penetration and Hypoxic Cell Killing in Tumors
- (2010) K. O. Hicks et al. CLINICAL CANCER RESEARCH
- Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens
- (2010) Kristen M. Smith et al. EMBO Molecular Medicine
- Multicellular tumor spheroids: An underestimated tool is catching up again
- (2010) Franziska Hirschhaeuser et al. JOURNAL OF BIOTECHNOLOGY
- Tirapazamine, Cisplatin, and Radiation Versus Cisplatin and Radiation for Advanced Squamous Cell Carcinoma of the Head and Neck (TROG 02.02, HeadSTART): A Phase III Trial of the Trans-Tasman Radiation Oncology Group
- (2010) Danny Rischin et al. JOURNAL OF CLINICAL ONCOLOGY
- Characterization of Radicals Formed Following Enzymatic Reduction of 3-Substituted Analogues of the Hypoxia-Selective Cytotoxin 3-Amino-1,2,4-Benzotriazine 1,4-Dioxide (Tirapazamine)
- (2010) Sujata S. Shinde et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics
- (2010) Anna Maria Calcagno et al. JNCI-Journal of the National Cancer Institute
- Targeting Aldehyde Dehydrogenase Cancer Stem Cells in Ovarian Cancer
- (2010) C. N. Landen et al. MOLECULAR CANCER THERAPEUTICS
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- Development of DNA aptamers using Cell-SELEX
- (2010) Kwame Sefah et al. Nature Protocols
- Targeting cancer stem cells by inhibiting Wnt, Notch and Hedgehog pathways
- (2010) Naoko Takebe et al. Nature Reviews Clinical Oncology
- CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells
- (2010) M-Q Gao et al. ONCOGENE
- 8-bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK
- (2010) Xiao-Hong Yang WORLD JOURNAL OF GASTROENTEROLOGY
- Reversible Cell-Specific Drug Delivery with Aptamer-Functionalized Liposomes
- (2009) Zehui Cao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- DNA Cross-Links in Human Tumor Cells Exposed to the Prodrug PR-104A: Relationships to Hypoxia, Bioreductive Metabolism, and Cytotoxicity
- (2009) R. S. Singleton et al. CANCER RESEARCH
- Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway
- (2009) Z. Wang et al. CANCER RESEARCH
- Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis
- (2009) E. H. Huang et al. CANCER RESEARCH
- Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
- (2009) H. A. Hirsch et al. CANCER RESEARCH
- Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells
- (2009) Masayoshi Kobune et al. CANCER SCIENCE
- Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens
- (2009) Steven M. Pollard et al. Cell Stem Cell
- PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells
- (2009) Anne-Marie Bleau et al. Cell Stem Cell
- Multi-Drug-Resistance-Reverting Agents: 2-Aryloxazole and 2-Arylthiazole Derivatives as Potent BCRP or MRP1 Inhibitors
- (2009) Nicola A. Colabufo et al. ChemMedChem
- Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer
- (2009) E. Charafe-Jauffret et al. CLINICAL CANCER RESEARCH
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- ABCG2: the key to chemoresistance in cancer stem cells?
- (2009) Yi An et al. Expert Opinion on Drug Metabolism & Toxicology
- Perspectives of P-Glycoprotein Modulating Agents in Oncology and Neurodegenerative Diseases: Pharmaceutical, Biological, and Diagnostic Potentials
- (2009) Nicola Antonio Colabufo et al. JOURNAL OF MEDICINAL CHEMISTRY
- ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients’ outcome
- (2009) Ting Li et al. LABORATORY INVESTIGATION
- Aldehyde Dehydrogenase 1 Is a Tumor Stem Cell-Associated Marker in Lung Cancer
- (2009) F. Jiang et al. MOLECULAR CANCER RESEARCH
- Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
- (2009) Shih-Min A. Huang et al. NATURE
- Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
- (2009) Chen Zhao et al. NATURE
- Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
- (2009) Baozhi Chen et al. Nature Chemical Biology
- Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44
- (2009) Shigeo Takaishi et al. STEM CELLS
- Regulation of Mammary Stem/Progenitor Cells by PTEN/Akt/β-Catenin Signaling
- (2009) Hasan Korkaya et al. PLOS BIOLOGY
- 4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators
- (2008) Nicola Antonio Colabufo et al. BIOORGANIC & MEDICINAL CHEMISTRY
- CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers
- (2008) L M Smith et al. BRITISH JOURNAL OF CANCER
- Targeting CD24 for Treatment of Colorectal and Pancreatic Cancer by Monoclonal Antibodies or Small Interfering RNA
- (2008) E. Sagiv et al. CANCER RESEARCH
- Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors
- (2008) S. Zhang et al. CANCER RESEARCH
- PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
- (2008) D. Hambardzumyan et al. GENES & DEVELOPMENT
- Hedgehog: functions and mechanisms
- (2008) M. Varjosalo et al. GENES & DEVELOPMENT
- In vitro metformin anti-neoplastic activity in epithelial ovarian cancer
- (2008) Walter H. Gotlieb et al. GYNECOLOGIC ONCOLOGY
- Cancer Stem Cells: A Step Toward the Cure
- (2008) Bruce M. Boman et al. JOURNAL OF CLINICAL ONCOLOGY
- An efficient method for derivation and propagation of glioblastoma cell lines that conserves the molecular profile of their original tumours
- (2008) Talal M. Fael Al-Mayhani et al. JOURNAL OF NEUROSCIENCE METHODS
- CD133 Is a Marker of Bioenergetic Stress in Human Glioma
- (2008) Corinne E. Griguer et al. PLoS One
- The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
- (2008) A. Dubrovska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aldehyde Dehydrogenase as a Marker for Stem Cells
- (2008) Jan Moreb Current Stem Cell Research & Therapy
- Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives
- (2007) Nicola Antonio Colabufo et al. BIOORGANIC & MEDICINAL CHEMISTRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started