WIKI4, a Novel Inhibitor of Tankyrase and Wnt/ß-Catenin Signaling

A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice

(2012) J. Waaler et al.   CANCER RESEARCH

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Visualization and exploration of Tcf/Lef function using a highly responsive Wnt/β-catenin signaling-reporter transgenic zebrafish

(2012) Nobuyuki Shimizu et al.   DEVELOPMENTAL BIOLOGY

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains

(2012) Enrico Moro et al.   DEVELOPMENTAL BIOLOGY

Canonical Wnt Signaling Dynamically Controls Multiple Stem Cell Fate Decisions during Vertebrate Body Formation

(2012) Benjamin L. Martin et al.   DEVELOPMENTAL CELL

Wnt/ -catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

(2012) K. C. Davidson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt/ -Catenin Signaling and AXIN1 Regulate Apoptosis Triggered by Inhibition of the Mutant Kinase BRAFV600E in Human Melanoma

(2012) T. L. Biechele et al.   Science Signaling

Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo

(2011) Satomi S. Tanaka et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Dysregulation of Wnt/β-Catenin Signaling in Gastrointestinal Cancers

(2011) Bryan D. White et al.   GASTROENTEROLOGY

A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3

(2011) H. K. Bone et al.   JOURNAL OF CELL SCIENCE

RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling

(2011) Yue Zhang et al.   NATURE CELL BIOLOGY

Ubiquitin Ligase RNF146 Regulates Tankyrase and Axin to Promote Wnt Signaling

(2011) Marinella G. Callow et al.   PLoS One

Chemical-Genetic Screen Identifies Riluzole as an Enhancer of Wnt/β-catenin Signaling in Melanoma

(2010) Travis L. Biechele et al.   CHEMISTRY & BIOLOGY

Aurora kinase A is a target of Wnt/ -catenin involved in multiple myeloma disease progression

(2009) J. Dutta-Simmons et al.   BLOOD

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma

(2008) P. Gelebart et al.   BLOOD

New Regulators of Wnt/ -Catenin Signaling Revealed by Integrative Molecular Screening

(2008) M. B. Major et al.   Science Signaling