Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells

Salinomycin Selectively Targets ‘CD133+’ Cell Subpopulations and Decreases Malignant Traits in Colorectal Cancer Lines

(2011) Tao-Tao Dong et al.   ANNALS OF SURGICAL ONCOLOGY

Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3

(2010) Li Ma et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells

(2010) Dominik Fuchs et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein

(2010) Ju-Hwa Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

ErbB2 requires integrin  5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells

(2010) K. K. Haenssen et al.   JOURNAL OF CELL SCIENCE

Activated Phosphoinositide 3-Kinase/AKT Signaling Confers Resistance to Trastuzumab but not Lapatinib

(2010) N. A. O'Brien et al.   MOLECULAR CANCER THERAPEUTICS

Immunoselection of Breast and Ovarian Cancer Cells with Trastuzumab and Natural Killer Cells: Selective Escape of CD44high/CD24low/HER2low Breast Cancer Stem Cells

(2009) F. Reim et al.   CANCER RESEARCH

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

(2009) Hongyan Zhou et al.   Cell Stem Cell

Tumor-Initiating Cells of HER2-Positive Carcinoma Cell Lines Express the Highest Oncoprotein Levels and Are Sensitive to Trastuzumab

(2009) A. Magnifico et al.   CLINICAL CANCER RESEARCH

Resistance to Trastuzumab in Breast Cancer

(2009) P. R. Pohlmann et al.   CLINICAL CANCER RESEARCH

The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB453 breast cancer cells

(2009) A Roidl et al.   ONCOGENE

Myc Is a Metastasis Gene for Non-Small-Cell Lung Cancer

(2009) Ulf R. Rapp et al.   PLoS One

Breast cancer chemoresistance: Emerging importance of cancer stem cells

(2009) Suebwong Chuthapisith et al.   SURGICAL ONCOLOGY-OXFORD

Mechanisms and strategies to overcome chemotherapy resistance in metastatic breast cancer

(2008) Helen M. Coley   CANCER TREATMENT REVIEWS

Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments

(2008) Mark A. LaBarge et al.   Integrative Biology

High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability

(2008) Alysha K. Croker et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

“Stemness” Genomics Law Governs Clinical Behavior of Human Cancer: Implications for Decision Making in Disease Management

(2008) Gennadi V. Glinsky   JOURNAL OF CLINICAL ONCOLOGY

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion

(2008) H Korkaya et al.   ONCOGENE

Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab

(2008) M Pickl et al.   ONCOGENE

ABC multidrug transporters: structure, function and role in chemoresistance

(2007) Frances J Sharom   PHARMACOGENOMICS