Hydrogel Scaffolds: Towards Restitution of Ischemic Stroke-Injured Brain

A Review on Recent Advances in Stabilizing Peptides/Proteins upon Fabrication in Hydrogels from Biodegradable Polymers

(2018) Faisal Raza et al.   Pharmaceutics

Comparative study of porous hydroxyapatite/chitosan and whitlockite/chitosan scaffolds for bone regeneration in calvarial defects

(2017) Ding Zhou et al.   International Journal of Nanomedicine

Neural stem cell transplantation in ischemic stroke: A role for preconditioning and cellular engineering

(2017) Joshua D Bernstock et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

3D visualization and quantification of microvessels in the whole ischemic mouse brain using solvent-based clearing and light sheet microscopy

(2017) Erlen Lugo-Hernandez et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Nerve Guidance by a Decellularized Fibroblast Extracellular Matrix

(2017) Greg M. Harris et al.   MATRIX BIOLOGY

Endogenous regeneration: Engineering growth factors for stroke

(2017) Su Jing Chan et al.   NEUROCHEMISTRY INTERNATIONAL

Interpenetrating Conducting Hydrogel Materials for Neural Interfacing Electrodes

(2017) Josef Goding et al.   Advanced Healthcare Materials

Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke

(2017) Fahad A. Somaa et al.   Cell Reports

Preparation and Characterization of Highly Aligned Carbon Nanotubes/Polyacrylonitrile Composite Nanofibers

(2017) Yanhua Song et al.   Polymers

Chondroitin Sulfate Glycosaminoglycan Matrices Promote Neural Stem Cell Maintenance and Neuroprotection Post-Traumatic Brain Injury

(2017) Martha I. Betancur et al.   ACS Biomaterials-Science & Engineering

Chondroitin Sulfate Glycosaminoglycan Matrices Promote Neural Stem Cell Maintenance and Neuroprotection Post-Traumatic Brain Injury

(2017) Martha I. Betancur et al.   ACS Biomaterials Science & Engineering

β1 integrin signaling promotes neuronal migration along vascular scaffolds in the post-stroke brain

(2017) Teppei Fujioka et al.   EBioMedicine

Using NGF heparin-poloxamer thermosensitive hydrogels to enhance the nerve regeneration for spinal cord injury

(2016) Ying-Zheng Zhao et al.   Acta Biomaterialia

Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering

(2016) Janahan Arulmoli et al.   Acta Biomaterialia

Transplantation of RADA16-BDNF peptide scaffold with human umbilical cord mesenchymal stem cells forced with CXCR4 and activated astrocytes for repair of traumatic brain injury

(2016) W. Shi et al.   Acta Biomaterialia

Engineering EMT using 3D micro-scaffold to promote hepatic functions for drug hepatotoxicity evaluation

(2016) Jingyu Wang et al.   BIOMATERIALS

A new three dimensional biomimetic hydrogel to deliver factors secreted by human mesenchymal stem cells in spinal cord injury

(2016) Ilaria Caron et al.   BIOMATERIALS

Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain

(2016) Pouria Moshayedi et al.   BIOMATERIALS

A drug delivery hydrogel system based on activin B for Parkinson's disease

(2016) Juan Li et al.   BIOMATERIALS

Hydrogels for brain repair after stroke: an emerging treatment option

(2016) Lina Ratiba Nih et al.   CURRENT OPINION IN BIOTECHNOLOGY

Neurite extension and neuronal differentiation of human induced pluripotent stem cell derived neural stem cells on polyethylene glycol hydrogels containing a continuous Young's Modulus gradient

(2016) Matthew C. Mosley et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Multiparametric magnetic resonance imaging including oxygenation mapping of experimental ischaemic stroke

(2016) Ligia Simões Braga Boisserand et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Hydrogel-delivered brain-derived neurotrophic factor promotes tissue repair and recovery after stroke

(2016) Douglas J Cook et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lauroyl-gemcitabine-loaded lipid nanocapsule hydrogel for the treatment of glioblastoma

(2016) C. Bastiancich et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases

(2016) Cláudia Saraiva et al.   JOURNAL OF CONTROLLED RELEASE

Modeling cell shape and dynamics on micropatterns

(2016) Philipp J. Albert et al.   Cell Adhesion & Migration

Biomaterial Applications in Cell-Based Therapy in Experimental Stroke

(2016) Ligia S. B. Boisserand et al.   Stem Cells International

Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease

(2016) Valentina Cappello et al.   Scientific Reports

A Neuroprotective Sericin Hydrogel As an Effective Neuronal Cell Carrier for the Repair of Ischemic Stroke

(2015) Zheng Wang et al.   ACS Applied Materials & Interfaces

Enhancing neural stem cell response to SDF-1α gradients through hyaluronic acid-laminin hydrogels

(2015) C.P. Addington et al.   BIOMATERIALS

Enhancing neurogenesis and angiogenesis with target delivery of stromal cell derived factor-1α using a dual ionic pH-sensitive copolymer

(2015) Dong Hee Kim et al.   BIOMATERIALS

Molecular Design of Light-Responsive Hydrogels, For in Situ Generation of Fast and Reversible Valves for Microfluidic Applications

(2015) Jeroen ter Schiphorst et al.   CHEMISTRY OF MATERIALS

Opportunities and Challenges: Stem Cell-Based Therapy for the Treatment of Ischemic Stroke

(2015) Yao-Hui Tang et al.   CNS Neuroscience & Therapeutics

Biomimetic Synthetic Self-Assembled Hydrogels for Cell Transplantation

(2015) Daniela Barros et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Scaffolds and cells for tissue regeneration: different scaffold pore sizes—different cell effects

(2015) Ieva Bružauskaitė et al.   CYTOTECHNOLOGY

Current developments in cell- and biomaterial-based approaches for stroke repair

(2015) Pavla Jendelová et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Injectable biopolymer based hydrogels for drug delivery applications

(2015) Sadia Atta et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Circumventing the blood–brain barrier: Local delivery of cyclosporin A stimulates stem cells in stroke-injured rat brain

(2015) Anup Tuladhar et al.   JOURNAL OF CONTROLLED RELEASE

Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma

(2015) Thibaut Fourniols et al.   JOURNAL OF CONTROLLED RELEASE

Click-crosslinked injectable hyaluronic acid hydrogel is safe and biocompatible in the intrathecal space for ultimate use in regenerative strategies of the injured spinal cord

(2015) T. Führmann et al.   METHODS

Present and future challenges of induced pluripotent stem cells

(2015) Mari Ohnuki et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Tissue-Engineered Breast Reconstruction with Brava-Assisted Fat Grafting

(2015) Roger K. Khouri et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Delivering Heparin-Binding Insulin-Like Growth Factor 1 with Self-Assembling Peptide Hydrogels

(2015) Emily M. Florine et al.   TISSUE ENGINEERING PART A

Hydrogels as scaffolds and delivery systems to enhance axonal regeneration after injuries

(2015) Oscar A. Carballo-Molina et al.   Frontiers in Cellular Neuroscience

Physical, Spatial, and Molecular Aspects of Extracellular Matrix ofIn VivoNiches and Artificial Scaffolds Relevant to Stem Cells Research

(2015) Maria Akhmanova et al.   Stem Cells International

Control of stem cell fate by engineering their micro and nanoenvironment

(2015) Michelle F Griffin   World Journal of Stem Cells

Delivery of iPS-NPCs to the Stroke Cavity within a Hyaluronic Acid Matrix Promotes the Differentiation of Transplanted Cells

(2014) Jonathan Lam et al.   ADVANCED FUNCTIONAL MATERIALS

A Perspective on the Clinical Translation of Scaffolds for Tissue Engineering

(2014) Matthew J. Webber et al.   ANNALS OF BIOMEDICAL ENGINEERING

Intermittent electrical stimuli for guidance of human mesenchymal stem cell lineage commitment towards neural-like cells on electroconductive substrates

(2014) Greeshma Thrivikraman et al.   BIOMATERIALS

pH sensitive N-succinyl chitosan grafted polyacrylamide hydrogel for oral insulin delivery

(2014) Piyasi Mukhopadhyay et al.   CARBOHYDRATE POLYMERS

Patterned and functionalized nanofiber scaffolds in three-dimensional hydrogel constructs enhance neurite outgrowth and directional control

(2014) Richard J McMurtrey   Journal of Neural Engineering

Meta analysis of olfactory ensheathing cell transplantation promoting functional recovery of motor nerves in rats with complete spinal cord transection

(2014) Liangbi Xiang et al.   Neural Regeneration Research

Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification

(2014) S. Musah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogel Design of Experiments Methodology to Optimize Hydrogel for iPSC-NPC Culture

(2014) Jonathan Lam et al.   Advanced Healthcare Materials

Tunable drug-loading capability of chitosan hydrogels with varied network architectures

(2013) Giuseppe Tronci et al.   Acta Biomaterialia

The effect of synthetic oxygen carrier-enriched fibrin hydrogel on Schwann cells under hypoxia condition in vitro

(2013) Teng Ma et al.   BIOMATERIALS

Transplantation of human mesenchymal stem cells loaded on collagen scaffolds for the treatment of traumatic brain injury in rats

(2013) Jian Guan et al.   BIOMATERIALS

The survival of engrafted neural stem cells within hyaluronic acid hydrogels

(2013) Yajie Liang et al.   BIOMATERIALS

Electrospun gelatin scaffolds incorporating rat decellularized brain extracellular matrix for neural tissue engineering

(2013) Silvia Baiguera et al.   BIOMATERIALS

Enhancing neuronal growth from human endometrial stem cells derived neuron-like cells in three-dimensional fibrin gel for nerve tissue engineering

(2013) Mona Navaei-Nigjeh et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke

(2013) Matthew J. Caicco et al.   JOURNAL OF CONTROLLED RELEASE

Bioengineered sequential growth factor delivery stimulates brain tissue regeneration after stroke

(2013) Yuanfei Wang et al.   JOURNAL OF CONTROLLED RELEASE

Zwitterionic hydrogels implanted in mice resist the foreign-body reaction

(2013) Lei Zhang et al.   NATURE BIOTECHNOLOGY

Regenerative Therapies for Central Nervous System Diseases: a Biomaterials Approach

(2013) Roger Y Tam et al.   NEUROPSYCHOPHARMACOLOGY

Design of three-dimensional engineered protein hydrogels for tailored control of neurite growth

(2012) Kyle J. Lampe et al.   Acta Biomaterialia

Hydrogel delivery of erythropoietin to the brain for endogenous stem cell stimulation after stroke injury

(2012) Yuanfei Wang et al.   BIOMATERIALS

TATVHL peptide-grafted alginate/poly(γ-glutamic acid) scaffolds with inverted colloidal crystal topology for neuronal differentiation of iPS cells

(2012) Yung-Chih Kuo et al.   BIOMATERIALS

BDNF blended chitosan scaffolds for human umbilical cord MSC transplants in traumatic brain injury therapy

(2012) Wei Shi et al.   BIOMATERIALS

Injectable hydrogels for central nervous system therapy

(2012) Malgosia M Pakulska et al.   Biomedical Materials

Characterization of hyaluronan-methylcellulose hydrogels for cell delivery to the injured spinal cord

(2012) Matthew J. Caicco et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

In vitro and in vivo toxicity of rinsed and aged nanocellulose-polypyrrole composites

(2012) Natalia Ferraz et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Stem Cell Therapy for Cerebral Ischemia: From Basic Science to Clinical Applications

(2012) Koji Abe et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Conductive Hydrogels: Mechanically Robust Hybrids for Use as Biomaterials

(2012) Rylie A. Green et al.   MACROMOLECULAR BIOSCIENCE

In vivo studies on angiogenic activity of two designer self-assembling peptide scaffold hydrogels in the chicken embryo chorioallantoic membrane

(2012) Xi Liu et al.   Nanoscale

Biocompatibility of polyaniline

(2012) Petr Humpolicek et al.   SYNTHETIC METALS

Engineering triiodothyronine (T3) nanoparticle for use in ischemic brain stroke

(2012) Alexander Mdzinarishvili et al.   Drug Delivery and Translational Research

Development and optimization of a dual-photoinitiator, emulsion-based technique for rapid generation of cell-laden hydrogel microspheres

(2011) C.L. Franco et al.   Acta Biomaterialia

Photoresponsive hydrogels for biomedical applications

(2011) Itsuro Tomatsu et al.   ADVANCED DRUG DELIVERY REVIEWS

Ten Years of Clinical Results With a Tissue-Engineered Pulmonary Valve

(2011) Pascal M. Dohmen et al.   ANNALS OF THORACIC SURGERY

Controlled epi-cortical delivery of epidermal growth factor for the stimulation of endogenous neural stem cell proliferation in stroke-injured brain

(2011) Michael J. Cooke et al.   BIOMATERIALS

Novel mechanically competent polysaccharide scaffolds for bone tissue engineering

(2011) S G Kumbar et al.   Biomedical Materials

Biocompatible alginate/nano bioactive glass ceramic composite scaffolds for periodontal tissue regeneration

(2011) Sowmya Srinivasan et al.   CARBOHYDRATE POLYMERS

Design properties of hydrogel tissue-engineering scaffolds

(2011) Junmin Zhu et al.   Expert Review of Medical Devices

Thermoresponsive poly(N-isopropylacrylamide)-g-methylcellulose hydrogel as a three-dimensional extracellular matrix for cartilage-engineered applications

(2011) Helena Sá-Lima et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Facile micropatterning of dual hydrogel systems for 3D models of neurite outgrowth

(2011) J. Lowry Curley et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

A pH-sensitive molecularly imprinted nanospheres/hydrogel composite as a coating for implantable biosensors

(2010) Chunyan Wang et al.   BIOMATERIALS

The effects of hyaluronic acid hydrogels with tunable mechanical properties on neural progenitor cell differentiation

(2010) Stephanie K. Seidlits et al.   BIOMATERIALS

Hydrogel cell patterning incorporating photocaged RGDS peptides

(2010) Catherine A. Goubko et al.   BIOMEDICAL MICRODEVICES

Tissue engineering for clinical applications

(2010) Sujata K. Bhatia   Biotechnology Journal

Injectable VEGF Hydrogels Produce Near Complete Neurological and Anatomical Protection following Cerebral Ischemia in Rats

(2010) Dwaine F. Emerich et al.   CELL TRANSPLANTATION

Vascular Protection and Restorative Therapy in Ischemic Stroke

(2010) Toru Yamashita et al.   CELL TRANSPLANTATION

Micropatterning as a tool to decipher cell morphogenesis and functions

(2010) M. Thery   JOURNAL OF CELL SCIENCE

A Brief Review of Stimulus-active Polymers Responsive to Thermal, Light, Magnetic, Electric, and Water/Solvent Stimuli

(2010) Harper Meng et al.   JOURNAL OF INTELLIGENT MATERIAL SYSTEMS AND STRUCTURES

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

A Small Synthetic Cripto Blocking Peptide Improves Neural Induction, Dopaminergic Differentiation, and Functional Integration of Mouse Embryonic Stem Cells in a Rat Model of Parkinson's Disease

(2010) Enza Lonardo et al.   STEM CELLS

Functional Improvement of Focal Cerebral Ischemia Injury by Subdural Transplantation of Induced Pluripotent Stem Cells with Fibrin Glue

(2010) Shih-Jen Chen et al.   STEM CELLS AND DEVELOPMENT

Controlling the Porosity and Microarchitecture of Hydrogels for Tissue Engineering

(2010) Nasim Annabi et al.   TISSUE ENGINEERING PART B-REVIEWS

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

Hyaluronic acid hydrogel loaded with genetically-engineered brain-derived neurotrophic factor as a neural cell carrier

(2009) Tadashi Nakaji-Hirabayashi et al.   BIOMATERIALS

The effect of substrate stiffness on adult neural stem cell behavior

(2009) Nic D. Leipzig et al.   BIOMATERIALS

Functional PEG–peptide hydrogels to modulate local inflammation inducedby the pro-inflammatory cytokine TNFα

(2009) Chien-Chi Lin et al.   BIOMATERIALS

Hydrogels as extracellular matrix mimics for 3D cell culture

(2009) Mark W. Tibbitt et al.   BIOTECHNOLOGY AND BIOENGINEERING

Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease

(2009) Krishanu Saha et al.   Cell Stem Cell

The complexity of neurobiological processes in acute ischemic stroke

(2009) R. Brouns et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Transplantation of Human Neural Precursor Cells in Matrigel Scaffolding Improves Outcome from Focal Cerebral Ischemia after Delayed Postischemic Treatment in Rats

(2009) Kunlin Jin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Light-sensitive Intelligent Drug Delivery Systems

(2009) Carmen Alvarez-Lorenzo et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Two-component protein-engineered physical hydrogels for cell encapsulation

(2009) Cheryl T. S. Wong Po Foo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial Cells Support Survival, Proliferation, and Neuronal Differentiation of Transplanted Adult Ischemia-Induced Neural Stem/Progenitor Cells After Cerebral Infarction

(2009) Nami Nakagomi et al.   STEM CELLS

Electrical Stimulation of Nerve Cells Using Conductive Nanofibrous Scaffolds for Nerve Tissue Engineering

(2009) Laleh Ghasemi-Mobarakeh et al.   TISSUE ENGINEERING PART A

In vitro analysis of PNIPAAm–PEG, a novel, injectable scaffold for spinal cord repair

(2008) Noelle Comolli et al.   Acta Biomaterialia

The effect of modified polysialic acid based hydrogels on the adhesion and viability of primary neurons and glial cells

(2008) Yohannes Haile et al.   BIOMATERIALS

Microporous nanofibrous fibrin-based scaffolds for bone tissue engineering

(2008) Thanaphum Osathanon et al.   BIOMATERIALS

Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration

(2008) Soo-Hong Lee et al.   BIOMATERIALS

Conducting polymers for neural interfaces: Challenges in developing an effective long-term implant

(2008) Rylie A. Green et al.   BIOMATERIALS

Length-scale mediated adhesion and directed growth of neural cells by surface-patterned poly(ethylene glycol) hydrogels

(2008) Peter Krsko et al.   BIOMATERIALS

Substrate Modulus Directs Neural Stem Cell Behavior

(2008) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

Extracellular matrix of the central nervous system: from neglect to challenge

(2008) Dieter R. Zimmermann et al.   HISTOCHEMISTRY AND CELL BIOLOGY

In situ gelling hydrogels for pharmaceutical and biomedical applications

(2008) Sophie R. Van Tomme et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Clinical transplantation of a tissue-engineered airway

(2008) Paolo Macchiarini et al.   LANCET

Stroke

(2008) Geoffrey A Donnan et al.   LANCET

Designer functionalized self-assembling peptide nanofiber scaffolds for growth, migration, and tubulogenesis of human umbilical vein endothelial cells

(2008) Xiumei Wang et al.   Soft Matter

Clinical Trials of Stroke Therapy: Which Cells, Which Patients?

(2008) L. R. Wechsler   STROKE

Cell Encapsulation in Biodegradable Hydrogels for Tissue Engineering Applications

(2008) Garret D. Nicodemus et al.   TISSUE ENGINEERING PART B-REVIEWS

Hydrogel mediated delivery of trophic factors for neural repair

(2008) Joshua S. Katz et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Thermoresponsive hydrogels in biomedical applications

(2007) Leda Klouda et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS