Review
Biotechnology & Applied Microbiology
Gretel S. Major, Jeremy W. Simcock, Tim B. F. Wood, Khoon S. Lim
Summary: Autologous fat grafting shows promise in repairing soft tissue deformities, but engineered solutions are needed to improve adipose tissue survival due to high resorption rates. Advances in material development and biofabrication have laid the foundation for functional adipose tissue constructs, but a balance is required between clinically feasible delivery and enhanced graft structural integrity. A new approach that combines clinical and research objectives can assist in developing mature adipose tissue constructs with controlled spatial arrangement and increased potential for neovascularization.
TRENDS IN BIOTECHNOLOGY
(2022)
Article
Polymer Science
Kristin Oskarsdotter, Catherine T. Nordgard, Peter Apelgren, Karin Saljo, Anita A. Solbu, Edwin Eliasson, Sanna Samfors, Henriette E. M. Saetrang, Lise Cathrine Asdahl, Eric M. Thompson, Christofer Troedsson, Stina Simonsson, Berit L. Strand, Paul Gatenholm, Lars Kolby
Summary: This study aimed to compare the effects of different crosslinking methods on autologous fat grafting. It was found that ex situ crosslinking using 3D bioprinting was more effective in maintaining the shape stability of the grafts, while in situ crosslinking, although improving fat cell distribution and survival, had poorer shape retention.
Article
Surgery
Catherine S. Chang, Michael A. Lanni, Michael N. Mirzabeigi, Louis P. Bucky
Summary: This study investigated the incidence of fat necrosis after large-volume fat grafting and identified risk factors associated with fat necrosis. The study found that factors such as larger graft volumes, higher body mass index, concurrent implant exchange with fat grafting, and fat grafting after lumpectomy or mastectomy without preexpansion were associated with increased rates of fat necrosis. Additionally, radiation therapy may be linked to a higher rate of complications.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Surgery
Qiuni Gao, Chengsheng Liu, Zuoliang Qi, Peiming Zhai, Jun Qi, Zhenyu Yang, Yuling Hu, Xihang Yuan
Summary: The study indicated that augmentation mammoplasty with EVE-assisted fat grafting is effective and satisfying in China. Utilizing Crisalix for 3D imaging acquisition proves to be a convenient and effective method for measuring breast volume.
AESTHETIC SURGERY JOURNAL
(2022)
Article
Dermatology
Evi M. Morandi, Selina Winkelmann, Lucie Dostal, Isabel Radacki, Ulrich M. Rieger, Benedikt Bauer, Ralph Verstappen, Dolores Wolfram, Thomas Bauer
Summary: Fat grafting is a well-established method in plastic surgery, and this retrospective study aimed to analyze the use of prophylactic antibiotics in fat grafting and compare complication rates for different protocols. The study found that prolonged use of prophylactic antibiotics did not lower the complication rate in fat grafting procedures. Risk factors for elevated complication rates included smoking, chemotherapy, and irradiation therapy.
INTERNATIONAL WOUND JOURNAL
(2022)
Article
Otorhinolaryngology
Kaitlynne Y. Pak, Spencer R. Anderson, Tyler L. Langenfeld, Kenneth Tan, Allison Slijepcevic, Sunishka Wimalawansa, Yadranko Ducic, Mark K. Wax, Sameep P. Kadakia
Summary: The arteriovenous loop is a viable option for vessel-depleted free tissue reconstruction, and previous radiation and surgery do not significantly affect the success rates of reconstruction.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2023)
Article
Surgery
Maurice Y. Nahabedian
Summary: Autologous fat grafting is widely accepted and routinely performed in breast augmentation and reconstruction, with small-volume grafting being more predictable than large-volume grafting. This article aims to review outcomes of large-volume and megavolume fat grafting in breast augmentation and reconstruction.
AESTHETIC SURGERY JOURNAL
(2021)
Article
Dermatology
Rajiv Raktoe, Anastasia K. A. L. Kwee, Marion Rietveld, Nick Marsidi, Roel Genders, Koen Quint, Remco van Doorn, Paul van Zuijlen, Abdoelwaheb E. L. Ghalbzouri
Summary: Deep burn injuries often result in severe scarring, such as hypertrophic scar formation. Autologous fat grafting, also known as lipofilling, has shown promise in reducing scar formation. This study aims to investigate the effects of fat grafting in 3D organotypic skin cultures resembling a hypertrophic scar-like environment.
EXPERIMENTAL DERMATOLOGY
(2023)
Article
Oncology
Marco Klinger, Agnese Losurdo, Andrea V. E. Lisa, Emanuela Morenghi, Valeriano Vinci, Fabio Corsi, Sara Albasini, Maria Cristina Leonardi, Barbara A. Jereczek-Fossa, Paolo Veronesi, Mario Rietjens, Luca Fabiocchi, Sonia Santicchia, Francesco Klinger, Andrea Loreti, Lucio Fortunato, Maria A. Bocchiotti, Fulvio A. Nicolo, Paolo Stringhini, Pier Camillo Parodi, Emanuele Rampino, Valentina Guarneri, Giulia Pagura, Erica Dalla Venezia, Graziano Meneghini, Tanja Kraljic, Paolo Persichetti, Mauro Barone, Nicola Vaia, Irene Zerini, Luca Grimaldi, Michele Riccio, Angelica Aquinati, Franco Bassetto, Vincenzo Vindigni, Luigi Ciuffreda, Corrado Tinterri, Armando Santoro
Summary: This study retrospectively analyzed early breast cancer patients and found that autologous fat grafting (AFG) did not significantly affect locoregional recurrence rate and locoregional recurrence-free survival rate compared to patients who did not undergo the procedure. The results suggest that AFG has no negative impact on cancer prognosis in early breast cancer patients.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Article
Surgery
Hui-Yi Hsiao, Chao-Yi Lai, Jia-Wei Liu, Yuan-Yuan Yu, Frank Chun-Shin Chang, Jung-Ju Huang
Summary: The study found that VASER liposuction method resulted in more angiogenesis and less fibrosis in the grafted fat tissue compared to traditional suction-assisted liposuction (TSAL). Furthermore, VASER-derived ASCs showed better quality in terms of cell differentiation capacity.
AESTHETIC SURGERY JOURNAL
(2021)
Article
Surgery
Alisa O. Girard, Christopher D. Lopez, Christina M. Ambrosino, Kristen P. Broderick
Summary: This study investigated the strategy of fat grafting in breast reconstruction and found that performing a single round of larger volume fat transfer at the time of implant placement can reduce the number of operative procedures without increased risks.
ANNALS OF PLASTIC SURGERY
(2023)
Review
Surgery
Teri N. Moak, Trina G. Ebersole, Damini Tandon, Marissa Tenenbaum
Summary: Autologous fat grafting, after undergoing multiple modifications, has become the standard of care for reconstruction and cosmetic enhancement of the breast and face. Increasing evidence suggests positive outcomes for patient and surgeon satisfaction, as well as overall aesthetic appearance.
AESTHETIC SURGERY JOURNAL
(2021)
Article
Surgery
Summer E. Hanson
Summary: Autologous fat grafting has a long history dating back to the late 19th century, with significant advancements in knowledge and techniques since then. Future directions in fat grafting may focus on optimizing current methods, expanding clinical indications, and selectively utilizing adipose graft components for various regenerative purposes.
AESTHETIC SURGERY JOURNAL
(2021)
Article
Engineering, Biomedical
Ruopiao Ni, Chao Luo, Hai Ci, Di Sun, Ran An, Zhenxing Wang, Jie Yang, Yiqing Li, Jiaming Sun
Summary: This study presents a hydrogel-based micro-tissue engineering technique to construct vascularized tissue-engineered breast grafts. By assembling adipose micro-tissues and vessel micro-tissues, a 3D printed breast-like scaffolds were implanted, resulting in significant adipose tissue regeneration and neo-vessel formation. The research expands the application of micro-tissue engineering and holds promise for creating heterogeneous tissue constructs in the future.
MATERIALS TODAY BIO
(2023)
Article
Surgery
Joseph M. Firriolo, Alexandra Conde-Green, Lee L. Q. Pu
Summary: Autologous fat grafting is regarded as an ideal filler with the ability to restore soft-tissue contour. Recent research has shown its regenerative capacity, primarily due to the presence of stem cells and preadipocytes in adipose tissue, opening up new possibilities for regenerative surgery.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Editorial Material
Surgery
Roger K. Khouri
PLASTIC AND RECONSTRUCTIVE SURGERY
(2018)
Editorial Material
Surgery
Roger K. Khouri
PLASTIC AND RECONSTRUCTIVE SURGERY
(2019)
Editorial Material
Surgery
Roger K. Khouri
PLASTIC AND RECONSTRUCTIVE SURGERY
(2018)
Editorial Material
Surgery
Roger K. Khouri, Raoul-Emil R. Khouri, Khalil R. Khouri, Gerard Ateshian
PLASTIC AND RECONSTRUCTIVE SURGERY
(2018)
Editorial Material
Surgery
Kimberly S. Khouri, Roger K. Khouri, Roger K. Khouri
Article
Dermatology
Julien Succar, Giorgio Giatsidis, Nanze Yu, Kazi Hassan, Roger Khouri, Michael F. Gurish, Gunnar Pejler, Magnus Abrink, Dennis Paul Orgill
ADVANCES IN WOUND CARE
(2019)
Article
Urology & Nephrology
Daniel Wong, Vishnuvardhan Ganesan, Inkkaruch Kuprasertkul, Roger K. Khouri, Gary E. Lemack
Editorial Material
Surgery
Kimberly S. Khouri, Roger K. Khouri
PLASTIC AND RECONSTRUCTIVE SURGERY
(2019)
Article
Urology & Nephrology
Roger K. Khouri, Adam S. Baumgarten, Nicolas M. Ortiz, Ellen E. Ward, Ryan C. Baker, Maia E. VanDyke, Yooni A. Yi, Steven J. Hudak, Allen F. Morey
Article
Urology & Nephrology
Adam S. Baumgarten, Mehraban Kavoussi, Maia E. VanDyke, Nicolas M. Ortiz, Roger K. Khouri, Ellen E. Ward, Steven J. Hudak, Allen F. Morey
Article
Urology & Nephrology
Roger K. Khouri, Nicolas M. Ortiz, Adam S. Baumgarten, Ellen E. Ward, Maia E. VanDyke, Steven J. Hudak, Allen F. Morey
Article
Urology & Nephrology
Alexander P. Kenigsberg, Roger K. Khouri, Amy Kuprasertkul, Daniel Wong, Vishnu Ganesan, Gary E. Lemack
Editorial Material
Urology & Nephrology
Adam S. Baumgarten, Mehraban Kavoussi, Nicolas M. Ortiz, Roger K. Khouri, Ellen E. Ward, Steven J. Hudak, Allen F. Morey
Editorial Material
Surgery
Roger K. Khouri
PLASTIC AND RECONSTRUCTIVE SURGERY
(2020)
Article
Urology & Nephrology
Roger K. Khouri, Byron D. Joyner, Gary E. Lemack