Pros and Cons of Antigen-Presenting Cell Targeted Tumor Vaccines

Targeting myeloid cells using nanoparticles to improve cancer immunotherapy

(2015) Zohreh Amoozgar et al.   ADVANCED DRUG DELIVERY REVIEWS

CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses

(2015) Rodney A. Rosalia et al.   BIOMATERIALS

Myeloid regulatory cells in tumor spreading and metastasis

(2015) Anton A. Keskinov et al.   IMMUNOBIOLOGY

In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model

(2015) Joana M. Silva et al.   JOURNAL OF CONTROLLED RELEASE

Tumor-Infiltrating Dendritic Cells in Cancer Pathogenesis

(2015) Jo Marie Tran Janco et al.   JOURNAL OF IMMUNOLOGY

Criteria for Dendritic Cell Receptor Selection for Efficient Antibody-Targeted Vaccination

(2015) Anika Reuter et al.   JOURNAL OF IMMUNOLOGY

Virological and Preclinical Characterization of a Dendritic Cell Targeting, Integration-deficient Lentiviral Vector for Cancer Immunotherapy

(2015) Jared M. Odegard et al.   JOURNAL OF IMMUNOTHERAPY

Dissolving Microneedle Delivery of Nanoparticle-Encapsulated Antigen Elicits Efficient Cross-Priming and Th1 Immune Responses by Murine Langerhans Cells

(2015) Marija Zaric et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Targeting the tumor microenvironment to enhance antitumor immune responses

(2015) Kevin Van der Jeught et al.   Oncotarget

Immunogenicity of targeted lentivectors

(2015) Cleo Goyvaerts et al.   Oncotarget

Nanogel-Based Immunologically Stealth Vaccine Targets Macrophages in the Medulla of Lymph Node and Induces Potent Antitumor Immunity

(2014) Daisuke Muraoka et al.   ACS Nano

Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

(2014) Miranda L. Broz et al.   CANCER CELL

Toll-like receptor agonists shape the immune responses to a mannose receptor-targeted cancer vaccine

(2014) Li-Zhen He et al.   Cellular & Molecular Immunology

Aligning bona fide dendritic cell populations across species

(2014) Charles-Antoine Dutertre et al.   CELLULAR IMMUNOLOGY

Dendritic cells and cancer immunotherapy

(2014) Kristen J Radford et al.   CURRENT OPINION IN IMMUNOLOGY

Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas

(2014) Gianfranco Picco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The ReNAissanCe of mRNA-based cancer therapy

(2014) Sandra Van Lint et al.   Expert Review of Vaccines

Development and Function of Dendritic Cell Subsets

(2014) Alexander Mildner et al.   IMMUNITY

Targeting human dendritic cells in situ to improve vaccines

(2014) Kartik Sehgal et al.   IMMUNOLOGY LETTERS

Development of a dendritic cell-targeting lipopeptide as an immunoadjuvant that inhibits tumor growth without inducing local inflammation

(2014) Takashi Akazawa et al.   INTERNATIONAL JOURNAL OF CANCER

The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy

(2014) Heleen Dewitte et al.   JOURNAL OF CONTROLLED RELEASE

Lentiviral-Mediated Transcriptional Targeting of Dendritic Cells for Induction of T Cell Tolerance In Vivo

(2014) C. Dresch et al.   JOURNAL OF IMMUNOLOGY

Antigen Delivery to CD11c+CD8- Dendritic Cells Induces Protective Immune Responses against Experimental Melanoma in Mice In Vivo

(2014) K. Neubert et al.   JOURNAL OF IMMUNOLOGY

Targeted Delivery of α-Galactosylceramide to CD8α+Dendritic Cells Optimizes Type I NKT Cell–Based Antitumor Responses

(2014) Elodie Macho-Fernandez et al.   JOURNAL OF IMMUNOLOGY

Antigen Targeting to CD11b+Dendritic Cells in Association with TLR4/TRIF Signaling Promotes Strong CD8+T Cell Responses

(2014) Gilles Dadaglio et al.   JOURNAL OF IMMUNOLOGY

Induction of Potent CD8 T Cell Cytotoxicity by Specific Targeting of Antigen to Cross-Presenting Dendritic Cells In Vivo via Murine or Human XCR1

(2014) Evelyn Hartung et al.   JOURNAL OF IMMUNOLOGY

Nanoparticle-Mediated Combinatorial Targeting of Multiple Human Dendritic Cell (DC) Subsets Leads to Enhanced T Cell Activation via IL-15–Dependent DC Crosstalk

(2014) Kartik Sehgal et al.   JOURNAL OF IMMUNOLOGY

Aptamer-targeted Antigen Delivery

(2014) Brian C Wengerter et al.   MOLECULAR THERAPY

Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment

(2014) Heleen Dewitte et al.   Nano Today

Bovine Serum Albumin Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery via Dry Powder Inhalation

(2014) Nitesh K. Kunda et al.   PHARMACEUTICAL RESEARCH

Immunization of Mice with Lentiviral Vectors Targeted to MHC Class II+ Cells Is Due to Preferential Transduction of Dendritic Cells In Vivo

(2014) Séverine Ciré et al.   PLoS One

Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist

(2014) K. Kobiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Antigen-Specific Immunity with a Vaccine Targeting NY-ESO-1 to the Dendritic Cell Receptor DEC-205

(2014) M. V. Dhodapkar et al.   Science Translational Medicine

Lymphatic-targeted cationic liposomes: A robust vaccine adjuvant for promoting long-term immunological memory

(2014) Ce Wang et al.   VACCINE

Attenuated Listeria monocytogenes: a powerful and versatile vector for the future of tumor immunotherapy

(2014) Laurence M. Wood et al.   Frontiers in Cellular and Infection Microbiology

Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes

(2014) L. Jeanbart et al.   Cancer Immunology Research

Dendritic Cell-Targeted Vaccines

(2014) Lillian Cohn et al.   Frontiers in Immunology

Harnessing Human Cross-Presenting CLEC9A+XCR1+ Dendritic Cells for Immunotherapy

(2014) Kirsteen M. Tullett et al.   Frontiers in Immunology

Paradigm Shift in Dendritic Cell-Based Immunotherapy: From in vitro Generated Monocyte-Derived DCs to Naturally Circulating DC Subsets

(2014) Florian Wimmers et al.   Frontiers in Immunology

Skin Dendritic Cell Targeting via Microneedle Arrays Laden with Antigen-Encapsulated Poly-d,l-lactide-co-Glycolide Nanoparticles Induces Efficient Antitumor and Antiviral Immune Responses

(2013) Marija Zaric et al.   ACS Nano

Human dendritic cells subsets as targets and vectors for therapy

(2013) Eynav Klechevsky et al.   Annals of the New York Academy of Sciences

Nanobodies: Natural Single-Domain Antibodies

(2013) Serge Muyldermans   Annual Review of Biochemistry

Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response

(2013) Susan N. Thomas et al.   BIOMATERIALS

CD141+ dendritic cells produce prominent amounts of IFN-  after dsRNA recognition and can be targeted via DEC-205 in humanized mice

(2013) S. Meixlsperger et al.   BLOOD

Robust T-cell stimulation by Epstein-Barr virus-transformed B cells after antigen targeting to DEC-205

(2013) C. S. Leung et al.   BLOOD

Targeting dendritic cells--why bother?

(2013) M. Kreutz et al.   BLOOD

DNA vaccines targeting the encoded antigens to dendritic cells induce potent antitumor immunity in mice

(2013) Jun Cao et al.   BMC IMMUNOLOGY

Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients

(2013) J. Tel et al.   CANCER RESEARCH

Organization of the mouse and human DC network

(2013) Andreas Schlitzer et al.   CURRENT OPINION IN IMMUNOLOGY

Camelid single-domain antibody-fragment engineering for (pre)clinicalin vivomolecular imaging applications: adjusting the bullet to its target

(2013) Jens De Vos et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

A novel peptide carrier for efficient targeting of antigens and nucleic acids to dendritic cells

(2013) Mouldy Sioud et al.   FASEB JOURNAL

Biosafety Features of Lentiviral Vectors

(2013) Axel Schambach et al.   HUMAN GENE THERAPY

Controlling immune responses by targeting antigens to dendritic cell subsets and B cells

(2013) Craig P. Chappell et al.   INTERNATIONAL IMMUNOLOGY

A platform to screen for C-type lectin receptor-binding carbohydrates and their potential for cell-specific targeting and immune modulation

(2013) Maha Maglinao et al.   JOURNAL OF CONTROLLED RELEASE

Targeting Uptake Receptors on Human Plasmacytoid Dendritic Cells Triggers Antigen Cross-Presentation and Robust Type I IFN Secretion

(2013) J. Tel et al.   JOURNAL OF IMMUNOLOGY

Targeting of Human Antigen-Presenting Cell Subsets

(2013) C. Goyvaerts et al.   JOURNAL OF VIROLOGY

Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors

(2013) Scott N Furlan et al.   mAbs

Design of a Novel Integration-deficient Lentivector Technology That Incorporates Genetic and Posttranslational Elements to Target Human Dendritic Cells

(2013) Semih U Tareen et al.   MOLECULAR THERAPY

Visualization of DC-SIGN-Mediated Entry Pathway of Engineered Lentiviral Vectors in Target Cells

(2013) Yarong Liu et al.   PLoS One

Peripherally Administered Nanoparticles Target Monocytic Myeloid Cells, Secondary Lymphoid Organs and Tumors in Mice

(2013) Iraklis C. Kourtis et al.   PLoS One

The Specificity of Targeted Vaccines for APC Surface Molecules Influences the Immune Response Phenotype

(2013) Gunnveig Grødeland et al.   PLoS One

Dendritic Cell-Specific Delivery of Flt3L by Coronavirus Vectors Secures Induction of Therapeutic Antitumor Immunity

(2013) Christian Perez-Shibayama et al.   PLoS One

PostexitSurface Engineering of Retroviral/Lentiviral Vectors

(2013) Christoph Metzner et al.   Biomed Research International

Naturally circulating dendritic cells to vaccinate cancer patients

(2013) Kalijn F. Bol et al.   OncoImmunology

Targeting dendritic cells with antigen via dendritic cell-associated promoters

(2012) V Moulin et al.   CANCER GENE THERAPY

IL-15 augments antitumoral activity of an ErbB2/HER2 cancer vaccine targeted to professional antigen-presenting cells

(2012) Ute E. Burkhardt et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Nanobody-Based Targeting of the Macrophage Mannose Receptor for EffectiveIn VivoImaging of Tumor-Associated Macrophages

(2012) Kiavash Movahedi et al.   CANCER RESEARCH

Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy

(2012) S. Van Lint et al.   CANCER RESEARCH

Transcriptional targeting of DCs with lentiviral vectors induces antigen-specific tolerance in a mouse model of multiple sclerosis

(2012) B de Andrade Pereira et al.   GENE THERAPY

Development of the Nanobody display technology to target lentiviral vectors to antigen-presenting cells

(2012) C Goyvaerts et al.   GENE THERAPY

Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

(2012) Muzlifah Haniffa et al.   IMMUNITY

Antigen-loaded pH-sensitive hydrogel microparticles are taken up by dendritic cells with no requirement for targeting antibodies

(2012) Laura E. Ruff et al.   Integrative Biology

Targeting the antigen encoded by adenoviral vectors to the DEC205 receptor modulates the cellular and humoral immune response

(2012) Matthias Tenbusch et al.   INTERNATIONAL IMMUNOLOGY

Targeting tumor antigens to dendritic cells using particulate carriers

(2012) Medha D. Joshi et al.   JOURNAL OF CONTROLLED RELEASE

Nanogel vaccines targeting dendritic cells: Contributions of the surface decoration and vaccine cargo on cell targeting and activation

(2012) L.J. Thomann-Harwood et al.   JOURNAL OF CONTROLLED RELEASE

Resident CD141 (BDCA3)+dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

(2012) Chung-Ching Chu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10–producing suppressive CD4+T cells

(2012) Dapeng Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antibody-Antigen-Adjuvant Conjugates Enable Co-Delivery of Antigen and Adjuvant to Dendritic Cells in Cis but Only Have Partial Targeting Specificity

(2012) Martin Kreutz et al.   PLoS One

Dendritic Cell Based PSMA Immunotherapy for Prostate Cancer Using a CD40-Targeted Adenovirus Vector

(2012) Briana Jill Williams et al.   PLoS One

Dendritic Cell-Directed Vaccination with a Lentivector Encoding PSCA for Prostate Cancer in Mice

(2012) Liang Xiao et al.   PLoS One

Clinical Development of Listeria monocytogenes–Based Immunotherapies

(2012) Dung T. Le et al.   SEMINARS IN ONCOLOGY

Dendritic Cells for Active Anti-Cancer Immunotherapy: Targeting Activation Pathways Through Genetic Modification

(2012) Karine Breckpot et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Targeting Dendritic Cells in vivo for Cancer Therapy

(2012) Irina Caminschi et al.   Frontiers in Immunology

Expression of XCR1 Characterizes the Batf3-Dependent Lineage of Dendritic Cells Capable of Antigen Cross-Presentation

(2012) Annabell Bachem et al.   Frontiers in Immunology

Targeting dendritic cells in situ for breast cancer immunotherapy

(2012) Bei Wang   OncoImmunology

Targeted DNA vaccines for enhanced induction of idiotype-specific B and T cells

(2012) Agnete B. Fredriksen et al.   Frontiers in Oncology

Antitumor activity of liposomal ErbB2/HER2 epitope peptide-based vaccine constructs incorporating TLR agonists and mannose receptor targeting

(2011) Jean-Sébastien Thomann et al.   BIOMATERIALS

Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity

(2011) P. J. Tacken et al.   BLOOD

Adjuvant Combination and Antigen Targeting as a Strategy to Induce Polyfunctional and High-Avidity T-Cell Responses against Poorly Immunogenic Tumors

(2011) F. Aranda et al.   CANCER RESEARCH

Potent Antitumor Immunity Generated by a CD40-Targeted Adenoviral Vaccine

(2011) B. N. Hangalapura et al.   CANCER RESEARCH

Peptide-Conjugated PAMAM Dendrimer as a Universal DNA Vaccine Platform to Target Antigen-Presenting Cells

(2011) P. Daftarian et al.   CANCER RESEARCH

Phase I Study Utilizing a Novel Antigen-Presenting Cell-Targeted Vaccine with Toll-like Receptor Stimulation to Induce Immunity to Self-antigens in Cancer Patients

(2011) M. A. Morse et al.   CLINICAL CANCER RESEARCH

Immuno-imaging using nanobodies

(2011) Ilse Vaneycken et al.   CURRENT OPINION IN BIOTECHNOLOGY

Targeted idiotype-fusion DNA vaccines for human multiple myeloma: preclinical testing

(2011) Marianne Frøyland et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Vaccination with filamentous bacteriophages targeting DEC-205 induces DC maturation and potent anti-tumor T-cell responses in the absence of adjuvants

(2011) Rossella Sartorius et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of anti-tumor immunity and T-cell responses using nanodelivery systems engrafting TLR-5 ligand

(2011) Amulya K Panda   Expert Review of Vaccines

Lentiviral vectors for induction of self-differentiation and conditional ablation of dendritic cells

(2011) M Pincha et al.   GENE THERAPY

Lentiviral Vectors Targeted to MHC II Are Effective in Immunization

(2011) Alexander Ageichik et al.   HUMAN GENE THERAPY

Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin

(2011) Cristina Mansilla et al.   INTERNATIONAL JOURNAL OF CANCER

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets

(2011) Kathrin Kastenmüller et al.   JOURNAL OF CLINICAL INVESTIGATION

Treml4, an Ig Superfamily Member, Mediates Presentation of Several Antigens to T Cells In Vivo, Including Protective Immunity to HER2 Protein

(2011) H. Hemmi et al.   JOURNAL OF IMMUNOLOGY

ISCOMATRIX Adjuvant Combines Immune Activation with Antigen Delivery to Dendritic Cells In Vivo Leading to Effective Cross-Priming of CD8+ T Cells

(2011) P. Duewell et al.   JOURNAL OF IMMUNOLOGY

Antigen Delivery to Plasmacytoid Dendritic Cells via BST2 Induces Protective T Cell-Mediated Immunity

(2011) J. Loschko et al.   JOURNAL OF IMMUNOLOGY

HER2-based recombinant immunogen to target DCs through FcγRs for cancer immunotherapy

(2011) Ilaria Grazia Zizzari et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

DARPins: An Efficient Targeting Domain for Lentiviral Vectors

(2011) Robert C Münch et al.   MOLECULAR THERAPY

Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses

(2011) M Semmrich et al.   Mucosal Immunology

Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA

(2011) Federico Perche et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection

(2011) Linda M. Wakim et al.   NATURE

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

(2011) J. Idoyaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transduction of Human Cells with Polymer-complexed Ecotropic Lentivirus for Enhanced Biosafety

(2011) Bonnie Barrilleaux et al.   Jove-Journal of Visualized Experiments

C-type Lectin Receptors for Tumor Eradication: Future Directions

(2011) Ingeborg Streng-Ouwehand et al.   Cancers

Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas

(2010) Cheolho Cheong et al.   CELL

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A

(2010) Olivier P. Joffre et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lentiviral-Human Heme Oxygenase Targeting Endothelium Improved Vascular Function in Angiotensin II Animal Model of Hypertension

(2010) Jian Cao et al.   HUMAN GENE THERAPY

Continuous Expression of the Transcription Factor E2-2 Maintains the Cell Fate of Mature Plasmacytoid Dendritic Cells

(2010) Hiyaa S. Ghosh et al.   IMMUNITY

Designing Vaccines Based on Biology of Human Dendritic Cell Subsets

(2010) Karolina Palucka et al.   IMMUNITY

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

DC subsets in positive and negative regulation of immunity

(2010) Caroline Coquerelle et al.   IMMUNOLOGICAL REVIEWS

The CD8+dendritic cell subset

(2010) Ken Shortman et al.   IMMUNOLOGICAL REVIEWS

Ag-bearing liposomes engrafted with peptides that interact with CD11c/CD18 induce potent Ag-specific and antitumor immunity

(2010) Abdus Faham et al.   INTERNATIONAL JOURNAL OF CANCER

Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+cells as homologues of mouse CD8+dendritic cells

(2010) Annabell Bachem et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selective Transduction of Dendritic Cells in Human Lymph Nodes and Superior Induction of High-avidity Melanoma-reactive Cytotoxic T Cells by a CD40-targeted Adenovirus

(2010) Basav N. Hangalapura et al.   JOURNAL OF IMMUNOTHERAPY

Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells

(2010) Mingjie Li et al.   JOURNAL OF NEUROSCIENCE METHODS

Nanobodies as Tools for In Vivo Imaging of Specific Immune Cell Types

(2010) K. De Groeve et al.   JOURNAL OF NUCLEAR MEDICINE

Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

(2010) Stefan Stein et al.   NATURE MEDICINE

Immunogenicity of a recombinant lentiviral vector carrying human telomerase tumor antigen in HLA-B*0702 transgenic mice

(2010) Sylvie Rusakiewicz et al.   VACCINE

Vaccines delivered by integration-deficient lentiviral vectors targeting dendritic cells induces strong antigen-specific immunity

(2010) Biliang Hu et al.   VACCINE

Dendritic Cell-Specific Antigen Delivery by Coronavirus Vaccine Vectors Induces Long-Lasting Protective Antiviral and Antitumor Immunity

(2010) L. Cervantes-Barragan et al.   mBio

Toll-like Receptor and RIG-1-like Receptor Signaling

(2009) Taro Kawai et al.   Annals of the New York Academy of Sciences

The Human Cancer Antigen Mesothelin Is More Efficiently Presented to the Mouse Immune System when Targeted to the DEC-205/CD205 Receptor on Dendritic Cells

(2009) Bei Wang et al.   Annals of the New York Academy of Sciences

A Novel Human Her-2/neu Chimeric Molecule Expressed by Listeria monocytogenes Can Elicit Potent HLA-A2 Restricted CD8-positive T cell Responses and Impact the Growth and Spread of Her-2/neu-positive Breast Tumors

(2009) M. M. Seavey et al.   CLINICAL CANCER RESEARCH

Improving vaccines by targeting antigens to dendritic cells

(2009) Ken Shortman et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Nonintegrating Lentiviral Vectors Can Effectively Deliver Ovalbumin Antigen for Induction of Antitumor Immunity

(2009) Biliang Hu et al.   HUMAN GENE THERAPY

Single-Chain Antibodies That Target Lentiviral Vectors to MHC Class II on Antigen-Presenting Cells

(2009) Francesca Gennari et al.   HUMAN GENE THERAPY

Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network

(2009) Laurent Chorro et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cytokine stimulation and the choice of promoter are critical factors for the efficient transduction of mouse T cells with HIV-1 vectors

(2009) David E. Gilham et al.   JOURNAL OF GENE MEDICINE

HIV-1 Gag-specific immunity induced by a lentivector-based vaccine directed to dendritic cells

(2009) B. Dai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Engineering of Viral Gene Delivery Vehicles

(2008) David V. Schaffer et al.   Annual Review of Biomedical Engineering

Retroviral Display and High Throughput Screening

(2008) Christian Buchholz et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Delivery of antigen using a novel mannosylated dendrimer potentiates immunogenicityin vitro andin vivo

(2008) Kuo-Ching Sheng et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

(2008) David Sancho et al.   JOURNAL OF CLINICAL INVESTIGATION

Dendritic Cells: A Critical Player in Cancer Therapy?

(2008) Anna Karolina Palucka et al.   JOURNAL OF IMMUNOTHERAPY

Correction of Laminin-5 Deficiency in Human Epidermal Stem Cells by Transcriptionally Targeted Lentiviral Vectors

(2008) Francesca Di Nunzio et al.   MOLECULAR THERAPY

Engineered lentivector targeting of dendritic cells for in vivo immunization

(2008) Lili Yang et al.   NATURE BIOTECHNOLOGY