Na+ entry through heteromeric TRPC4/C1 channels mediates (−)Englerin A-induced cytotoxicity in synovial sarcoma cells
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Na+ entry through heteromeric TRPC4/C1 channels mediates (−)Englerin A-induced cytotoxicity in synovial sarcoma cells
Authors
Keywords
-
Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-11-29
DOI
10.1038/s41598-017-17303-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Functional Characterization of Transient Receptor Potential (TRP) Channel C5 in Female Murine Gonadotropes
- (2017) Andreas Beck et al. ENDOCRINOLOGY
- Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels
- (2017) Hussein N. Rubaiy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Englerins: A Comprehensive Review
- (2017) Zhenhua Wu et al. JOURNAL OF NATURAL PRODUCTS
- Englerin A induces an acute inflammatory response and reveals lipid metabolism and ER stress as targetable vulnerabilities in renal cell carcinoma
- (2017) Ayse Batova et al. PLoS One
- Unveiling (−)-Englerin A as a Modulator of L-Type Calcium Channels
- (2016) Tiago Rodrigues et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The interaction domains of transient receptor potential canonical (TRPC)1/4 and TRPC1/5 heteromultimeric channels
- (2016) Jongyun Myeong et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Englerin A Inhibits EWS-FLI1 DNA Binding in Ewing Sarcoma Cells
- (2016) Vittorio Caropreso et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- (−)-Englerin A-evoked Cytotoxicity Is Mediated by Na+Influx and Counteracted by Na+/K+-ATPase
- (2016) Melanie J. Ludlow et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- (−)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels
- (2015) Yasemin Akbulut et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A background Ca2+entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling
- (2015) Juan E. Camacho Londoño et al. EUROPEAN HEART JOURNAL
- Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent
- (2015) Carole Sourbier et al. Oncotarget
- Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation
- (2015) Cheryl Carson et al. PLoS One
- The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor
- (2014) Hiroka Suzuki et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Identification of a Membrane-targeting Domain of the Transient Receptor Potential Canonical (TRPC)4 Channel Unrelated to Its Formation of a Tetrameric Structure
- (2014) Jongyun Myeong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A rat knockout model implicates TRPC4 in visceral pain sensation
- (2014) K.N. Westlund et al. NEUROSCIENCE
- Englerin A Stimulates PKCθ to Inhibit Insulin Signaling and to Simultaneously Activate HSF1: Pharmacologically Induced Synthetic Lethality
- (2013) Carole Sourbier et al. CANCER CELL
- Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy
- (2013) Richard T Williams et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Gramicidin A Induces Metabolic Dysfunction and Energy Depletion Leading to Cell Death in Renal Cell Carcinoma Cells
- (2013) Justin M. David et al. MOLECULAR CANCER THERAPEUTICS
- Englerin A Selectively Induces Necrosis in Human Renal Cancer Cells
- (2012) Florian J. Sulzmaier et al. PLoS One
- Transient Receptor Potential Channel 1 (TRPC1) Reduces Calcium Permeability in Heteromeric Channel Complexes
- (2011) Ursula Storch et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of ML204, a Novel Potent Antagonist That Selectively Modulates Native TRPC4/C5 Ion Channels
- (2011) Melissa Miller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An environmental sensor, TRPV4 is a novel regulator of intracellular Ca2+ in human synoviocytes
- (2009) Yuka Itoh et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Essential Role for TRPC5 in Amygdala Function and Fear-Related Behavior
- (2009) Antonio Riccio et al. CELL
- Deletion of TRPC4 and TRPC6 in Mice Impairs Smooth Muscle Contraction and Intestinal Motility In Vivo
- (2009) Volodymyr V. Tsvilovskyy et al. GASTROENTEROLOGY
- Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
- (2009) Aimee L. Jackson et al. NATURE REVIEWS DRUG DISCOVERY
- Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, fromPhyllanthus engleri
- (2008) Ranjala Ratnayake et al. ORGANIC LETTERS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now