Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

Natural products: A continuing source of novel drug leads

(2013) Gordon M. Cragg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Englerin A Stimulates PKCθ to Inhibit Insulin Signaling and to Simultaneously Activate HSF1: Pharmacologically Induced Synthetic Lethality

(2013) Carole Sourbier et al.   CANCER CELL

Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway

(2013) Dong-Mei Zhang et al.   CARCINOGENESIS

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Formal Synthesis of (−)-Englerin A and Cytotoxicity Studies of Truncated Englerins

(2012) Jing Xu et al.   Chemistry-An Asian Journal

Renal cancer: Oxygen meets metabolism

(2012) Volker H. Haase   EXPERIMENTAL CELL RESEARCH

Englerin A Selectively Induces Necrosis in Human Renal Cancer Cells

(2012) Florian J. Sulzmaier et al.   PLoS One

Regulation and Function of Autophagy during Cell Survival and Cell Death

(2012) G. Das et al.   Cold Spring Harbor Perspectives in Biology

Metabolic Stress in Autophagy and Cell Death Pathways

(2012) B. J. Altman et al.   Cold Spring Harbor Perspectives in Biology

Novel agents in renal carcinoma: a reality check

(2012) Yana G. Najjar et al.   Therapeutic Advances in Medical Oncology

Carminomycin I Is an Apoptosis Inducer That Targets the Golgi Complex in Clear Cell Renal Carcinoma Cells

(2011) G. M. Woldemichael et al.   CANCER RESEARCH

Chemical Synthesis of the Englerins

(2011) Rebecca H. Pouwer et al.   Chemistry-An Asian Journal

Update on targeted therapies for clear cell renal cell carcinoma

(2011) Eric A Singer et al.   CURRENT OPINION IN ONCOLOGY

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Inhibition of active autophagy induces apoptosis and increases chemosensitivity in cholangiocarcinoma

(2011) Yu-Jie Hou et al.   LABORATORY INVESTIGATION

4E-BP1 Is a Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways that Integrates Their Function in Tumors

(2010) Qing-Bai She et al.   CANCER CELL

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VHL and HIF signalling in renal cell carcinogenesis

(2010) Marcella M Baldewijns et al.   JOURNAL OF PATHOLOGY

Towards artificial terpene cyclases

(2010) Matthieu Willot et al.   Nature Chemistry

The role of VHL in clear-cell renal cell carcinoma and its relation to targeted therapy

(2009) Peter E. Clark   KIDNEY INTERNATIONAL

Rapamycin protects against rotenone-induced apoptosis through autophagy induction

(2009) T. Pan et al.   NEUROSCIENCE

A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy

(2008) Sandra Turcotte et al.   CANCER CELL

Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors

(2008) M. L. Nickerson et al.   CLINICAL CANCER RESEARCH

Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, fromPhyllanthus engleri

(2008) Ranjala Ratnayake et al.   ORGANIC LETTERS