Quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis

Yeast membrane proteomics using leucine metabolic labelling: Bioinformatic data processing and exemplary application to the ER-intramembrane protease Ypf1

(2016) Lars Nilse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Sprouting angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid-like 2 protein (RHBDL2)

(2016) Peter J. Noy et al.   FASEB JOURNAL

Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα

(2016) Lina Wunderle et al.   Scientific Reports

Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway

(2015) Wei Song et al.   Nature Communications

Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures

(2014) S. Zoll et al.   EMBO JOURNAL

RHBDL2 Is a Critical Membrane Protease for Anoikis Resistance in Human Malignant Epithelial Cells

(2014) Tsung-Lin Cheng et al.   TheScientificWorldJOURNAL

The role of proteases in regulating Eph/ephrin signaling

(2014) Lakmali Atapattu et al.   Cell Adhesion & Migration

New directions in ER stress-induced cell death

(2013) Susan E. Logue et al.   APOPTOSIS

Collagen recognition and transmembrane signalling by discoidin domain receptors

(2012) Federico Carafoli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

“Sprouting angiogenesis”, a reappraisal

(2012) Domenico Ribatti et al.   DEVELOPMENTAL BIOLOGY

Ubiquitin-Dependent Intramembrane Rhomboid Protease Promotes ERAD of Membrane Proteins

(2012) Lina Fleig et al.   MOLECULAR CELL

The Proteomics Identifications (PRIDE) database and associated tools: status in 2013

(2012) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Transmembrane Collagen Receptors

(2011) Birgit Leitinger   Annual Review of Cell and Developmental Biology

Cell surface adhesion molecules and adhesion-initiated signaling: Understanding of anoikis resistance mechanisms and therapeutic opportunities

(2011) Xiaoling Zhong et al.   CELLULAR SIGNALLING

Mammalian EGF receptor activation by the rhomboid protease RHBDL2

(2011) Colin Adrain et al.   EMBO REPORTS

Persistent elevation of hepatocyte growth factor activator inhibitors in cholangiopathies affects liver fibrosis and differentiation

(2011) Hsiang-Po Huang et al.   HEPATOLOGY

Functions of Rhomboid Family Protease RHBDL2 and Thrombomodulin in Wound Healing

(2011) Tsung-Lin Cheng et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular and Cellular Mechanisms of Ectodomain Shedding

(2010) Kazutaka Hayashida et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Reducing agents induce thrombomodulin shedding in human endothelial cells

(2010) Mario Menschikowski et al.   THROMBOSIS RESEARCH

Imbalance in the Pro–Hepatocyte Growth Factor Activation System in Bleomycin-Induced Lung Fibrosis in Mice

(2009) Sophie Phin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sequence-Specific Intramembrane Proteolysis: Identification of a Recognition Motif in Rhomboid Substrates

(2009) Kvido Strisovsky et al.   MOLECULAR CELL

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Sequential Expression of Pluripotency Markers during Direct Reprogramming of Mouse Somatic Cells

(2008) Tobias Brambrink et al.   Cell Stem Cell