A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFNγ
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFNγ
Authors
Keywords
-
Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-08-21
DOI
10.1038/s41598-017-09639-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization
- (2017) Eleni Vergadi et al. JOURNAL OF IMMUNOLOGY
- Substance P Promotes Wound Healing in Diabetes by Modulating Inflammation and Macrophage Phenotype
- (2015) Ermelindo C. Leal et al. AMERICAN JOURNAL OF PATHOLOGY
- Monocyte and Macrophage Plasticity in Tissue Repair and Regeneration
- (2015) Amitava Das et al. AMERICAN JOURNAL OF PATHOLOGY
- Macrophage activation and its role in repair and pathology after spinal cord injury
- (2015) John C. Gensel et al. BRAIN RESEARCH
- Monocyte trafficking across the vessel wall
- (2015) Teresa Gerhardt et al. CARDIOVASCULAR RESEARCH
- Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms
- (2015) Tamás Rőszer MEDIATORS OF INFLAMMATION
- Biological and Pharmacological Aspects of the NK1-Receptor
- (2015) Susana Garcia-Recio et al. Biomed Research International
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- HIV infection of macrophages is enhanced in the presence of increased expression of CD163 induced by substance P
- (2014) Florin Tuluc et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Tachykinins and Their Receptors: Contributions to Physiological Control and the Mechanisms of Disease
- (2014) Martin S. Steinhoff et al. PHYSIOLOGICAL REVIEWS
- Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages
- (2014) Meera Rath et al. Frontiers in Immunology
- From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation
- (2014) Paola Italiani et al. Frontiers in Immunology
- AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration
- (2013) Rémi Mounier et al. Cell Metabolism
- Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus
- (2013) Ravid Shechter et al. IMMUNITY
- Rapamycin unbalances the polarization of human macrophages to M1
- (2013) Alessia Mercalli et al. IMMUNOLOGY
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- Substance P reduces apoptotic cell death possibly by modulating the immune response at the early stage after spinal cord injury
- (2013) Mei Hua Jiang et al. NEUROREPORT
- SMAD-PI3K-Akt-mTOR Pathway Mediates BMP-7 Polarization of Monocytes into M2 Macrophages
- (2013) Crystal Rocher et al. PLoS One
- Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions
- (2013) G. Fejer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The TSC-mTOR pathway regulates macrophage polarization
- (2013) Vanessa Byles et al. Nature Communications
- Lesional Accumulation of CD163+ Macrophages/microglia in Rat Traumatic Brain Injury
- (2012) Zhiren Zhang et al. BRAIN RESEARCH
- Polarizing Macrophages through Reprogramming of Glucose Metabolism
- (2012) Julianna Blagih et al. Cell Metabolism
- The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
- (2012) Arvand Haschemi et al. Cell Metabolism
- Orchestration of Metabolism by Macrophages
- (2012) Subhra K. Biswas et al. Cell Metabolism
- Macrophage plasticity and polarization: in vivo veritas
- (2012) Antonio Sica et al. JOURNAL OF CLINICAL INVESTIGATION
- Defining GM-CSF- and Macrophage-CSF-Dependent Macrophage Responses by In Vitro Models
- (2012) D. C. Lacey et al. JOURNAL OF IMMUNOLOGY
- Substance P induces M2-type macrophages after spinal cord injury
- (2012) Mei H. Jiang et al. NEUROREPORT
- GM-CSF Priming Drives Bone Marrow-Derived Macrophages to a Pro-Inflammatory Pattern and Downmodulates PGE2 in Response to TLR2 Ligands
- (2012) Carlos Arterio Sorgi et al. PLoS One
- Inflammation: Cell Recruitment versus Local Proliferation
- (2011) Laura Helming CURRENT BIOLOGY
- Editorial: Switching on arginase in M2 macrophages
- (2011) Volker Briken et al. JOURNAL OF LEUKOCYTE BIOLOGY
- IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
- (2011) Thomas Krausgruber et al. NATURE IMMUNOLOGY
- Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation
- (2011) S. J. Jenkins et al. SCIENCE
- Control of Macrophage Activation and Function by PPARs
- (2010) Ajay Chawla CIRCULATION RESEARCH
- Alternative Activation of Macrophages: Mechanism and Functions
- (2010) Siamon Gordon et al. IMMUNITY
- Monocytes in atherosclerosis: subsets and functions
- (2010) Kevin J. Woollard et al. Nature Reviews Cardiology
- The role of endothelial function and its assessment in rheumatoid arthritis
- (2010) Faisel Khan et al. Nature Reviews Rheumatology
- A new role of substance P as an injury-inducible messenger for mobilization of CD29+ stromal-like cells
- (2009) Hyun Sook Hong et al. NATURE MEDICINE
- Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice
- (2009) Ravid Shechter et al. PLOS MEDICINE
- Substance P enhances NF-κB transactivation and chemokine response in murine macrophages via ERK1/2 and p38 MAPK signaling pathways
- (2008) Jia Sun et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Substance P (SP) enhances CCL5-induced chemotaxis and intracellular signaling in human monocytes, which express the truncated neurokinin-1 receptor (NK1R)
- (2008) I. Chernova et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The immune system and cardiac repair
- (2008) N FRANGOGIANNIS PHARMACOLOGICAL RESEARCH
- Macrophage Phenotype as a Determinant of Biologic Scaffold Remodeling
- (2008) Stephen F. Badylak et al. TISSUE ENGINEERING PART A
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started